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Trustworthiness and transparency are essential for the clinical adoption of artificial intelligence (AI) in healthcare and biomedical research. Recent deep research systems aim to accelerate evidence-grounded scientific discovery by…

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

Human coders assign standardized medical codes to clinical documents generated during patients' hospitalization, which is error-prone and labor-intensive. Automated medical coding approaches have been developed using machine learning…

Computation and Language · Computer Science 2022-09-13 Wei Sun , Shaoxiong Ji , Erik Cambria , Pekka Marttinen

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

The era of big data has made vast amounts of clinical data readily available, particularly in the form of electronic health records (EHRs), which provides unprecedented opportunities for developing data-driven diagnostic tools to enhance…

Machine Learning · Computer Science 2025-03-06 Zekai Wang , Tieming Liu , Bing Yao

The convolutional-based methods provide good segmentation performance in the medical image segmentation task. However, those methods have the following challenges when dealing with the edges of the medical images: (1) Previous…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Jinkai Lv , Yuyong Hu , Quanshui Fu , Zhiwang Zhang , Yuqiang Hu , Lin Lv , Guoqing Yang , Jinpeng Li , Yi Zhao

Electronic medical records (EMRs), particularly in neurology, are inherently heterogeneous, sparse, and noisy, which poses significant challenges for large language models (LLMs) in clinical diagnosis. In such settings, single-agent systems…

Artificial Intelligence · Computer Science 2026-04-30 Shaowei Shen , Xiaohong Yang , Jie Yang , Lianfen Huang , Yongcai Zhang , Yang Zou , Seyyedali Hosseinalipour

Medical coding translates clinical documentation into standardized codes for billing, research, and public health, but manual coding is time-consuming and error-prone. Existing automation efforts rely on small datasets that poorly represent…

Recent advances in multimodal ECG representation learning center on aligning ECG signals with paired free-text reports. However, suboptimal alignment persists due to the complexity of medical language and the reliance on a full 12-lead…

Machine Learning · Computer Science 2025-02-26 Che Liu , Cheng Ouyang , Zhongwei Wan , Haozhe Wang , Wenjia Bai , Rossella Arcucci

Neurobiological and neurodegenerative diseases are inherently multifactorial, arising from coupled influences spanning genetic susceptibility, brain alterations, and environmental and behavioral factors. Multimodal modeling has therefore…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Shaowen Wan , Yanjun Lv , Lu Zhang , Dajiang Zhu , Bharat Biswal , Tianming Liu , Xiaobo Li , Lin Zhao

We propose a novel and interpretable embedding method to represent the international statistical classification codes of diseases and related health problems (i.e., ICD codes). This method considers a self-attention mechanism within the…

Applications · Statistics 2019-06-14 Dixin Luo , Hongteng Xu , Lawrence Carin

Traditional Chinese Medicine (TCM), as an effective alternative medicine, has been receiving increasing attention. In recent years, the rapid development of large language models (LLMs) tailored for TCM has highlighted the urgent need for…

Computation and Language · Computer Science 2025-10-28 Jiacheng Xie , Yang Yu , Ziyang Zhang , Shuai Zeng , Jiaxuan He , Ayush Vasireddy , Xiaoting Tang , Congyu Guo , Lening Zhao , Congcong Jing , Guanghui An , Dong Xu

Electrocardiogram (ECG) analysis is a fundamental tool for diagnosing cardiovascular conditions, yet anomaly detection in ECG signals remains challenging due to their inherent complexity and variability. We propose Multi-scale Masked…

Machine Learning · Computer Science 2025-02-11 Ya Zhou , Yujie Yang , Jianhuang Gan , Xiangjie Li , Jing Yuan , Wei Zhao

Multimodal Question Answering (MMQA) is crucial as it enables comprehensive understanding and accurate responses by integrating insights from diverse data representations such as tables, charts, and text. Most existing researches in MMQA…

Computation and Language · Computer Science 2024-10-30 Bowen Zhao , Tianhao Cheng , Yuejie Zhang , Ying Cheng , Rui Feng , Xiaobo Zhang

Chinese Spelling Correction (CSC) is gaining increasing attention due to its promise of automatically detecting and correcting spelling errors in Chinese texts. Despite its extensive use in many applications, like search engines and optical…

Computation and Language · Computer Science 2022-10-24 Wangjie Jiang , Zhihao Ye , Zijing Ou , Ruihui Zhao , Jianguang Zheng , Yi Liu , Siheng Li , Bang Liu , Yujiu Yang , Yefeng Zheng

To automatically correct handwritten assignments, the traditional approach is to use an OCR model to recognize characters and compare them to answers. The OCR model easily gets confused on recognizing handwritten Chinese characters, and the…

Computation and Language · Computer Science 2022-09-19 Yusen Zhang , Zhongli Li , Qingyu Zhou , Ziyi Liu , Chao Li , Mina Ma , Yunbo Cao , Hongzhi Liu

The use of International Classification of Diseases (ICD) codes in healthcare presents a challenge in selecting relevant codes as features for machine learning models due to this system's large number of codes. In this study, we compared…

Machine Learning · Computer Science 2024-10-29 Peyman Ghasemi , Joon Lee
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