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Recent advances in Structure-based Drug Design (SBDD) have leveraged generative models for 3D molecular generation, predominantly evaluating model performance by binding affinity to target proteins. However, practical drug discovery…

Deep generative modeling to stochastically design small molecules is an emerging technology for accelerating drug discovery and development. However, one major issue in molecular generative models is their lower frequency of drug-like…

In semiconductor manufacturing, the wafer dicing process is central yet vulnerable to defects that significantly impair yield - the proportion of defect-free chips. Deep neural networks are the current state of the art in (semi-)automated…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Zhining Hu , Tobias Schlosser , Michael Friedrich , André Luiz Vieira e Silva , Frederik Beuth , Danny Kowerko

Anomaly detection in time series data, to identify points that deviate from normal behaviour, is a common problem in various domains such as manufacturing, medical imaging, and cybersecurity. Recently, Generative Adversarial Networks (GANs)…

Machine Learning · Computer Science 2025-05-27 Md Abul Bashar , Richi Nayak

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

Machine Learning · Computer Science 2025-03-12 Taojie Kuang , Qianli Ma , Athanasios V. Vasilakos , Yu Wang , Qiang , Cheng , Zhixiang Ren

The ability to predict the evolution of a pathogen would significantly improve the ability to control, prevent, and treat disease. Despite significant progress in other problem spaces, deep learning has yet to contribute to the issue of…

Quantitative Methods · Quantitative Biology 2020-08-28 Daniel S. Berman , Craig Howser , Thomas Mehoke , Jared D. Evans

Deep generative models, such as generative adversarial networks (GANs), are pivotal in discovering novel drug-like candidates via de novo molecular generation. However, traditional character-wise tokenizers often struggle with identifying…

Machine Learning · Computer Science 2024-10-01 Huidong Tang , Chen Li , Yasuhiko Morimoto

Deep neural networks (DNNs) have greatly contributed to the performance gains in semantic segmentation. Nevertheless, training DNNs generally requires large amounts of pixel-level labeled data, which is expensive and time-consuming to…

Computer Vision and Pattern Recognition · Computer Science 2023-01-02 Yonghao Xu , Fengxiang He , Bo Du , Dacheng Tao , Liangpei Zhang

Generative adversarial networks (GANs) have shown great success in applications such as image generation and inpainting. However, they typically require large datasets, which are often not available, especially in the context of prediction…

Machine Learning · Computer Science 2020-01-31 Daniel Stoller , Sebastian Ewert , Simon Dixon

Automatic modulation classification (AMC) using the Deep Neural Network (DNN) approach outperforms the traditional classification techniques, even in the presence of challenging wireless channel environments. However, the adversarial…

Machine Learning · Computer Science 2022-06-01 Eyad Shtaiwi , Ahmed El Ouadrhiri , Majid Moradikia , Salma Sultana , Ahmed Abdelhadi , Zhu Han

Adversarial examples pose many security threats to convolutional neural networks (CNNs). Most defense algorithms prevent these threats by finding differences between the original images and adversarial examples. However, the found…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Li Chen , Qi Li , Weiye Chen , Zeyu Wang , Haifeng Li

Generative adversarial networks (GANs) are one of the most robust and versatile techniques in the field of generative artificial intelligence. In this work, we report on an application of GANs in the domain of synthetic spectral data…

Molecular property prediction (e.g., energy) is an essential problem in chemistry and biology. Unfortunately, many supervised learning methods usually suffer from the problem of scarce labeled molecules in the chemical space, where such…

Machine Learning · Computer Science 2020-07-08 Zhongkai Hao , Chengqiang Lu , Zheyuan Hu , Hao Wang , Zhenya Huang , Qi Liu , Enhong Chen , Cheekong Lee

Generative Adversarial Networks (GAN) is a model for data synthesis, which creates plausible data through the competition of generator and discriminator. Although GAN application to image synthesis is extensively studied, it has inherent…

Computation and Language · Computer Science 2025-01-07 Jun-Min Lee , Tae-Bin Ha

Generative Adversarial Networks (GANs) can successfully approximate a probability distribution and produce realistic samples. However, open questions such as sufficient convergence conditions and mode collapse still persist. In this paper,…

Machine Learning · Computer Science 2019-03-13 Thang Doan , Joao Monteiro , Isabela Albuquerque , Bogdan Mazoure , Audrey Durand , Joelle Pineau , R Devon Hjelm

Weakly-supervised learning has become a popular technology in recent years. In this paper, we propose a novel medical image classification algorithm, called Weakly-Supervised Generative Adversarial Networks (WSGAN), which only uses a small…

Computer Vision and Pattern Recognition · Computer Science 2021-12-01 Jiawei Mao , Xuesong Yin , Yuanqi Chang , Qi Huang

Deep neural networks have been widely deployed in various machine learning tasks. However, recent works have demonstrated that they are vulnerable to adversarial examples: carefully crafted small perturbations to cause misclassification by…

Machine Learning · Computer Science 2019-03-01 Ke Sun , Zhanxing Zhu , Zhouchen Lin

We introduce BSD-GAN, a novel multi-branch and scale-disentangled training method which enables unconditional Generative Adversarial Networks (GANs) to learn image representations at multiple scales, benefiting a wide range of generation…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Zili Yi , Zhiqin Chen , Hao Cai , Wendong Mao , Minglun Gong , Hao Zhang

In this paper, we present a simple approach to train Generative Adversarial Networks (GANs) in order to avoid a \textit {mode collapse} issue. Implicit models such as GANs tend to generate better samples compared to explicit models that are…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Seyed Mehdi Iranmanesh , Nasser M. Nasrabadi

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr
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