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The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh

We present a general framework for applying linear quantum error mitigation (QEM) techniques directly to physical qubits within a logical qubit to suppress logical errors. By exploiting the linearity of quantum error correction (QEC), we…

Quantum Physics · Physics 2026-01-27 Minjun Jeon , Zhenyu Cai

Efficiently embedding high-dimensional datasets onto noisy and low-qubit quantum systems is a significant barrier to practical Quantum Machine Learning (QML). Approaches such as quantum autoencoders can be constrained by current hardware…

Quantum Physics · Physics 2025-06-25 Hevish Cowlessur , Tansu Alpcan , Chandra Thapa , Seyit Camtepe , Neel Kanth Kundu

The use of quantum computing for machine learning is among the most promising applications of quantum technologies. Quantum models inspired by classical algorithms are developed to explore some possible advantages over classical approaches.…

Recent advancements in quantum algorithms have reached a state where we can consider how to capitalize on quantum and classical computational resources to accelerate molecular resonance state identification. Here we identify molecular…

Quantum Physics · Physics 2026-03-26 Jingcheng Dai , Atharva Vidwans , Eric H. Wan , Alexander X. Miller , Micheline B. Soley

The lack of evidence for new interactions and particles at the Large Hadron Collider has motivated the high-energy physics community to explore model-agnostic data-analysis approaches to search for new physics. Autoencoders are unsupervised…

High Energy Physics - Phenomenology · Physics 2022-05-20 Vishal S. Ngairangbam , Michael Spannowsky , Michihisa Takeuchi

The increasing scale of deep learning models in high-energy physics (HEP) has posed challenges to their deployment on low-power, latency-sensitive platforms, such as FPGAs and ASICs used in trigger systems, as well as in offline data…

High Energy Physics - Phenomenology · Physics 2025-08-12 Saurabh Rai , Prisha , Jitendra Kumar

Quantum homomorphic encryption (QHE), allows a quantum cloud server to compute on private data as uploaded by a client. We provide a proof-of-concept software simulation for QHE, according to the "EPR" scheme of Broadbent and Jeffery, for…

Quantum Physics · Physics 2025-07-29 Sohrab Ganjian , Connor Paddock , Anne Broadbent

This work presents novel discrete event-based simulation algorithms based on the Quantized State System (QSS) numerical methods. QSS provides attractive features for particle transportation processes, in particular a very efficient handling…

Computational Physics · Physics 2021-09-16 Lucio Santi , Lucas Rossi , Rodrigo Castro

Quantum phase estimation (QPE) serves as a building block of many different quantum algorithms and finds important applications in computational chemistry problems. Despite the rapid development of quantum hardware, experimental…

Quantum Physics · Physics 2024-03-01 Kentaro Yamamoto , Samuel Duffield , Yuta Kikuchi , David Muñoz Ramo

Classical deep neural networks can learn rich multi-particle correlations in collider data, but their inductive biases are rarely anchored in physics structure. We propose quantum-informed neural networks (QINNs), a general framework that…

High Energy Physics - Phenomenology · Physics 2025-10-22 Aritra Bal , Markus Klute , Benedikt Maier , Melik Oughton , Eric Pezone , Michael Spannowsky

We propose a quantum-classical hybrid algorithm to encode a given arbitrarily quantum state $\vert \Psi \rangle$ onto an optimal quantum circuit $\hat{\mathcal{C}}$ with a finite number of single- and two-qubit quantum gates. The proposed…

Quantum Physics · Physics 2024-10-16 Tomonori Shirakawa , Hiroshi Ueda , Seiji Yunoki

Some of the biggest achievements of the modern era of particle physics, such as the discovery of the Higgs boson, have been made possible by the tremendous effort in building and operating large-scale experiments like the Large Hadron…

A longstanding computational challenge is the accurate simulation of many-body particle systems. Especially for deriving key characteristics of high-impact but complex systems such as battery materials and high entropy alloys (HEA). While…

Quantum Physics · Physics 2025-11-20 Koen Mesman , Yinglu Tang , Matthias Moller , Boyang Chen , Sebastian Feld

Autoencoders are fundamental tools in classical computing for unsupervised feature extraction, dimensionality reduction, and generative learning. The Quantum Autoencoder (QAE), introduced by Romero J.[2017 Quantum Sci. Technol. 2 045001],…

Quantum Physics · Physics 2025-02-12 Li-An Lo , Li-Yi Hsu , En-Jui Kuo

Recent progress in quantum algorithms and hardware indicates the potential importance of quantum computing in the near future. However, finding suitable application areas remains an active area of research. Quantum machine learning is…

Machine Learning · Computer Science 2020-07-16 Nicholas Gao , Max Wilson , Thomas Vandal , Walter Vinci , Ramakrishna Nemani , Eleanor Rieffel

We present the first demonstration of an end-to-end pipeline with quantum error correction (QEC) for a quantum computation of the electronic structure of molecular systems. We calculate the ground-state energy of molecular hydrogen, using…

Quantum Machine Learning (QML) has emerged as a promising framework for exploring how quantum dynamics may enhance data processing tasks. Here we investigate Quantum Extreme Learning Machines (QELMs), a quantum analogue of classical Extreme…

Quantum Physics · Physics 2026-04-27 A. De Lorenzis , M. P. Casado , N. Lo Gullo , T. Lux , F. Plastina , A. Riera

Quantum Machine Learning investigates the possibility of quantum computers enhancing Machine Learning algorithms. Anomaly segmentation is a fundamental task in various domains to identify irregularities at sample level and can be addressed…

Quantum Physics · Physics 2025-01-31 Maria Francisca Madeira , Alessandro Poggiali , Jeanette Miriam Lorenz