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Recent advances in generative modeling have led to promising results in robot motion planning, particularly through diffusion and flow matching (FM)-based models that capture complex, multimodal trajectory distributions. However, these…

Robotics · Computer Science 2025-11-13 Xiaobing Dai , Zewen Yang , Dian Yu , Fangzhou Liu , Hamid Sadeghian , Sami Haddadin , Sandra Hirche

Protein inverse folding, the design of an amino acid sequence based on a target protein structure, is a fundamental problem of computational protein engineering. Existing methods either generate sequences without leveraging external…

Quantitative Methods · Quantitative Biology 2026-03-10 Jin Han , Tianfan Fu , Wu-Jun Li

We present Piecewise Rectified Flow (PeRFlow), a flow-based method for accelerating diffusion models. PeRFlow divides the sampling process of generative flows into several time windows and straightens the trajectories in each interval via…

Machine Learning · Computer Science 2024-09-04 Hanshu Yan , Xingchao Liu , Jiachun Pan , Jun Hao Liew , Qiang Liu , Jiashi Feng

Deep generative models and neural operators have demonstrated significant potential for 3D aerodynamic inference. However, they often face inherent challenges in maintaining physical consistency and preserving high-frequency features,…

Numerical Analysis · Mathematics 2026-04-28 Ruiling Jiang , Yong Zhang , Houbiao Li

Among these, D-peptides are resistant to proteolysis, exhibit greater in vivo stability, and are easier to synthesize. Despite advances in deep learning for peptide discovery, the scarcity of natural D-protein data limits the transfer of…

Computational Engineering, Finance, and Science · Computer Science 2026-05-04 Fang Wu , Shuting Jin , Xiangru Tang , Junlin Xu , Mark Gerstein , James Zou

The de novo design of proteins refers to creating proteins with specific structures and functions that do not naturally exist. In recent years, the accumulation of high-quality protein structure and sequence data and technological…

Biomolecules · Quantitative Biology 2025-04-24 Yujie Qin , Ming He , Changyong Yu , Ming Ni , Xian Liu , Xiaochen Bo

We present ReFlow, a unified framework for monocular dynamic scene reconstruction that learns 3D motion in a novel self-correction manner from raw video. Existing methods often suffer from incomplete scene initialization for dynamic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Yanzhe Liang , Ruijie Zhu , Hanzhi Chang , Zhuoyuan Li , Jiahao Lu , Tianzhu Zhang

Diffusion-based visuomotor policies excel at modeling action distributions but are inference-inefficient, since recursively denoising from noise to policy requires many steps and heavy UNet backbones, which hinders deployment on…

Robotics · Computer Science 2026-02-16 Zhihao Chen , Yiyuan Ge , Ziyang Wang

Diffusion models create data from noise by inverting the forward paths of data towards noise and have emerged as a powerful generative modeling technique for high-dimensional, perceptual data such as images and videos. Rectified flow is a…

Channel estimation is a fundamental challenge in massive multiple-input multiple-output systems, where estimation accuracy governs the spectral efficiency and link reliability. In this work, we introduce Recursive Flow (RC-Flow), a novel…

Information Theory · Computer Science 2026-01-26 Zehua Jiang , Fenghao Zhu , Chongwen Huang , Richeng Jin , Zhaohui Yang , Xiaoming Chen , Zhaoyang Zhang , Mérouane Debbah

Mean flow (MeanFlow) enables efficient, high-fidelity image generation, yet its single-function evaluation (1-NFE) generation often cannot yield compelling results. We address this issue by introducing RMFlow, an efficient multimodal…

Machine Learning · Computer Science 2026-02-03 Yuhao Huang , Shih-Hsin Wang , Andrea L. Bertozzi , Bao Wang

Unitary Synthesis, the decomposition of a unitary matrix into a sequence of quantum gates, is a fundamental challenge in quantum compilation. Prevailing reinforcement learning (RL) approaches are often hampered by sparse reward signals,…

Quantum Physics · Physics 2026-03-05 Inhoe Koo , Hyunho Cha , Jungwoo Lee

Large-scale diffusion models have achieved remarkable performance in generative tasks. Beyond their initial training applications, these models have proven their ability to function as versatile plug-and-play priors. For instance, 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-02-21 Xiaofeng Yang , Cheng Chen , Xulei Yang , Fayao Liu , Guosheng Lin

Although diffusion models in text-to-speech have become a popular choice due to their strong generative ability, the intrinsic complexity of sampling from diffusion models harms their efficiency. Alternatively, we propose VoiceFlow, an…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-04 Yiwei Guo , Chenpeng Du , Ziyang Ma , Xie Chen , Kai Yu

Simulation-free training frameworks have been at the forefront of the generative modelling revolution in continuous spaces, leading to large-scale diffusion and flow matching models. However, such modern generative models suffer from…

Machine Learning · Computer Science 2025-10-31 Danyal Rehman , Oscar Davis , Jiarui Lu , Jian Tang , Michael Bronstein , Yoshua Bengio , Alexander Tong , Avishek Joey Bose

Proteins are macromolecules that perform essential functions in all living organisms. Designing novel proteins with specific structures and desired functions has been a long-standing challenge in the field of bioengineering. Existing…

Biomolecules · Quantitative Biology 2023-03-03 Chence Shi , Chuanrui Wang , Jiarui Lu , Bozitao Zhong , Jian Tang

Protein structure prediction is a critical and longstanding challenge in biology, garnering widespread interest due to its significance in understanding biological processes. A particular area of focus is the prediction of missing loops in…

Object pose estimation is a fundamental problem in computer vision and plays a critical role in virtual reality and embodied intelligence, where agents must understand and interact with objects in 3D space. Recently, score based generative…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Diya He , Qingchen Liu , Cong Zhang , Jiahu Qin

The flow matching has rapidly become a dominant paradigm in classical generative modeling, offering an efficient way to interpolate between two complex distributions. We extend this idea to the quantum realm and introduce the Quantum Flow…

Quantum Physics · Physics 2026-02-03 Zidong Cui , Pan Zhang , Ying Tang

The diffusion models including Denoising Diffusion Probabilistic Models (DDPM) and score-based generative models have demonstrated excellent performance in speech synthesis tasks. However, its effectiveness comes at the cost of numerous…

Sound · Computer Science 2024-02-01 Wenhao Guan , Qi Su , Haodong Zhou , Shiyu Miao , Xingjia Xie , Lin Li , Qingyang Hong
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