Related papers: Epilepsy and its driving forces: understanding the…
Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…
The mechanisms of psychotic symptoms like hallucinations and delusions are often investigated in fully-formed illness, well after symptoms emerge. These investigations have yielded key insights, but are not well-positioned to reveal the…
We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…
Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…
This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…
Hallucinations and delusions are often grouped together within the positive symptoms of psychosis. However, recent evidence suggests they may be driven by distinct computational and neural mechanisms. Examining the time course of their…
The study aims to investigate the similarities and differences in the brain damage caused by Hypoxia-Ischemia (HI), Hypoglycemia, and Epilepsy. Hypoglycemia poses a significant challenge in improving glycemic regulation for insulin-treated…
Excessively high, neural synchronisation has been associated with epileptic seizures, one of the most common brain diseases worldwide. A better understanding of neural synchronisation mechanisms can thus help control or even treat epilepsy.…
Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…
Since the manual detection of electrographic seizures in continuous electroencephalogram (EEG) monitoring is very time-consuming and requires a trained expert, attempts to develop automatic seizure detection are diverse and ongoing. Machine…
Recently Osorio et al (Eur. J. Neurosci., 30 (2009) 1554) reported that probability distribution of intervals between successive epileptic seizures follows a power law with exponent 1.5. We theoretically explain this finding by modeling…
Epilepsy is one of the most common neurological disorders that can be diagnosed through electroencephalogram (EEG), in which the following epileptic events can be observed: pre-ictal, ictal, post-ictal, and interictal. In this paper, we…
Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…
Epilepsy is one of the most common neurological diseases, characterized by transient and unprovoked events called epileptic seizures. Electroencephalogram (EEG) is an auxiliary method used to perform both the diagnosis and the monitoring of…
An Electroencephalogram (EEG) is a non-invasive exam that records the brain's electrical activity. This is used to help diagnose conditions such as different brain problems. EEG signals are taken for epilepsy detection, and with Discrete…
Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…
Objective: The aim of this study is to develop an efficient and reliable epileptic seizure prediction system using intracranial EEG (iEEG) data, especially for people with drug-resistant epilepsy. The prediction procedure should yield…
Amyloid fibrillation is a protein self-assembly phenomenon that is intimately related to well-known human neurodegenerative diseases. During the past few decades, striking advances have been achieved in our understanding of the physical…
Social media platforms, particularly Reddit's r/Epilepsy community, offer a unique perspective into the experiences of individuals with epilepsy (PWE) and their caregivers. This study analyzes 57k posts and 533k comments to explore key…
Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and…