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Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Quantitative Methods · Quantitative Biology 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

Histopathological analysis has been transformed by serial section-based methods, advancing beyond traditional 2D histology to enable volumetric and microstructural insights in oncology and inflammatory disease diagnostics. This review…

Tissues and Organs · Quantitative Biology 2025-08-05 Zhenfeng Zhuang , Min Cen , Lei Jiang , Qiong Peng , Yihuang Hu , Hong-Yu Zhou , Liansheng Wang

Radiological imaging of prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired at different times, with patient movement between scans, or with different…

Computer Vision and Pattern Recognition · Computer Science 2013-11-05 Xin Zhao , Arie Kaufman

Neural image compression (NIC) has received considerable attention due to its significant advantages in feature representation and data optimization. However, most existing NIC methods for volumetric medical images focus solely on improving…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Jietao Chen , Weijie Chen , Qianjian Xing , Feng Yu

Accurate volume estimation of objects from visual data is a long-standing challenge in computer vision with significant applications in robotics, logistics, and smart health. Existing methods often rely on complex 3D reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Gautham Vinod , Bruce Coburn , Siddeshwar Raghavan , Fengqing Zhu

Recently, 3D Gaussian Splatting (3DGS) has enabled photorealistic view synthesis at high inference speeds. However, its splatting-based rendering model makes several approximations to the rendering equation, reducing physical accuracy. We…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Chinmay Talegaonkar , Yash Belhe , Ravi Ramamoorthi , Nicholas Antipa

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

Shape reconstruction from imaging volumes is a recurring need in medical image analysis. Common workflows start with a segmentation step, followed by careful post-processing and,finally, ad hoc meshing algorithms. As this sequence can be…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Antonio Pepe , Richard Schussnig , Jianning Li , Christina Gsaxner , Dieter Schmalstieg , Jan Egger

Breast MRI provides high-resolution volumetric imaging critical for tumor assessment and treatment planning, yet manual interpretation of 3D scans remains labor-intensive and subjective. While AI-powered tools hold promise for accelerating…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Solha Kang , Eugene Kim , Joris Vankerschaver , Utku Ozbulak

Intensity variations in image texture can provide powerful quantitative information about physical properties of biological tissue. However, tissue patterns can vary according to the utilized imaging system and are intrinsically correlated…

Computer Vision and Pattern Recognition · Computer Science 2016-01-15 O. S. Al-Kadi , Daniel Y. F. Chung , Robert C. Carlisle , Constantin C. Coussios , J. Alison Noble

We present a novel 3D mapping method leveraging the recent progress in neural implicit representation for 3D reconstruction. Most existing state-of-the-art neural implicit representation methods are limited to object-level reconstructions…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Stefan Lionar , Lukas Schmid , Cesar Cadena , Roland Siegwart , Andrei Cramariuc

Diffusion magnetic resonance imaging (dMRI) is an important tool in characterizing tissue microstructure based on biophysical models, which are complex and highly non-linear. Resolving microstructures with optimization techniques is prone…

Signal Processing · Electrical Eng. & Systems 2022-05-16 Tianshu Zheng , Cong Sun , Weihao Zheng , Wen Shi , Haotian Li , Yi Sun , Yi Zhang , Guangbin Wang , Chuyang Ye , Dan Wu

Delineating 3D blood vessels is essential for clinical diagnosis and treatment, however, is challenging due to complex structure variations and varied imaging conditions. Supervised deep learning has demonstrated its superior capacity in…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Huai Chen , Xiuying Wang , Lisheng Wang

Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…

We introduce DMTet, a deep 3D conditional generative model that can synthesize high-resolution 3D shapes using simple user guides such as coarse voxels. It marries the merits of implicit and explicit 3D representations by leveraging a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Tianchang Shen , Jun Gao , Kangxue Yin , Ming-Yu Liu , Sanja Fidler

Generalizable neural surface reconstruction has become a compelling technique to reconstruct from few images without per-scene optimization, where dense 3D feature volume has proven effective as a global representation of scenes. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Aoxiang Fan , Corentin Dumery , Nicolas Talabot , Hieu Le , Pascal Fua

This work introduces Structured 3D-SVD as a practical framework for the reconstruction, compression, and analysis of biological volumetric data. Inspired by the logic of matrix singular value decomposition (SVD), the proposed approach…

Image and Video Processing · Electrical Eng. & Systems 2026-04-21 Mario Aragonés Lozano , Oscar Romero , Antonio León

Deep generative models can synthesize photorealistic images of human faces with novel identities. However, a key challenge to the wide applicability of such techniques is to provide independent control over semantically meaningful…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Marcel C. Bühler , Abhimitra Meka , Gengyan Li , Thabo Beeler , Otmar Hilliges

Two-dimensional (2D) freehand ultrasonography is one of the most commonly used medical imaging modalities, particularly in obstetrics and gynaecology. However, it only captures 2D cross-sectional views of inherently 3D anatomies, losing…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Mark C. Eid , Pak-Hei Yeung , Madeleine K. Wyburd , João F. Henriques , Ana I. L. Namburete

Annotating 3D medical images demands expert knowledge and is time-consuming. As a result, semi-supervised learning (SSL) approaches have gained significant interest in 3D medical image segmentation. The significant size differences among…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Yuliang Gu , Yepeng Liu , Zhichao Sun , Jinchi Zhu , Yongchao Xu , Laurent Najman