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Uncertainty quantification (UQ) has become critical for evaluating the reliability of artificial intelligence systems, especially in medical image segmentation. This study addresses the interpretability of instance-wise uncertainty values…

Large Multimodal Models (LMMs), harnessing the complementarity among diverse modalities, are often considered more robust than pure Language Large Models (LLMs); yet do LMMs know what they do not know? There are three key open questions…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Ruiyang Zhang , Hu Zhang , Hao Fei , Zhedong Zheng

Most uncertainty quantification (UQ) approaches provide a single scalar value as a measure of model reliability. However, different uncertainty measures could provide complementary information on the prediction confidence. Even measures…

Large Language Models (LLMs) have become increasingly pervasive, finding applications across many industries and disciplines. Ensuring the trustworthiness of LLM outputs is paramount, where Uncertainty Estimation (UE) plays a key role. In…

Computation and Language · Computer Science 2025-11-06 Kevin Wang , Subre Abdoul Moktar , Jia Li , Kangshuo Li , Feng Chen

Large Language Models (LLMs) are known to hallucinate and generate non-factual outputs which can undermine user trust. Traditional methods to directly mitigate hallucinations, such as representation editing and contrastive decoding, often…

Machine Learning · Computer Science 2025-03-11 Prasenjit Dey , Srujana Merugu , Sivaramakrishnan Kaveri

This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

Large language models (LLMs) have delivered significant breakthroughs across diverse domains but can still produce unreliable or misleading outputs, posing critical challenges for real-world applications. While many recent studies focus on…

Computation and Language · Computer Science 2025-09-08 Yang Nan , Pengfei He , Ravi Tandon , Han Xu

Large language models (LLMs) have revolutionized the field of natural language processing with their impressive reasoning and question-answering capabilities. However, these models are sometimes prone to generating credible-sounding but…

Computation and Language · Computer Science 2026-04-21 Ranganath Krishnan , Piyush Khanna , Omesh Tickoo

Benchmarks shape progress in AI research. A useful benchmark should be both difficult and realistic: questions should challenge frontier models while also reflecting real-world usage. Yet, current paradigms face a difficulty-realism…

Large-language models (LLMs) and chatbot agents are known to provide wrong outputs at times, and it was recently found that this can never be fully prevented. Hence, uncertainty quantification plays a crucial role, aiming to quantify the…

Machine Learning · Computer Science 2025-05-29 Michael Kirchhof , Gjergji Kasneci , Enkelejda Kasneci

Large Language Models (LLMs) have demonstrated impressive capabilities in long-form generation, yet their application is hindered by the hallucination problem. While Uncertainty Quantification (UQ) is essential for assessing reliability,…

Computation and Language · Computer Science 2026-04-15 Guanran Luo , Wentao Qiu , Wanru Zhao , Wenhan Lv , Zhongquan Jian , Meihong Wang , Qingqiang Wu

Despite recent progress in systematic evaluation frameworks, benchmarking the uncertainty of large language models (LLMs) remains a highly challenging task. Existing methods for benchmarking the uncertainty of LLMs face three key…

Computation and Language · Computer Science 2025-06-05 Xunzhi Wang , Zhuowei Zhang , Gaonan Chen , Qiongyu Li , Bitong Luo , Zhixin Han , Haotian Wang , Zhiyu li , Hang Gao , Mengting Hu

As large language models become increasingly capable at various writing tasks, their weakness at generating unique and creative content becomes a major liability. Although LLMs have the ability to generate text covering diverse topics,…

Computation and Language · Computer Science 2025-08-12 Ramya Namuduri , Yating Wu , Anshun Asher Zheng , Manya Wadhwa , Greg Durrett , Junyi Jessy Li

As large language models (LLMs) are increasingly integrated into high-stakes decision-making, the ability to reliably quantify uncertainty has become a critical requirement for safety and trust. However, current uncertainty quantification…

Artificial Intelligence · Computer Science 2026-05-28 Seongjun Lee , Suwan Yoon , Changhee Lee

A model's ability to express its own predictive uncertainty is an essential attribute for maintaining clinical user confidence as computational biomarkers are deployed into real-world medical settings. In the domain of cancer digital…

Uncertainty quantification (UQ) in machine learning is currently drawing increasing research interest, driven by the rapid deployment of deep neural networks across different fields, such as computer vision, natural language processing, and…

Machine Learning · Computer Science 2022-08-26 Zongren Zou , Xuhui Meng , Apostolos F Psaros , George Em Karniadakis

Uncertainty estimation is crucial for the reliability of safety-critical human and artificial intelligence (AI) interaction systems, particularly in the domain of healthcare engineering. However, a robust and general uncertainty measure for…

Computation and Language · Computer Science 2024-11-19 Zhiyuan Wang , Jinhao Duan , Chenxi Yuan , Qingyu Chen , Tianlong Chen , Yue Zhang , Ren Wang , Xiaoshuang Shi , Kaidi Xu

Large language models (LLMs) produce outputs with varying levels of uncertainty, and, just as often, varying levels of correctness; making their practical reliability far from guaranteed. To quantify this uncertainty, we systematically…

Computation and Language · Computer Science 2025-10-24 Christian Hobelsberger , Theresa Winner , Andreas Nawroth , Oliver Mitevski , Anna-Carolina Haensch

The rapid advancement of large language model(LLM) technology has facilitated its integration into various domains of professional and daily life. However, the persistent challenge of LLM hallucination has emerged as a critical limitation,…

Computation and Language · Computer Science 2026-01-05 Yuhao Zhang , Zhongliang Yang , Linna Zhou

Machine learning methods are increasingly widely used in high-risk settings such as healthcare, transportation, and finance. In these settings, it is important that a model produces calibrated uncertainty to reflect its own confidence and…

Artificial Intelligence · Computer Science 2022-09-09 Sophia Sun