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We propose a novel sparse dictionary learning method for planar shapes in the sense of Kendall, namely configurations of landmarks in the plane considered up to similitudes. Our shape dictionary method provides a good trade-off between…

Image and Video Processing · Electrical Eng. & Systems 2020-01-14 Anna Song , Virginie Uhlmann , Julien Fageot , Michael Unser

We investigate the addition of constraints on the function image and its derivatives for the incorporation of prior knowledge in symbolic regression. The approach is called shape-constrained symbolic regression and allows us to enforce e.g.…

Neural and Evolutionary Computing · Computer Science 2021-06-01 Gabriel Kronberger , Fabricio Olivetti de França , Bogdan Burlacu , Christian Haider , Michael Kommenda

The problem of finding a time-dependent vector field which warps an initial set of points to a target set is common in shape analysis. It is an example of a problem in the diffeomorphic shape matching regime, and can be thought of as a…

Optimization and Control · Mathematics 2025-08-12 Erik Jansson , Klas Modin

In this article, we consider the problem of few-shot learning for classification. We assume a network trained for base categories with a large number of training examples, and we aim to add novel categories to it that have only a few, e.g.,…

Machine Learning · Computer Science 2020-03-23 Hong-Gyu Jung , Seong-Whan Lee

The ability of oligonucleotide microarrays to measure gene expression has been hindered by an imperfect understanding of the relationship between input RNA concentrations and output signals. We argue that this relationship can be understood…

Biomolecules · Quantitative Biology 2007-05-23 J. M. Deutsch , Shoudan Liang , Onuttom Narayan

The algebraic approach to the Constraint Satisfaction Problem (CSP) uses high order symmetries of relational structures -- polymorphisms -- to study the complexity of the CSP. In this paper we further develop one of the methods the…

Logic in Computer Science · Computer Science 2020-07-21 Andrei A. Bulatov

A constrained multivariate linear model is a multivariate linear model with the columns of its coefficient matrix constrained to lie in a known subspace. This class of models includes those typically used to study growth curves and…

Methodology · Statistics 2021-01-05 Dennis Cook , Liliana Forzani , Lan Liu

Purpose: We perform anatomical landmarking for craniomaxillofacial (CMF) bones without explicitly segmenting them. Towards this, we propose a new simple yet efficient deep network architecture, called \textit{relational reasoning network…

Machine Learning · Computer Science 2022-09-20 Neslisah Torosdagli , Syed Anwar , Payal Verma , Denise K Liberton , Janice S. Lee , Wade W. Han , Ulas Bagci

Despite great interest in solving RNA secondary structures due to their impact on function, it remains an open problem to determine structure from sequence. Among experimental approaches, a promising candidate is the "chemical modification…

Quantitative Methods · Quantitative Biology 2011-06-30 Sharon Aviran , Julius B. Lucks , Lior Pachter

We present a framework for shape matching in computational anatomy allowing users control of the degree to which the matching is diffeomorphic. This control is given as a function defined over the image and parameterises the template…

Image and Video Processing · Electrical Eng. & Systems 2019-05-23 Andreas Bock , Alexis Arnaudon , Colin Cotter

RNA structure determination is essential for understanding its biological functions. However, the reconstruction process often faces challenges, such as atomic clashes, which can lead to inaccurate models. To address these challenges, we…

Biomolecules · Quantitative Biology 2026-03-04 Menghao Wu , Zhigang Yao

Multimodal models have demonstrated powerful capabilities in complex tasks requiring multimodal alignment, including zero-shot classification and cross-modal retrieval. However, existing models typically rely on millions of paired…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Fabian Gröger , Shuo Wen , Huyen Le , Maria Brbić

In recent years, the spectral analysis of appropriately defined kernel matrices has emerged as a principled way to extract the low-dimensional structure often prevalent in high-dimensional data. Here we provide an introduction to spectral…

Machine Learning · Statistics 2010-04-20 Mohamed-Ali Belabbas , Patrick J. Wolfe

In this paper, we propose a method to cluster multiple intersected manifolds. The algorithm chooses several landmark nodes randomly and then checks whether there is an angle constrained path between each landmark node and every other node…

Computer Vision and Pattern Recognition · Computer Science 2018-02-22 Amir Babaeian

DNA strings and their properties are widely studied since last 20 years due to its applications in DNA computing. In this area, one designs a set of DNA strings (called DNA code) which satisfies certain thermodynamic and combinatorial…

Information Theory · Computer Science 2025-10-03 Krishna Gopal Benerjee , Manish K Gupta

We introduce a model of thermalized conformations in space of RNA -or single stranded DNA- molecules, which includes the possibility of hairpin formation. This model contains the usual secondary structure information, but extends it to the…

Soft Condensed Matter · Physics 2007-05-23 Andrea Montanari , Marc Mezard

Since the advent of U-Net, fully convolutional deep neural networks and its many variants have completely changed the modern landscape of deep learning based medical image segmentation. However, the over dependence of these methods on pixel…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Simon Bohlender , Ilkay Oksuz , Anirban Mukhopadhyay

Two methods are proposed for high-dimensional shape-constrained regression and classification. These methods reshape pre-trained prediction rules to satisfy shape constraints like monotonicity and convexity. The first method can be applied…

Machine Learning · Statistics 2018-05-17 Matt Bonakdarpour , Sabyasachi Chatterjee , Rina Foygel Barber , John Lafferty

This contribution focuses on the fascinating RNA molecule, its sequence-dependent folding driven by base-pairing interactions, the interplay between these interactions and natural evolution, and its multiple regulatory roles. The four of us…

Statistical Mechanics · Physics 2022-07-28 Simona Cocco , Andrea De Martino , Andrea Pagnani , Martin Weigt

Confined thin structures are ubiquitous in nature. Spatial and length constraints have led to a number of novel packing strategies at both the micro-scale, as when DNA packages inside a capsid, and the macro-scale, seen in plant root…

Soft Condensed Matter · Physics 2019-11-28 David J. Schunter, , Regina K. Czech , Douglas P. Holmes