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Mixed-integer programming (MIP) is a well-established framework for computer-aided molecular design (CAMD). By precisely encoding the molecular space and score functions, e.g., a graph neural network, the molecular design problem is…

Computational Engineering, Finance, and Science · Computer Science 2024-11-26 Shiqiang Zhang , Christian W. Feldmann , Frederik Sandfort , Miriam Mathea , Juan S. Campos , Ruth Misener

In this paper, we describe a comprehensive algorithmic framework for solving mixed integer bilevel linear optimization problems (MIBLPs) using a generalized branch-and-cut approach. The framework presented merges features from existing…

Optimization and Control · Mathematics 2021-04-20 Sahar Tahernejad , Ted K. Ralphs , Scott T. DeNegre

We consider the problem of minimizing the makespan on batch processing identical machines, subject to compatibility constraints, where two jobs are compatible if they can be processed simultaneously in a same batch. These constraints are…

Discrete Mathematics · Computer Science 2023-09-07 Khaoula Bouakaz , Mourad Boudhar

Governments across the world are planning to increase the share of renewables in their energy systems. The siting of new wind and solar power plants requires close coordination with grid planning, and hence co-optimization of investment in…

Optimization and Control · Mathematics 2020-09-25 Fabian Neumann , Tom Brown

Assembly line balancing problems consist in partitioning the work necessary to assemble a number of products among different stations of an assembly line. We present a hybrid approach for solving such problems, which combines constraint…

Discrete Mathematics · Computer Science 2007-05-23 Alexander Bockmayr , Nicolai Pisaruk

Mixed-Integer Programming (MIP), particularly Mixed-Integer Linear Programming (MILP) and Mixed-Integer Quadratic Programming (MIQP), has found extensive applications in domains such as portfolio optimization and network flow control, which…

Optimization and Control · Mathematics 2026-02-03 Zayn Wang

Besides training, mathematical optimization is also used in deep learning to model and solve formulations over trained neural networks for purposes such as verification, compression, and optimization with learned constraints. However,…

Optimization and Control · Mathematics 2024-01-30 Jiatai Tong , Junyang Cai , Thiago Serra

Employee rostering is a process of assigning available employees to open shifts. Automating it has ubiquitous practical benefits for nearly all industries, such as reducing manual workload and producing flexible, high-quality schedules. In…

Artificial Intelligence · Computer Science 2021-11-23 Jangwon Park , Evangelos Vrettos

This paper analyzes the integration of artificial intelligence (AI) with mixed integer linear programming (MILP) to address complex optimization challenges in air transportation with explainability. The study aims to validate the use of…

In this paper, we consider the network slicing problem which attempts to map multiple customized virtual network requests (also called services) to a common shared network infrastructure and allocate network resources to meet diverse…

Information Theory · Computer Science 2022-03-01 Wei-Kun Chen , Ya-Feng Liu , Yu-Hong Dai , Zhi-Quan Luo

Data-driven inverse optimization for mixed-integer linear programs (MILPs), which seeks to learn an objective function and constraints consistent with observed decisions, is important for building accurate mathematical models in a variety…

Optimization and Control · Mathematics 2026-02-17 Akira Kitaoka

Mixed-integer rounding (MIR) cutting planes (cuts) are effective at improving the strength of a linear relaxation for mixed-integer linear programming (MIP) problems. The cuts in this family are derived by aggregating constraints then…

Optimization and Control · Mathematics 2024-12-16 Oscar Guaje , Arnaud Deza , Aleksandr M. Kazachkov , Elias B. Khalil

Integer linear programs (ILPs) are commonly employed to model diverse practical problems such as scheduling and planning. Recently, machine learning techniques have been utilized to solve ILPs. A straightforward idea is to train a model via…

Optimization and Control · Mathematics 2025-01-08 Qian Chen , Tianjian Zhang , Linxin Yang , Qingyu Han , Akang Wang , Ruoyu Sun , Xiaodong Luo , Tsung-Hui Chang

This paper considers how to fuse Machine Learning (ML) and optimization to solve large-scale Supply Chain Planning (SCP) optimization problems. These problems can be formulated as MIP models which feature both integer (non-binary) and…

Machine Learning · Computer Science 2025-04-11 Vahid Eghbal Akhlaghi , Reza Zandehshahvar , Pascal Van Hentenryck

Efficient planning of activities is essential for modern industrial assembly lines to uphold manufacturing standards, prevent project constraint violations, and achieve cost-effective operations. While exact solutions to such challenges can…

Artificial Intelligence · Computer Science 2025-07-23 Ali Mohamed Ali , Luca Tirel , Hashim A. Hashim

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

Mixed Integer Programming (MIP) is one of the most widely used modeling techniques for combinatorial optimization problems. In many applications, a similar MIP model is solved on a regular basis, maintaining remarkable similarities in model…

Artificial Intelligence · Computer Science 2019-09-10 Jian-Ya Ding , Chao Zhang , Lei Shen , Shengyin Li , Bing Wang , Yinghui Xu , Le Song

Current state-of-the-art solvers for mixed-integer programming (MIP) problems are designed to perform well on a wide range of problems. However, for many real-world use cases, problem instances come from a narrow distribution. This has…

Optimization and Control · Mathematics 2022-02-15 Charly Robinson La Rocca , Emma Frejinger , Jean-François Cordeau

This work focuses on support vector machine (SVM) with feature selection. A MILP formulation is proposed for the problem. The choice of suitable features to construct the separating hyperplanes has been modelled in this formulation by…

Optimization and Control · Mathematics 2018-08-08 Martine Labbé , Luisa I. Martínez-Merino , Antonio M. Rodríguez-Chía

Efficient management of aircraft MRO hangars requires the integration of spatial layout with time-continuous scheduling to minimize operational costs. We propose a continuous-time mixed-integer linear program that jointly optimizes aircraft…

Optimization and Control · Mathematics 2025-09-09 Shayan Farhang Pazhooh , Hossein Shams Shemirani