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Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

The rapid advancement of large language models (LLMs) has significantly impacted various domains, including healthcare and biomedicine. However, the phenomenon of hallucination, where LLMs generate outputs that deviate from factual accuracy…

Computation and Language · Computer Science 2024-08-27 Duy Khoa Pham , Bao Quoc Vo

Retrieval-Augmented Generation (RAG) systems offer a powerful approach to enhancing large language model (LLM) outputs by incorporating fact-checked, contextually relevant information. However, fairness and reliability concerns persist, as…

Human-Computer Interaction · Computer Science 2025-04-24 Xuyang Zhu , Sejoon Chang , Andrew Kuik

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

In high-stakes information domains such as healthcare, where large language models (LLMs) can produce hallucinations or misinformation, retrieval-augmented generation (RAG) has been proposed as a mitigation strategy, grounding model outputs…

Information Retrieval · Computer Science 2026-04-07 Saeedeh Javadi , Sara Mirabi , Manan Gangar , Bahadorreza Ofoghi

Large Language Models (LLMs)-based question answering (QA) systems play a critical role in modern AI, demonstrating strong performance across various tasks. However, LLM-generated responses often suffer from hallucinations, unfaithful…

Computation and Language · Computer Science 2026-01-29 Yuqing Zhao , Ziyao Liu , Yongsen Zheng , Kwok-Yan Lam

In text generation, hallucinations refer to the generation of seemingly coherent text that contradicts established knowledge. One compelling hypothesis is that hallucinations occur when a language model is given a generation task outside…

Computation and Language · Computer Science 2024-08-21 Ameya Godbole , Nicholas Monath , Seungyeon Kim , Ankit Singh Rawat , Andrew McCallum , Manzil Zaheer

A common and fundamental limitation of Generative AI (GenAI) is its propensity to hallucinate. While large language models (LLM) have taken the world by storm, without eliminating or at least reducing hallucinations, real-world GenAI…

Machine Learning · Computer Science 2024-12-03 Patrice Béchard , Orlando Marquez Ayala

This study aims to develop models that generate corpus informed clarifying questions for web search, in a way that ensures the questions align with the available information in the retrieval corpus. We demonstrate the effectiveness of…

Information Retrieval · Computer Science 2024-09-30 Antonios Minas Krasakis , Andrew Yates , Evangelos Kanoulas

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

Computation and Language · Computer Science 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin

Systematic reviews are essential for evidence-based medicine, but reviewing 1.5 million+ annual publications manually is infeasible. Current AI approaches suffer from hallucinations in systematic review tasks, with studies reporting rates…

Artificial Intelligence · Computer Science 2026-01-07 Duc Ngo , Arya Rahgoza

Hallucination in generative AI is often treated as a technical failure to produce factually correct output. Yet this framing underrepresents the broader significance of hallucinated content in language models, which may appear fluent,…

Computers and Society · Computer Science 2025-10-27 Zihao Li , Weiwei Yi , Jiahong Chen

Generative artificial intelligence (AI) has brought revolutionary innovations in various fields, including medicine. However, it also exhibits limitations. In response, retrieval-augmented generation (RAG) provides a potential solution,…

Artificial Intelligence · Computer Science 2024-06-19 Rui Yang , Yilin Ning , Emilia Keppo , Mingxuan Liu , Chuan Hong , Danielle S Bitterman , Jasmine Chiat Ling Ong , Daniel Shu Wei Ting , Nan Liu

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Generative AI tools often answer questions using source documents, e.g., through retrieval augmented generation. Current groundedness and hallucination evaluations largely frame the relationship between an answer and its sources as binary…

Human-Computer Interaction · Computer Science 2026-04-10 Advait Sarkar , Christian Poelitz , Viktor Kewenig

New systems employ Machine Learning to sift through large knowledge sources, creating flexible Large Language Models. These models discern context and predict sequential information in various communication forms. Generative AI, leveraging…

Artificial Intelligence · Computer Science 2023-07-19 Ted Selker

Medical question answering requires extensive access to specialized conceptual knowledge. The current paradigm, Retrieval-Augmented Generation (RAG), acquires expertise medical knowledge through large-scale corpus retrieval and uses this…

Computation and Language · Computer Science 2025-02-20 Sichu Liang , Linhai Zhang , Hongyu Zhu , Wenwen Wang , Yulan He , Deyu Zhou

This paper presents a comprehensive analysis of how AI-generated medical responses are perceived and evaluated by non-experts. A total of 300 participants gave evaluations for medical responses that were either written by a medical doctor…

Human-Computer Interaction · Computer Science 2024-08-29 Shruthi Shekar , Pat Pataranutaporn , Chethan Sarabu , Guillermo A. Cecchi , Pattie Maes

Large Language Models have been increasingly employed in the creation of Virtual Assistants due to their ability to generate human-like text and handle complex inquiries. While these models hold great promise, challenges such as…

Computation and Language · Computer Science 2026-04-30 Dumitru Verşebeniuc , Martijn Elands , Sara Falahatkar , Chiara Magrone , Mohammad Falah , Martijn Boussé , Aki Härmä

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani
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