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Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

Quantitative Methods · Quantitative Biology 2022-12-01 Nir Gavish , Guy Katriel

Population heterogeneity, especially in individuals' contact networks, plays an important role in transmission dynamics of infectious diseases. For vaccine-preventable diseases, outstanding issues like vaccine hesitancy and availability of…

Populations and Evolution · Quantitative Biology 2022-12-29 Alina Glaubitz , Feng Fu

The Covid-19 pandemic revealed the difficulties of vaccinating a population under the circumstances marked by urgency and limited availability of doses while balancing benefits associated with distinct guidelines satisfying specific ethical…

Quantitative Methods · Quantitative Biology 2023-06-08 Pedro Ribeiro de Almeida , Vitor Hirata Sanches , Carla Goldman

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

Opposition to vaccination has long been a non-negligible public health phenomenon resulted from people's varied perceptions toward vaccination (e.g., vaccine-phobia). This paper investigates the voluntary vaccination behavior of a…

Physics and Society · Physics 2019-09-04 Liqun Lu , Yanfeng Ouyang

In this work, to support decision making of immunisation strategies, we propose the inclusion of two vaccination doses in the SEIR model considering a stochastic cellular automaton. We analyse three different scenarios of vaccination: $i)…

Spreading processes represent a very efficient tool to investigate the structural properties of networks and the relative importance of their constituents, and have been widely used to this aim in static networks. Here we consider simple…

Physics and Society · Physics 2013-09-11 Michele Starnini , Anna Machens , Ciro Cattuto , Alain Barrat , Romualdo Pastor Satorras

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, in many low and middle-income countries with geographically dispersed and nomadic populations, last-mile vaccine delivery can be extremely…

Applications · Statistics 2021-04-30 Yuwen Yang , Jayant Rajgopal

We present a stochastic epidemic model to study the effect of various preventive measures, such as uniform reduction of contacts and transmission, vaccination, isolation, screening and contact tracing, on a disease outbreak in a…

Populations and Evolution · Quantitative Biology 2022-07-08 Martina Favero , Gianpaolo Scalia Tomba , Tom Britton

There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often addressed using epidemic models, in…

Populations and Evolution · Quantitative Biology 2010-12-10 Thomas House , Matt J Keeling

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Most countries have started vaccinating people against COVID-19. However, due to limited production capacities and logistical challenges it will take months/years until herd immunity is achieved. Therefore, vaccination and social distancing…

Physics and Society · Physics 2021-04-22 Sara Grundel , Stefan Heyder , Thomas Hotz , Tobias K. S. Ritschel , Philipp Sauerteig , Karl Worthmann

Several recent studies have tackled the issue of optimal network immunization by providing efficient criteria to identify key nodes to be removed in order to break apart a network, thus preventing the occurrence of extensive epidemic…

Physics and Society · Physics 2018-02-22 Giovanni Strona , Claudio Castellano

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

Populations and Evolution · Quantitative Biology 2022-03-18 Qi Luo , Ryan Weightman , Sean T. McQuade , Mateo Diaz , Emmanuel Trélat , William Barbour , Dan Work , Samitha Samaranayake , Benedetto Piccoli

The paper describes a method to understand time required to vaccinate against viruses in total as well as subpopulations. As a demonstration, a model based estimate for time required to vaccinate H1N1 in India, given its administrative…

Quantitative Methods · Quantitative Biology 2021-06-15 Arni S. R. Srinivasa Rao , Thomas Kurien

Effective strategies of vaccine prioritization are essential to mitigate the impacts of severe infectious diseases. We investigate the role of infection fatality ratio (IFR) and social contact matrices on vaccination prioritization using a…

Populations and Evolution · Quantitative Biology 2023-10-04 Arthur Schulenburg , Wesley Cota , Guilherme S. Costa , Silvio C. Ferreira

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

The global SARS-CoV-2 (COVID-19) pandemic highlighted the challenge of equitable vaccine distribution between high- and low-income countries. Many high-income countries were reluctant or slow to distribute extra doses of the vaccine to…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

To mitigate the pandemic stemming from COVID-19, numerous nations have initiated extensive vaccination campaigns for their citizens since late 2020. While affluent countries have predominantly received vaccine allocations, fewer doses have…

Physics and Society · Physics 2024-04-01 Hsin-Ju Chou , Jing-Yuan Ko , Sung-Po Chao

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas