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The use of Large Language Models (LLMs) has drawn growing interest within the scientific community. LLMs can handle large volumes of textual data and support methods for evidence synthesis. Although recent studies highlight the potential of…

Software Engineering · Computer Science 2026-02-12 Cauã Ferreira Barros , Marcos Kalinowski , Mohamad Kassab , Valdemar Vicente Graciano Neto

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

Computation and Language · Computer Science 2025-11-25 Yanjun Lyu , Zihao Wu , Lu Zhang , Jing Zhang , Yiwei Li , Wei Ruan , Zhengliang Liu , Zeyu Zhang , Xiang Li , Rongjie Liu , Chao Huang , Wentao Li , Tianming Liu , Dajiang Zhu

The advancement of Large Language Models (LLMs), including GPT-4, provides exciting new opportunities for generative design. We investigate the application of this tool across the entire design and manufacturing workflow. Specifically, we…

The rapid advances in Large Language Models (LLMs) have the potential to transform manufacturing industry, offering new opportunities to optimize processes, improve efficiency, and drive innovation. This paper provides a comprehensive…

Large Language Model (LLM) has transformative potential in various domains, including recommender systems (RS). There have been a handful of research that focuses on empowering the RS by LLM. However, previous efforts mainly focus on LLM as…

Information Retrieval · Computer Science 2025-03-11 Qidong Liu , Xiangyu Zhao , Yuhao Wang , Yejing Wang , Zijian Zhang , Yuqi Sun , Xiang Li , Maolin Wang , Pengyue Jia , Chong Chen , Wei Huang , Feng Tian

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Building effective machine learning (ML) workflows to address complex tasks is a primary focus of the Automatic ML (AutoML) community and a critical step toward achieving artificial general intelligence (AGI). Recently, the integration of…

Machine Learning · Computer Science 2024-12-30 Yang Gu , Hengyu You , Jian Cao , Muran Yu , Haoran Fan , Shiyou Qian

Large language models (LLMs) represent a new paradigm for processing unstructured data, with applications across an unprecedented range of domains. In this paper, we address, through two arguments, whether the development and application of…

Methodology · Statistics 2026-02-03 Weijie Su

Recently, tool learning with large language models (LLMs) has emerged as a promising paradigm for augmenting the capabilities of LLMs to tackle highly complex problems. Despite growing attention and rapid advancements in this field, the…

Computation and Language · Computer Science 2024-11-05 Changle Qu , Sunhao Dai , Xiaochi Wei , Hengyi Cai , Shuaiqiang Wang , Dawei Yin , Jun Xu , Ji-Rong Wen

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large language models (LLMs) have revolutionized natural language processing with their exceptional understanding, synthesizing, and reasoning capabilities. However, deploying LLMs on resource-constrained edge devices presents significant…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-25 Yue Zheng , Yuhao Chen , Bin Qian , Xiufang Shi , Yuanchao Shu , Jiming Chen

Large language models (LLMs) are increasingly being deployed across disciplines due to their advanced reasoning and problem solving capabilities. To measure their effectiveness, various benchmarks have been developed that measure aspects of…

Proteins are fundamental components of biological systems and can be represented through various modalities, including sequences, structures, and textual descriptions. Despite the advances in deep learning and scientific large language…

Machine Learning · Computer Science 2024-07-15 Zhiyuan Chen , Tianhao Chen , Chenggang Xie , Yang Xue , Xiaonan Zhang , Jingbo Zhou , Xiaomin Fang

The rapid advancement of Large Language Models (LLMs) has opened new possibilities in Multi-Robot Systems (MRS), enabling enhanced communication, task allocation and planning, and human-robot interaction. Unlike traditional single-robot and…

Robotics · Computer Science 2026-05-05 Peihan Li , Zijian An , Shams Abrar , Lifeng Zhou

The classification of genetic variants, particularly Variants of Uncertain Significance (VUS), poses a significant challenge in clinical genetics and precision medicine. Large Language Models (LLMs) have emerged as transformative tools in…

Given the increasing demands in computer programming education and the rapid advancement of large language models (LLMs), LLMs play a critical role in programming education. This study provides a systematic review of selected empirical…

Computers and Society · Computer Science 2025-06-30 Meina Zhu , Lanyu Xu , Barbara Ericson

The rapid advancement of artificial intelligence, particularly with the development of Large Language Models (LLMs) built on the transformer architecture, has redefined the capabilities of natural language processing. These models now…

Computation and Language · Computer Science 2025-02-11 Andrea Matarazzo , Riccardo Torlone

Large Language Models (LLMs) have recently emerged as powerful tools in cybersecurity, offering advanced capabilities in malware detection, generation, and real-time monitoring. Numerous studies have explored their application in…

Cryptography and Security · Computer Science 2025-04-11 Hamed Jelodar , Samita Bai , Parisa Hamedi , Hesamodin Mohammadian , Roozbeh Razavi-Far , Ali Ghorbani

Large Language Models (LLMs) have revolutionized the field of Natural Language Processing (NLP) by automating traditional labor-intensive tasks and consequently accelerated the development of computer-aided applications. As researchers…

Computation and Language · Computer Science 2025-06-24 Summra Saleem , Muhammad Nabeel Asim , Shaista Zulfiqar , Andreas Dengel
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