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Multi-sequence MRIs can be necessary for reliable diagnosis in clinical practice due to the complimentary information within sequences. However, redundant information exists across sequences, which interferes with mining efficient…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Luyi Han , Tao Tan , Tianyu Zhang , Yunzhi Huang , Xin Wang , Yuan Gao , Jonas Teuwen , Ritse Mann

In the rapidly evolving landscape of artificial intelligence, generative models such as Generative Adversarial Networks (GANs) and Diffusion Models have become cornerstone technologies, driving innovation in diverse fields from art creation…

Machine Learning · Computer Science 2024-08-01 Jack He , Jianxing Zhao , Andrew Bai , Cho-Jui Hsieh

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

Machine Learning · Computer Science 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

Ensuring the generalisability of clinical machine learning (ML) models across diverse healthcare settings remains a significant challenge due to variability in patient demographics, disease prevalence, and institutional practices. Existing…

Machine Learning · Computer Science 2025-04-30 Bradley Segal , Joshua Fieggen , David Clifton , Lei Clifton

Generative artificial intelligence holds significant potential for abuse, and generative image detection has become a key focus of research. However, existing methods primarily focused on detecting a specific generative model and…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Peipei Yuan , Zijing Xie , Shuo Ye , Hong Chen , Yulong Wang

Deep learning in medical imaging is often limited by scarce and imbalanced annotated data. We present SSGNet, a unified framework that combines class specific generative modeling with iterative semisupervised pseudo labeling to enhance both…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Mosong Ma , Tania Stathaki , Michalis Lazarou

Deep generative models are often trained on sensitive data, such as genetic sequences, health data, or more broadly, any copyrighted, licensed or protected content. This raises critical concerns around privacy-preserving synthetic data, and…

In medical imaging, access to data is commonly limited due to patient privacy restrictions and the issue that it can be difficult to acquire enough data in the case of rare diseases.[1] The purpose of this investigation was to develop a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 John R. McNulty , Lee Kho , Alexandria L. Case , Charlie Fornaca , Drew Johnston , David Slater , Joshua M. Abzug , Sybil A. Russell

Paucity of medical data severely limits the generalizability of diagnostic ML models, as the full spectrum of disease variability can not be represented by a small clinical dataset. To address this, diffusion models (DMs) have been…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Janet Wang , Yunbei Zhang , Zhengming Ding , Jihun Hamm

We performed a billion locality sensitive hash comparisons between artificially generated data samples to answer the critical question - can we reproduce the results of generative AI models? Reproducibility is one of the pillars of…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-02-07 Edward Kim , Isamu Isozaki , Naomi Sirkin , Michael Robson

The rapid advancement of generative models has introduced serious risks, including deepfake techniques for facial synthesis and editing. Traditional approaches rely on training classifiers and enhancing generalizability through various…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Chung-Ting Tsai , Ching-Yun Ko , I-Hsin Chung , Yu-Chiang Frank Wang , Pin-Yu Chen

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

The rapid development of generative models has made it increasingly crucial to develop detectors that can reliably detect synthetic images. Although most of the work has now focused on cross-generator generalization, we argue that this…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Amirtaha Amanzadi , Zahra Dehghanian , Hamid Beigy , Hamid R. Rabiee

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

Recent advances in image generation have led to the widespread availability of highly realistic synthetic media, increasing the difficulty of reliable deepfake detection. A key challenge is generalization, as detectors trained on a narrow…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Yichen Jiang , Mohammed Talha Alam , Sohail Ahmed Khan , Duc-Tien Dang-Nguyen , Fakhri Karray

Generative latent diffusion models have been established as state-of-the-art in data generation. One promising application is generation of realistic synthetic medical imaging data for open data sharing without compromising patient privacy.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Salman Ul Hassan Dar , Arman Ghanaat , Jannik Kahmann , Isabelle Ayx , Theano Papavassiliu , Stefan O. Schoenberg , Sandy Engelhardt

Recent advances in generative image modeling have achieved visual realism sufficient to deceive human experts, yet their potential for privacy preserving data sharing remains insufficiently understood. A central obstacle is the absence of…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Scientific image manipulation in biomedical publications poses a growing threat to research integrity and reproducibility. Unlike natural image forensics, biomedical forgery detection is uniquely challenging due to domain-specific…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Soumyaroop Nandi , Prem Natarajan

Low-field to high-field MRI synthesis has emerged as a cost-effective strategy to enhance image quality under hardware and acquisition constraints, particularly in scenarios where access to high-field scanners is limited or impractical.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Zhenxuan Zhang , Peiyuan Jing , Ruicheng Yuan , Liwei Hu , Anbang Wang , Fanwen Wang , Yinzhe Wu , Kh Tohidul Islam , Zhaolin Chen , Zi Wang , Peter Lally , Guang Yang