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Generative AI increasingly supports scientific inference, from protein structure prediction to weather forecasting. Yet its distinctive failure mode, hallucination, raises epistemic alarm bells. I argue that this failure mode can be…

Computers and Society · Computer Science 2026-01-14 Charles Rathkopf

Medical question answering (QA) requires extensive access to domain-specific knowledge. A promising direction is to enhance large language models (LLMs) with external knowledge retrieved from medical corpora or parametric knowledge stored…

Computation and Language · Computer Science 2025-10-22 Lei Li , Xiao Zhou , Yingying Zhang , Xian Wu

Large language models (LLMs) have achieved remarkable success in various domains, primarily due to their strong capabilities in reasoning and generating human-like text. Despite their impressive performance, LLMs are susceptible to…

Cryptography and Security · Computer Science 2025-05-13 Yangguang Shao , Xinjie Lin , Haozheng Luo , Chengshang Hou , Gang Xiong , Jiahao Yu , Junzheng Shi

Retrieval augmented generation (RAG) is frequently used to mitigate hallucinations and provide up-to-date knowledge for large language models (LLMs). However, given that document retrieval is an imprecise task and sometimes results in…

Computation and Language · Computer Science 2025-02-10 Kevin Wu , Eric Wu , James Zou

While Large Language Models have transformed how we interact with AI systems, they suffer from a critical flaw: they confidently generate false information that sounds entirely plausible. This hallucination problem has become a major…

Artificial Intelligence · Computer Science 2025-10-28 Piyushkumar Patel

Although people are impressed by the content generation skills of large language models, the use of LLMs, such as ChatGPT, is limited by the domain grounding of the content. The correctness and groundedness of the generated content need to…

Computation and Language · Computer Science 2024-12-23 Xiaofeng Zhu , Jaya Krishna Mandivarapu

Retrieval-augmented generation (RAG) relies on retrieved context to guide large language models (LLM), yet treats retrieval as a weak heuristic rather than verifiable evidence -- leading to unsupported answers, hallucinations, and reliance…

Computation and Language · Computer Science 2026-02-02 Björn Deiseroth , Max Henning Höth , Kristian Kersting , Letitia Parcalabescu

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Large Language Models (LLMs) showcase impressive capabilities but encounter challenges like hallucination, outdated knowledge, and non-transparent, untraceable reasoning processes. Retrieval-Augmented Generation (RAG) has emerged as a…

Computation and Language · Computer Science 2024-03-28 Yunfan Gao , Yun Xiong , Xinyu Gao , Kangxiang Jia , Jinliu Pan , Yuxi Bi , Yi Dai , Jiawei Sun , Meng Wang , Haofen Wang

Large Language Models (LLMs) have exhibited remarkable proficiency in natural language understanding, prompting extensive exploration of their potential applications across diverse domains. In the medical domain, open-source LLMs have…

Computation and Language · Computer Science 2024-08-01 Cui Long , Yongbin Liu , Chunping Ouyang , Ying Yu

Retrieval-Augmented Generation RAG systems enhance large language models by grounding responses in external knowledge bases, but conventional RAG architectures operate with static corpora that cannot evolve from user interactions. We…

Artificial Intelligence · Computer Science 2025-12-30 Teja Chinthala

Retrieval-Augmented Generation (RAG) has gained significant attention in recent years for its potential to enhance natural language understanding and generation by combining large-scale retrieval systems with generative models. RAG…

Computation and Language · Computer Science 2025-03-18 Mingyue Cheng , Yucong Luo , Jie Ouyang , Qi Liu , Huijie Liu , Li Li , Shuo Yu , Bohou Zhang , Jiawei Cao , Jie Ma , Daoyu Wang , Enhong Chen

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Electronic health records (EHRs) are long, noisy, and often redundant, posing a major challenge for the clinicians who must navigate them. Large language models (LLMs) offer a promising solution for extracting and reasoning over this…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Dmitriy Dligach , Timothy A. Miller , Samantha Barr , Yanjun Gao , Matthew Churpek , Anoop Mayampurath , Majid Afshar

Evidence-based medicine promises to improve the quality of healthcare by empowering medical decisions and practices with the best available evidence. The rapid growth of medical evidence, which can be obtained from various sources, poses a…

Regulatory compliance in the pharmaceutical industry entails navigating through complex and voluminous guidelines, often requiring significant human resources. To address these challenges, our study introduces a chatbot model that utilizes…

Computation and Language · Computer Science 2024-02-07 Jaewoong Kim , Moohong Min

Conversational recommender systems have attracted immense attention recently. The most recent approaches rely on neural models trained on recorded dialogs between humans, implementing an end-to-end learning process. These systems are…

Information Retrieval · Computer Science 2022-05-26 Ahtsham Manzoor , Dietmar Jannach

Asthma rates have risen globally, driven by environmental and lifestyle factors. Access to immediate medical care is limited, particularly in developing countries, necessitating automated support systems. Large Language Models like ChatGPT…

Artificial Intelligence · Computer Science 2024-09-25 Adil Bahaj , Mounir Ghogho

Connecting conversation with external domain knowledge is vital for conversational recommender systems (CRS) to correctly understand user preferences. However, existing solutions either require domain-specific engineering, which limits…

Information Retrieval · Computer Science 2025-09-29 Dayu Yang , Hui Fang