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Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Davide Evangelista , Pasquale Cascarano , Elena Loli Piccolomini

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

Recent advances in diffusion models have demonstrated exceptional performance in generative tasks across vari-ous fields. In positron emission tomography (PET), the reduction in tracer dose leads to information loss in sino-grams. Using…

Machine Learning · Computer Science 2024-11-11 Xingyu Ai , Bin Huang , Fang Chen , Liu Shi , Binxuan Li , Shaoyu Wang , Qiegen Liu

We present a supervised learning framework of training generative models for density estimation. Generative models, including generative adversarial networks, normalizing flows, variational auto-encoders, are usually considered as…

Machine Learning · Computer Science 2023-10-24 Yanfang Liu , Minglei Yang , Zezhong Zhang , Feng Bao , Yanzhao Cao , Guannan Zhang

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu

We present SURE-Score: an approach for learning score-based generative models using training samples corrupted by additive Gaussian noise. When a large training set of clean samples is available, solving inverse problems via score-based…

Machine Learning · Computer Science 2025-04-23 Asad Aali , Marius Arvinte , Sidharth Kumar , Jonathan I. Tamir

Diffusion models have emerged as the new state-of-the-art generative model with high quality samples, with intriguing properties such as mode coverage and high flexibility. They have also been shown to be effective inverse problem solvers,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Hyungjin Chung , Dohoon Ryu , Michael T. McCann , Marc L. Klasky , Jong Chul Ye

Diffusion models represent a class of generative models that produce data by denoising a sample corrupted by white noise. Despite the success of diffusion models in computer vision, audio synthesis, and point cloud generation, so far they…

Statistical Mechanics · Physics 2025-01-17 Kanta Masuki , Yuto Ashida

Discrete-time diffusion-based generative models and score matching methods have shown promising results in modeling high-dimensional image data. Recently, Song et al. (2021) show that diffusion processes that transform data into noise can…

Machine Learning · Computer Science 2021-10-01 Chin-Wei Huang , Jae Hyun Lim , Aaron Courville

Diffusion models have recently emerged as powerful priors for solving inverse problems. While computed tomography (CT) is theoretically a linear inverse problem, it poses many practical challenges. These include correlated noise, artifact…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Jiayang Shi , Daniel M. Pelt , K. Joost Batenburg

Low-dose computed tomography (CT) images suffer from noise and artifacts due to photon starvation and electronic noise. Recently, some works have attempted to use diffusion models to address the over-smoothness and training instability…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Hongming Shan

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

We propose a framework to perform Bayesian inference using conditional score-based diffusion models to solve a class of inverse problems in mechanics involving the inference of a specimen's spatially varying material properties from noisy…

Recently, score-based diffusion models have shown satisfactory performance in MRI reconstruction. Most of these methods require a large amount of fully sampled MRI data as a training set, which, sometimes, is difficult to acquire in…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Zhuo-Xu Cui , Chentao Cao , Shaonan Liu , Qingyong Zhu , Jing Cheng , Haifeng Wang , Yanjie Zhu , Dong Liang

We propose self-diffusion, a novel framework for solving inverse problems without relying on pretrained generative models. Traditional diffusion-based approaches require training a model on a clean dataset to learn to reverse the forward…

Machine Learning · Computer Science 2025-12-09 Guanxiong Luo , Shoujin Huang , Yanlong Yang

Recently, research on denoising diffusion models has expanded its application to the field of image restoration. Traditional diffusion-based image restoration methods utilize degraded images as conditional input to effectively guide the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Zhenning Shi , Haoshuai Zheng , Chen Xu , Changsheng Dong , Bin Pan , Xueshuo Xie , Along He , Tao Li , Huazhu Fu

Diffusion models are powerful tools for sampling from high-dimensional distributions by progressively transforming pure noise into structured data through a denoising process. When equipped with a guidance mechanism, these models can also…

Machine Learning · Computer Science 2026-05-04 Saeed Mohseni-Sehdeh , Walid Saad , Kei Sakaguchi , Tao Yu

Recovering signals from low-order moments is a fundamental yet notoriously difficult task in inverse problems. This recovery process often reduces to solving ill-conditioned systems of polynomial equations. In this work, we propose a new…

Signal Processing · Electrical Eng. & Systems 2025-09-16 Rafi Beinhorn , Shay Kreymer , Amnon Balanov , Michael Cohen , Alon Zabatani , Tamir Bendory

Diffusion models are widely used for generative tasks across domains. Given a pre-trained diffusion model, it is often desirable to fine-tune it further either to correct for errors in learning or to align with downstream applications.…