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Kinetic modeling enables \textit{in vivo} quantification of tracer uptake and glucose metabolism in [${}^{18}$F]Fluorodeoxyglucose ([${}^{18}$F]FDG) dynamic positron emission tomography (dPET) imaging of mice. However, kinetic modeling…

Quantitative Methods · Quantitative Biology 2025-10-27 Christian Salomonsen , Kristoffer K. Wickstrøm , Samuel Kuttner , Elisabeth Wetzer

Physics-informed Neural Networks (PINNs) is a method for numerical simulation that incorporates a loss function corresponding to the governing equations into a neural network. While PINNs have been explored for their utility in inverse…

Sound · Computer Science 2024-06-18 Kazuya Yokota , Masataka Ogura , Masajiro Abe

The thesis focuses on various techniques to find an alternate approximation method that could be universally used for a wide range of CFD problems but with low computational cost and low runtime. Various techniques have been explored within…

Machine Learning · Computer Science 2021-11-05 Siddharth Rout , Vikas Dwivedi , Balaji Srinivasan

This work is concerned with discovering the governing partial differential equation (PDE) of a physical system. Existing methods have demonstrated the PDE identification from finite observations but failed to maintain satisfying results…

Numerical Analysis · Mathematics 2023-02-09 Pongpisit Thanasutives , Takashi Morita , Masayuki Numao , Ken-ichi Fukui

The development of biophysical models for clinical applications is rapidly advancing in the research community, thanks to their predictive nature and their ability to assist the interpretation of clinical data. However, high-resolution and…

Physics-informed machine learning (PIML) integrates prior physical information, often in the form of differential equation constraints, into the process of fitting machine learning models to physical data. Popular PIML approaches, including…

Machine Learning · Statistics 2025-10-31 Mara Daniels , Liam Hodgkinson , Michael Mahoney

We are delighted to see the recent development of physics-informed extreme learning machine (PIELM) for its higher computational efficiency and accuracy compared to other physics-informed machine learning (PIML) paradigms. Since a…

Machine Learning · Computer Science 2025-11-04 He Yang , Fei Ren , Francesco Calabro , Hai-Sui Yu , Xiaohui Chen , Pei-Zhi Zhuang

Quantum Fisher Information (QFI) sets the ultimate precision limit for parameter estimation and is therefore a central quantity in quantum metrology. In time-dependent many-body systems, however, maximizing QFI is a highly non-trivial task…

We review four types of algorithms for physics-informed machine learning (PIML) inversion of geophysical data. The unifying equation is given by the joint objective function $\epsilon$: \begin{eqnarray} \epsilon^{||-PIML}&=&\lambda_1…

Geophysics · Physics 2023-10-13 Gerard T. Schuster , Shihang Feng

Physics-informed neural networks (PINNs) constitute a flexible approach to both finding solutions and identifying parameters of partial differential equations. Most works on the topic assume noiseless data, or data contaminated with weak…

Machine Learning · Statistics 2024-06-21 Philipp Pilar , Niklas Wahlström

Modeling tumor growth accurately is essential for understanding cancer progression and informing treatment strategies. To estimate the parameters in the tumor growth model described by a nonlinear PDE, we adopt Physics-Informed Neural…

Analysis of PDEs · Mathematics 2025-11-21 Liu Liu , Yifei Wang , Qinyu Xu , Xiaoqian Xu

Physics-informed neural networks (PINNs) provide a deep learning framework for numerically solving partial differential equations (PDEs), and have been widely used in a variety of PDE problems. However, there still remain some challenges in…

Machine Learning · Computer Science 2022-05-19 Wensheng Li , Chao Zhang , Chuncheng Wang , Hanting Guan , Dacheng Tao

Physics-Informed Neural Networks present a novel approach in SciML that integrates physical laws in the form of partial differential equations directly into the NN through soft constraints in the loss function. This work studies the…

Neural and Evolutionary Computing · Computer Science 2026-02-17 Suhas Suresh Bharadwaj , Reuben Thomas Thovelil

Physics-Infused Machine Learning (PIML) architectures aim at integrating machine learning with computationally-efficient, low-fidelity (partial) physics models, leading to improved generalizability, extrapolability, and robustness to noise,…

Computational Engineering, Finance, and Science · Computer Science 2022-01-19 Rayhaan Iqbal , Amir Behjat , Revant Adlakha , Jesse Callanan , Mostafa Nouh , Souma Chowdhury

This paper introduces a novel approach to solve inverse problems by leveraging deep learning techniques. The objective is to infer unknown parameters that govern a physical system based on observed data. We focus on scenarios where the…

Machine Learning · Computer Science 2023-10-02 Sidney Besnard , Frédéric Jurie , Jalal M. Fadili

Physics-informed machine learning (PIML) integrates partial differential equations (PDEs) into machine learning models to solve inverse problems, such as estimating coefficient functions (e.g., the Hamiltonian function) that characterize…

Computational Physics · Physics 2025-11-07 Yoh-ichi Mototake , Makoto Sasaki

Accurate temperature estimation of pouch cells with indirect liquid cooling is essential for optimizing battery thermal management systems for transportation electrification. However, it is challenging due to the computational expense of…

Machine Learning · Computer Science 2026-04-17 Zheng Liu

Complex optimal design and control processes often require repeated evaluations of expensive objective functions and consist of large design spaces. Data-driven surrogates such as neural networks and Gaussian processes provide an attractive…

Computational Engineering, Finance, and Science · Computer Science 2023-07-10 Manaswin Oddiraju , Divyang Amin , Michael Piedmonte , Souma Chowdhury

Physics-Informed Neural Networks (PINNs) have advanced the data-driven solution of differential equations (DEs) in dynamic physical systems, yet challenges remain in explainability, scalability, and architectural complexity. This paper…

Signal Processing · Electrical Eng. & Systems 2025-12-03 Ibrahim Shahbaz , Mohammad J. Abdel-Rahman , Eman Hammad

One use case of ``physics-informed neural networks'' (PINNs) is solution reconstruction, which aims to estimate the full-field state of a physical system from sparse measurements. Parameterized governing equations of the system are used in…

Computational Engineering, Finance, and Science · Computer Science 2025-05-09 Conor Rowan , Kurt Maute , Alireza Doostan