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Related papers: AI-driven 3D Spatial Transcriptomics

200 papers

Fully convolutional networks have become the backbone of modern medical imaging due to their ability to learn multi-scale representations and perform end-to-end inference. Yet their potential for slice-to-volume reconstruction (SVR), the…

Image and Video Processing · Electrical Eng. & Systems 2026-01-13 Margherita Firenze , Sean I. Young , Clinton J. Wang , Hyuk Jin Yun , Elfar Adalsteinsson , Kiho Im , P. Ellen Grant , Polina Golland

Characterization of breast parenchyma on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Current quantitative approaches, including radiomics and…

Quantitative Methods · Quantitative Biology 2021-05-14 Fan Wang , Saarthak Kapse , Steven Liu , Prateek Prasanna , Chao Chen

We present a novel method for reconstructing clothed humans from a sparse set of, e.g., 1 to 6 RGB images. Despite impressive results from recent works employing deep implicit representation, we revisit the volumetric approach and…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Sicong Tang , Guangyuan Wang , Qing Ran , Lingzhi Li , Li Shen , Ping Tan

Spatial control methods using additional modules on pretrained diffusion models have gained attention for enabling conditional generation in natural images. These methods guide the generation process with new conditions while leveraging the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Suhyun Ahn , Wonjung Park , Jihoon Cho , Seunghyuck Park , Jinah Park

Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…

Recent advances in 3D imaging technologies provide novel insights to researchers and reveal finer and more detail of examined specimen, especially in the biomedical domain, but also impose huge challenges regarding scalability for automated…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Dominik Drees , Aaron Scherzinger , René Hägerling , Friedemann Kiefer , Xiaoyi Jiang

Cross-modal 3D medical image analysis requires voxelwise representations that remain anatomically consistent across imaging contrasts, scanners, and acquisition protocols. Recent work has shown that frozen 2D Vision Transformer (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guney Tombak , Ertunc Erdil , Ender Konukoglu

We explore a solution for learning disease signatures from weakly, yet easily obtainable, annotated volumetric medical imaging data by analyzing 3D volumes as a sequence of 2D images. We demonstrate the performance of our solution in the…

Computer Vision and Pattern Recognition · Computer Science 2020-01-27 Nathaniel Braman , David Beymer , Ehsan Dehghan

This paper presents Volumetric Transformer Pose estimator (VTP), the first 3D volumetric transformer framework for multi-view multi-person 3D human pose estimation. VTP aggregates features from 2D keypoints in all camera views and directly…

Computer Vision and Pattern Recognition · Computer Science 2023-08-07 Yuxing Chen , Renshu Gu , Ouhan Huang , Gangyong Jia

Spatial transcriptomics (ST) profiles gene expression across a tissue section while preserving the spatial coordinates. Because current ST technologies typically profile two-dimensional tissue slices, integrating and aligning slices from…

Quantitative Methods · Quantitative Biology 2026-03-20 Yaqi Wu , Jingfeng Wang , Xin Maizie Zhou , Yanxiang Zhao , Zixuan Cang

Target volume contouring for radiation therapy is considered significantly more challenging than the normal organ segmentation tasks as it necessitates the utilization of both image and text-based clinical information. Inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Yeona Cho , Ik Jae Lee , Jin Sung Kim , Jong Chul Ye

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

Spatial graphs provide a lightweight and elegant representation of curvilinear anatomical structures such as blood vessels, lung airways, and neuronal networks. Accurately modeling these graphs is crucial in clinical and (bio-)medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Chinmay Prabhakar , Bastian Wittmann , Tamaz Amiranashvili , Paul Büschl , Ezequiel de la Rosa , Julian McGinnis , Benedikt Wiestler , Bjoern Menze , Suprosanna Shit

Despite the impressive progress of telepresence systems for room-scale scenes with static and dynamic scene entities, expanding their capabilities to scenarios with larger dynamic environments beyond a fixed size of a few square-meters…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Leif Van Holland , Patrick Stotko , Stefan Krumpen , Reinhard Klein , Michael Weinmann

Cross-modality medical image synthesis is a critical topic and has the potential to facilitate numerous applications in the medical imaging field. Despite recent successes in deep-learning-based generative models, most current medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Lingting Zhu , Zeyue Xue , Zhenchao Jin , Xian Liu , Jingzhen He , Ziwei Liu , Lequan Yu

Histological images are critical in the diagnosis and treatment of cancers. Unfortunately, the current method for capturing these microscopy images require resource intensive tissue preparation that delays diagnosis for many days to a few…

Recently deep residual learning with residual units for training very deep neural networks advanced the state-of-the-art performance on 2D image recognition tasks, e.g., object detection and segmentation. However, how to fully leverage…

Computer Vision and Pattern Recognition · Computer Science 2016-08-23 Hao Chen , Qi Dou , Lequan Yu , Pheng-Ann Heng

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

We present ShaDDR, an example-based deep generative neural network which produces a high-resolution textured 3D shape through geometry detailization and conditional texture generation applied to an input coarse voxel shape. Trained on a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-23 Qimin Chen , Zhiqin Chen , Hang Zhou , Hao Zhang

Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Inye Na , Nejung Rue , Jiwon Chung , Hyunjin Park