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The progress of humanity is driven by those successful discoveries accompanied by countless failed experiments. Researchers often seek the potential research directions by reading and then verifying them through experiments. The process…

Artificial Intelligence · Computer Science 2024-07-31 Haotian Chen , Xinjie Shen , Zeqi Ye , Wenjun Feng , Haoxue Wang , Xiao Yang , Xu Yang , Weiqing Liu , Jiang Bian

LLMs have made significant progress in complex but easy-to-verify problems, yet they still struggle with discovering the unknown. In this paper, we present \textbf{AlphaResearch}, an autonomous research agent designed to discover new…

Computation and Language · Computer Science 2026-04-02 Zhaojian Yu , Kaiyue Feng , Yilun Zhao , Shilin He , Xiao-Ping Zhang , Arman Cohan

The advent of AI driven large language models (LLMs) have stirred discussions about their role in qualitative research. Some view these as tools to enrich human understanding, while others perceive them as threats to the core values of the…

Software Engineering · Computer Science 2023-06-26 Muneera Bano , Didar Zowghi , Jon Whittle

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Large Language Models (LLMs) are increasingly used for clinical decision support, where hallucinations and unsafe suggestions may pose direct risks to patient safety. These risks are hard to assess: subtle clinical errors are often missed…

Computation and Language · Computer Science 2026-05-14 Yinzhu Chen , Abdine Maiga , Hossein A. Rahmani , Emine Yilmaz

This paper investigates the ability of large language models (LLMs) to solve statistical tasks, as well as their capacity to assess the quality of reasoning. While state-of-the-art LLMs have demonstrated remarkable performance in a range of…

Computation and Language · Computer Science 2026-01-22 Crish Nagarkar , Leonid Bogachev , Serge Sharoff

The rapid advancement of large language models (LLMs) has driven the development of agentic systems capable of autonomously performing complex tasks. Despite their impressive capabilities, LLMs remain constrained by their internal knowledge…

Information Retrieval · Computer Science 2025-08-19 Wenlin Zhang , Xiaopeng Li , Yingyi Zhang , Pengyue Jia , Yichao Wang , Huifeng Guo , Yong Liu , Xiangyu Zhao

As Large Language Models (LLMs) transition from static tools to autonomous agents, traditional evaluation benchmarks that measure performance on downstream tasks are becoming insufficient. These methods fail to capture the emergent social…

Artificial Intelligence · Computer Science 2025-10-03 Zarreen Reza

In many scientific fields, large language models (LLMs) have revolutionized the way text and other modalities of data (e.g., molecules and proteins) are handled, achieving superior performance in various applications and augmenting the…

Computation and Language · Computer Science 2024-10-01 Yu Zhang , Xiusi Chen , Bowen Jin , Sheng Wang , Shuiwang Ji , Wei Wang , Jiawei Han

Large language models (LLMs) have exhibited exceptional capabilities in natural language understanding and generation, image recognition, and multimodal tasks, charting a course towards AGI and emerging as a central issue in the global…

Computation and Language · Computer Science 2025-11-20 Guoqiang Liang , Jingqian Gong , Mengxuan Li , Gege Lin , Shuo Zhang

Large Language Models (LLMs) have shown remarkable capabilities in solving diverse tasks. However, their proficiency in iteratively optimizing complex solutions through learning from previous feedback remains insufficiently explored. To…

Artificial Intelligence · Computer Science 2025-06-13 Xiaozhe Li , Jixuan Chen , Xinyu Fang , Shengyuan Ding , Haodong Duan , Qingwen Liu , Kai Chen

In this paper, we describe the capabilities and constraints of Large Language Models (LLMs) within disparate academic disciplines, aiming to delineate their strengths and limitations with precision. We examine how LLMs augment scientific…

The increasing prevalence of online misinformation has heightened the demand for automated fact-checking solutions. Large Language Models (LLMs) have emerged as potential tools for assisting in this task, but their effectiveness remains…

Computers and Society · Computer Science 2025-03-10 Nicolo' Fontana , Francesco Corso , Enrico Zuccolotto , Francesco Pierri

Large language models (LLMs) excel across many natural language processing tasks but face challenges in domain-specific, analytical tasks such as conducting research surveys. This study introduces ResearchArena, a benchmark designed to…

Artificial Intelligence · Computer Science 2025-09-09 Hao Kang , Chenyan Xiong

As language models (LMs) evolve from chat assistants to long-horizon agents capable of multi-step reasoning and tool use, existing benchmarks remain largely confined to structured or exam-style tasks that fall short of real-world…

Large Language Models (LLMs) have shown remarkable capabilities as autonomous agents, yet existing benchmarks either focus on single-agent tasks or are confined to narrow domains, failing to capture the dynamics of multi-agent coordination…

Multiagent Systems · Computer Science 2025-03-05 Kunlun Zhu , Hongyi Du , Zhaochen Hong , Xiaocheng Yang , Shuyi Guo , Zhe Wang , Zhenhailong Wang , Cheng Qian , Xiangru Tang , Heng Ji , Jiaxuan You

Active learning (AL) accelerates scientific discovery by prioritizing the most informative experiments, but traditional machine learning (ML) models used in AL suffer from cold-start limitations and domain-specific feature engineering,…

Machine Learning · Computer Science 2025-12-05 Hongchen Wang , Rafael Espinosa Castañeda , Jay R. Werber , Yao Fehlis , Edward Kim , Jason Hattrick-Simpers

Large Language Models (LLMs) have achieved significant advances in natural language processing, yet their potential for high-stake political decision-making remains largely unexplored. This paper addresses the gap by focusing on the…

Computation and Language · Computer Science 2026-01-26 Yueqing Liang , Liangwei Yang , Chen Wang , Congying Xia , Rui Meng , Xiongxiao Xu , Haoran Wang , Ali Payani , Kai Shu

Scientific literature is growing exponentially, creating a critical bottleneck for researchers to efficiently synthesize knowledge. While general-purpose Large Language Models (LLMs) show potential in text processing, they often fail to…

Computation and Language · Computer Science 2025-09-11 Fengyu She , Nan Wang , Hongfei Wu , Ziyi Wan , Jingmian Wang , Chang Wang

With the continuous evolution and refinement of LLMs, they are endowed with impressive logical reasoning or vertical thinking capabilities. But can they think out of the box? Do they possess proficient lateral thinking abilities? Following…

Computation and Language · Computer Science 2024-03-19 Shulin Huang , Shirong Ma , Yinghui Li , Mengzuo Huang , Wuhe Zou , Weidong Zhang , Hai-Tao Zheng