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The successes of foundation models such as ChatGPT and AlphaFold have spurred significant interest in building similar models for electronic medical records (EMRs) to improve patient care and hospital operations. However, recent hype has…

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Federated learning (FL) has become a promising paradigm for collaborative medical image analysis, yet existing frameworks remain tightly coupled to task-specific backbones and are fragile under heterogeneous imaging modalities. Such…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Meilin Liu , Jiaying Wang , Jing Shan

Longitudinal medical report generation is clinically important yet remains challenging due to strict privacy constraints and the evolving nature of disease progression. Although federated learning (FL) enables collaborative training without…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 He Zhu , Ren Togo , Takahiro Ogawa , Kenji Hirata , Minghui Tang , Takaaki Yoshimura , Hiroyuki Sugimori , Noriko Nishioka , Yukie Shimizu , Kohsuke Kudo , Miki Haseyama

Machine learning on large-scale genomic or transcriptomic data is important for many novel health applications. For example, precision medicine tailors medical treatments to patients on the basis of individual biomarkers, cellular and…

Machine Learning · Computer Science 2025-05-26 Anika Hannemann , Jan Ewald , Leo Seeger , Erik Buchmann

Improving the fairness of federated learning (FL) benefits healthy and sustainable collaboration, especially for medical applications. However, existing fair FL methods ignore the specific characteristics of medical FL applications, i.e.,…

Machine Learning · Computer Science 2024-10-29 Yunlu Yan , Lei Zhu , Yuexiang Li , Xinxing Xu , Rick Siow Mong Goh , Yong Liu , Salman Khan , Chun-Mei Feng

Centralized RAG pipelines struggle with heterogeneous and privacy-sensitive data, especially in distributed healthcare settings where patient data spans SQL, knowledge graphs, and clinical notes. Clinicians face difficulties retrieving rare…

Artificial Intelligence · Computer Science 2025-09-09 Cheng Qian , Hainan Zhang , Yongxin Tong , Hong-Wei Zheng , Zhiming Zheng

Legacy Electronic Health Records (EHRs) systems were not developed with the level of connectivity expected from them nowadays. Therefore, interoperability weakness inherent in the legacy systems can result in poor patient care and waste of…

Software Engineering · Computer Science 2018-08-24 Yilong Yang , Xiaoshan Li , Nafees Qamar , Wei Ke , Zhiming Liu

Foundation Models (FMs), such as OpenAI's GPT, are fundamentally transforming the practice of software engineering by enabling the development of \emph{FMware} -- applications and infrastructures built around these models. FMware systems…

Software Engineering · Computer Science 2025-10-14 Zitao Wang , Zhimin Zhao , Michael W. Godfrey

Segmentation models for brain lesions in MRI are typically developed for a specific disease and trained on data with a predefined set of MRI modalities. Such models cannot segment the disease using data with a different set of MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Felix Wagner , Wentian Xu , Pramit Saha , Ziyun Liang , Daniel Whitehouse , David Menon , Virginia Newcombe , Natalie Voets , J. Alison Noble , Konstantinos Kamnitsas

Multimodal federated learning holds immense potential for collaboratively training models from multiple sources without sharing raw data, addressing both data scarcity and privacy concerns, two key challenges in healthcare. A major…

Machine Learning · Computer Science 2025-05-27 Pranav Poudel , Aavash Chhetri , Prashnna Gyawali , Georgios Leontidis , Binod Bhattarai

Federated Learning enables decentralized training by aggregating model updates across clients without sharing raw data, while Split Federated Learning further partitions the model between clients and a server to reduce computation and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Chamani Shiranthika , Hadi Hadizadeh , Parvaneh Saeedi

Developing predictive modelling solutions for risk estimation is extremely challenging in health-care informatics. Risk estimation involves integration of heterogeneous clinical sources having different representation from different…

Machine Learning · Computer Science 2016-09-30 Priyanka H U , Vivek R

The real-world implementation of federated learning is complex and requires research and development actions at the crossroad between different domains ranging from data science, to software programming, networking, and security. While…

Universal medical image segmentation models have emerged as a promising paradigm due to their strong generalizability across diverse tasks, showing great potential for a wide range of clinical applications. This potential has been partly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Yanwu Yang , Guinan Su , Jiesi Hu , Francesco Sammarco , Jonas Geiping , Thomas Wolfers

Inefficient healthcare is a major concern among many African nations and can be mitigated by building world-class infrastructure connecting different medical facilities for collaboration and resource sharing. Such infrastructure should…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-06 Olasupo O. Ajayi , Antoine B. Bagula , Kun Ma

Multi-center survival prediction can improve robustness and generalizability, yet privacy regulations and institutional governance often prevent pooling patient-level clinical and genomic data across institutions. In practice, deployment is…

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

Federated learning enables multiple hospitals to cooperatively learn a shared model without privacy disclosure. Existing methods often take a common assumption that the data from different hospitals have the same modalities. However, such a…

Image and Video Processing · Electrical Eng. & Systems 2023-06-06 Yunlu Yan , Hong Wang , Yawen Huang , Nanjun He , Lei Zhu , Yuexiang Li , Yong Xu , Yefeng Zheng