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Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Hasan Iqbal , Umar Khalid , Jing Hua , Chen Chen

Anomaly detection aims to identify samples that deviate from the nominal data distribution and is central to many safety-critical applications. However, developing effective anomaly detection methods for categorical, mixed-type, and…

Machine Learning · Computer Science 2026-05-29 Lixing Zhang , Yuchen Liang , Liyan Xie

Unsupervised Anomalous Sound Detection (ASD) aims to design a generalizable method that can be used to detect anomalies when only normal sounds are given. In this paper, Anomalous Sound Detection based on Diffusion Models (ASD-Diffusion) is…

Sound · Computer Science 2024-09-25 Fengrun Zhang , Xiang Xie , Kai Guo

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

The high performance of denoising diffusion models for image generation has paved the way for their application in unsupervised medical anomaly detection. As diffusion-based methods require a lot of GPU memory and have long sampling times,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Julia Wolleb , Florentin Bieder , Paul Friedrich , Peter Zhang , Alicia Durrer , Philippe C. Cattin

Unsupervised anomaly detection (UAD) based on deep generative modelling has been increasingly explored for identifying pathological brain abnormalities without requiring voxel-level annotations. By learning the distribution of healthy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

Early detection of anomalies in medical images such as brain MRI is highly relevant for diagnosis and treatment of many conditions. Supervised machine learning methods are limited to a small number of pathologies where there is good…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Alexander Frotscher , Jaivardhan Kapoor , Thomas Wolfers , Christian F. Baumgartner

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

In medical applications, weakly supervised anomaly detection methods are of great interest, as only image-level annotations are required for training. Current anomaly detection methods mainly rely on generative adversarial networks or…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Julia Wolleb , Florentin Bieder , Robin Sandkühler , Philippe C. Cattin

Anomaly detection has garnered extensive applications in real industrial manufacturing due to its remarkable effectiveness and efficiency. However, previous generative-based models have been limited by suboptimal reconstruction quality,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Hui Zhang , Zheng Wang , Dan Zeng , Zuxuan Wu , Yu-Gang Jiang

Ultrasonography is an essential tool in mid-pregnancy for assessing fetal development, appreciated for its non-invasive and real-time imaging capabilities. Yet, the interpretation of ultrasound images is often complicated by acoustic…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Hanna Mykula , Lisa Gasser , Silvia Lobmaier , Julia A. Schnabel , Veronika Zimmer , Cosmin I. Bercea

Diffusion models have shown superior performance on unsupervised anomaly detection tasks. Since trained with normal data only, diffusion models tend to reconstruct normal counterparts of test images with certain noises added. However, these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Hang Yao , Ming Liu , Haolin Wang , Zhicun Yin , Zifei Yan , Xiaopeng Hong , Wangmeng Zuo

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

In this paper, we introduce Masked Anomaly Detection (MAD), a general self-supervised learning task for multivariate time series anomaly detection. With the increasing availability of sensor data from industrial systems, being able to…

Machine Learning · Computer Science 2022-10-04 Yiwei Fu , Feng Xue
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