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Resection and whole brain radiotherapy (WBRT) are the standards of care for the treatment of patients with brain metastases (BM) but are often associated with cognitive side effects. Stereotactic radiosurgery (SRS) involves a more targeted…

Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Denis Prokopenko , Joël Valentin Stadelmann , Heinrich Schulz , Steffen Renisch , Dmitry V. Dylov

Computed tomography (CT) is a widely used imaging modality for medical diagnosis and treatment. In electroencephalography (EEG), CT imaging is necessary for co-registering with magnetic resonance imaging (MRI) and for creating more accurate…

Medical Physics · Physics 2019-06-12 Andreas D. Lauritzen , Xenophon Papademetris , Sergei Turovets , John A. Onofrey

Diversity in data is critical for the successful training of deep learning models. Leveraged by a recurrent generative adversarial network, we propose the CT-SGAN model that generates large-scale 3D synthetic CT-scan volumes ($\geq…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Ahmad Pesaranghader , Yiping Wang , Mohammad Havaei

Early detection of breast cancer is critical for improving patient outcomes. While mammography remains the primary screening modality, magnetic resonance imaging (MRI) is increasingly recommended as a supplemental tool for women with dense…

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 John R. McNulty , Lee Kho , Alexandria L. Case , Charlie Fornaca , Drew Johnston , David Slater , Joshua M. Abzug , Sybil A. Russell

Deep learning techniques, particularly convolutional neural networks (CNNs), have gained traction for synthetic computed tomography (sCT) generation from Magnetic resonance imaging (MRI), Cone-beam computed tomography (CBCT) and PET. In…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Satoshi Kondo , Satoshi Kasai , Kousuke Hirasawa

In the field of radiotherapy, accurate imaging and image registration are of utmost importance for precise treatment planning. Magnetic Resonance Imaging (MRI) offers detailed imaging without being invasive and excels in soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Saba Nikbakhsh , Lachin Naghashyar , Morteza Valizadeh , Mehdi Chehel Amirani

Achieving robust performance and fairness across diverse patient populations remains a challenge in developing clinically deployable deep learning models for diagnostic imaging. Synthetic data generation has emerged as a promising strategy…

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

This paper proposes a novel, unsupervised super-resolution (SR) approach for performing the SR of a clinical CT into the resolution level of a micro CT ($\mu$CT). The precise non-invasive diagnosis of lung cancer typically utilizes clinical…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Tong Zheng , Hirohisa Oda , Masahiro Oda , Shota Nakamura , Masaki Mori , Hirotsugu Takabatake , Hiroshi Natori , Kensaku Mori

Motivated by the lack of publicly available datasets of chest radiographs of positive patients with Coronavirus disease 2019 (COVID-19), we build the first-of-its-kind open dataset of synthetic COVID-19 chest X-ray images of high fidelity…

Image and Video Processing · Electrical Eng. & Systems 2020-10-21 Hasib Zunair , A. Ben Hamza

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are highly sensitive to changes in resolution and contrast: even…

Image and Video Processing · Electrical Eng. & Systems 2023-03-01 Benjamin Billot , Douglas N. Greve , Oula Puonti , Axel Thielscher , Koen Van Leemput , Bruce Fischl , Adrian V. Dalca , Juan Eugenio Iglesias

Pancreatic cancer remains one of the leading causes of cancer-related mortality worldwide. Precise segmentation of pancreatic tumors from medical images is a bottleneck for effective clinical decision-making. However, achieving a high…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Linkai Peng , Zheyuan Zhang , Gorkem Durak , Frank H. Miller , Alpay Medetalibeyoglu , Michael B. Wallace , Ulas Bagci

Recently, a new form of magnetic resonance imaging (MRI) called synthetic correlated diffusion (CDI$^s$) imaging was introduced and showed considerable promise for clinical decision support for cancers such as prostate cancer when compared…

Image and Video Processing · Electrical Eng. & Systems 2023-04-13 Chi-en Amy Tai , Hayden Gunraj , Alexander Wong

There is no consensus in the field of synthetic data on concise metrics for quality evaluations or benchmarks on large health datasets, such as historical epidemiological data. This study presents an evaluation of seven recent models from…

Machine Learning · Computer Science 2026-04-20 Jean-Baptiste Escudié , Benjamin Barnes , Stefan Meisegeier , Klaus Kraywinkel , Fabian Prasser , Nils Körber

Medical imaging analysis faces challenges such as data scarcity, high annotation costs, and privacy concerns. This paper introduces the Medical AI for Synthetic Imaging (MAISI), an innovative approach using the diffusion model to generate…

Image and Video Processing · Electrical Eng. & Systems 2025-12-16 Pengfei Guo , Can Zhao , Dong Yang , Ziyue Xu , Vishwesh Nath , Yucheng Tang , Benjamin Simon , Mason Belue , Stephanie Harmon , Baris Turkbey , Daguang Xu

Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…