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The Replica Exchange Wang-Landau Method is used to estimate the energy landscape of a polymer composed of a simple hydrophobic and polar sequence using the HP protein model. Calculations of state transitions between the energy levels of the…

Soft Condensed Matter · Physics 2023-03-22 Jared McDonald , Michael R. von Spakovsky , William T. Reynolds

Solving control tasks in complex environments automatically through learning offers great potential. While contemporary techniques from deep reinforcement learning (DRL) provide effective solutions, their decision-making is not transparent.…

Machine Learning · Computer Science 2023-07-03 Martin Tappler , Edi Muškardin , Bernhard K. Aichernig , Bettina Könighofer

Many systems in physics, engineering, and biology exhibit multiscale stochastic dynamics, where low-dimensional slow variables evolve under the influence of high-dimensional fast processes. In practice, observations are often limited to a…

Machine Learning · Statistics 2026-05-12 Anan Saha , Arnab Ganguly

We study the theoretical capacity to statistically learn local landscape information by Evolution Strategies (ESs). Specifically, we investigate the covariance matrix when constructed by ESs operating with the selection operator alone. We…

Neural and Evolutionary Computing · Computer Science 2016-06-24 Ofer M. Shir , Jonathan Roslund , Amir Yehudayoff

We present a method for generating, predicting, and using Spatiotemporal Occupancy Grid Maps (SOGM), which embed future semantic information of real dynamic scenes. We present an auto-labeling process that creates SOGMs from noisy real…

Robotics · Computer Science 2022-08-29 Hugues Thomas , Jian Zhang , Timothy D. Barfoot

Recent endeavors aimed at forecasting future traffic flow states through deep learning encounter various challenges and yield diverse outcomes. A notable obstacle arises from the substantial data requirements of deep learning models, a…

Machine Learning · Computer Science 2024-04-02 Zhaohui Yang , Kshitij Jerath

Ecological systems are emergent features of ecological and adaptive dynamics of a community of interacting species. By natural selection through the abiotic environment and by co-adaptation within the community, species evolve, thereby…

Populations and Evolution · Quantitative Biology 2018-07-03 Katharina Brinck , Henrik Jeldtoft Jensen

Almost all real-world networks are subject to constant evolution, and plenty of evolving networks have been investigated to uncover the underlying mechanisms for a deeper understanding of the organization and development of them. Compared…

Social and Information Networks · Computer Science 2016-10-12 Tao Wu , Leiting Chen

Translating the complex, multi-dimensional data from simulations of biomolecules to intuitive knowledge is a major challenge in computational chemistry and biology. The so-called "free energy landscape" is amongst the most fundamental…

Human-Computer Interaction · Computer Science 2018-03-16 Robert E. Arbon , Alex J. Jones , Lars A. Bratholm , Tom Mitchell , David R. Glowacki

In order to efficiently explore the chemical space of all possible small molecules, a common approach is to compress the dimension of the system to facilitate downstream machine learning tasks. Towards this end, we present a data driven…

Biomolecules · Quantitative Biology 2024-01-23 Paula Mercurio , Di Liu

Many sectors nowadays require accurate and coherent predictions across their organization to effectively operate. Otherwise, decision-makers would be planning using disparate views of the future, resulting in inconsistent decisions across…

Machine Learning · Computer Science 2023-02-09 Julien Leprince , Waqas Khan , Henrik Madsen , Jan Kloppenborg Møller , Wim Zeiler

Edge Computing enables low-latency processing for real-time applications but introduces challenges in power management due to the distributed nature of edge devices and their limited energy resources. This paper proposes a stochastic…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-07 Fabio Diniz Rossi

Recent years have seen a surge in interest in building deep learning-based fully data-driven models for weather prediction. Such deep learning models if trained on observations can mitigate certain biases in current state-of-the-art weather…

Machine Learning · Computer Science 2022-05-11 Ashesh Chattopadhyay , Jaideep Pathak , Ebrahim Nabizadeh , Wahid Bhimji , Pedram Hassanzadeh

In this paper we are concerned with the learnability of energies from data obtained by observing time evolutions of their critical points starting at random initial equilibria. As a byproduct of our theoretical framework we introduce the…

Machine Learning · Computer Science 2019-11-04 Stefano Almi , Massimo Fornasier , Richard Huber

In typical machine learning tasks and applications, it is necessary to obtain or create large labeled datasets in order to to achieve high performance. Unfortunately, large labeled datasets are not always available and can be expensive to…

Machine Learning · Statistics 2018-08-23 Rishi Sharma , Amir Barati Farimani , Joe Gomes , Peter Eastman , Vijay Pande

We introduce structured prediction energy networks (SPENs), a flexible framework for structured prediction. A deep architecture is used to define an energy function of candidate labels, and then predictions are produced by using…

Machine Learning · Computer Science 2016-09-08 David Belanger , Andrew McCallum

Structured Prediction Energy Networks (SPENs) are a simple, yet expressive family of structured prediction models (Belanger and McCallum, 2016). An energy function over candidate structured outputs is given by a deep network, and…

Machine Learning · Statistics 2017-07-18 David Belanger , Bishan Yang , Andrew McCallum

We present EPR-Net, a novel and effective deep learning approach that tackles a crucial challenge in biophysics: constructing potential landscapes for high-dimensional non-equilibrium steady-state (NESS) systems. EPR-Net leverages a nice…

Biological Physics · Physics 2024-04-10 Yue Zhao , Wei Zhang , Tiejun Li

Against the backdrop of increasingly severe global environmental changes, accurately predicting and meeting renewable energy demands has become a key challenge for sustainable business development. Traditional energy demand forecasting…

Machine Learning · Computer Science 2024-10-22 Te Li , Mengze Zhang , Yan Zhou

Determining the different conformational states of a protein and the transition paths between them is key to fully understanding the relationship between biomolecular structure and function. This can be accomplished by sampling protein…

Biological Physics · Physics 2021-03-24 Venkata K. Ramaswamy , Chris G. Willcocks , Matteo T. Degiacomi