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Retrieval-Augmented Generation (RAG) systems using large language models (LLMs) often generate inaccurate responses due to the retrieval of irrelevant or loosely related information. Existing methods, which operate at the document level,…

Computation and Language · Computer Science 2025-04-24 Ishneet Sukhvinder Singh , Ritvik Aggarwal , Ibrahim Allahverdiyev , Muhammad Taha , Aslihan Akalin , Kevin Zhu , Sean O'Brien

Retrieval-Augmented Generation (RAG) offers a promising solution to address various limitations of Large Language Models (LLMs), such as hallucination and difficulties in keeping up with real-time updates. This approach is particularly…

Computation and Language · Computer Science 2024-06-18 Shuting Wang , Jiongnan Liu , Shiren Song , Jiehan Cheng , Yuqi Fu , Peidong Guo , Kun Fang , Yutao Zhu , Zhicheng Dou

Retrieval-Augmented Generation (RAG) addresses large language model (LLM) hallucinations by grounding responses in external knowledge, but its effectiveness is compromised by poor-quality retrieved contexts containing irrelevant or noisy…

Computation and Language · Computer Science 2025-10-27 Jiale Deng , Yanyan Shen , Ziyuan Pei , Youmin Chen , Linpeng Huang

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user queries. These systems, however, remain…

Computation and Language · Computer Science 2025-05-26 Huichi Zhou , Kin-Hei Lee , Zhonghao Zhan , Yue Chen , Zhenhao Li , Zhaoyang Wang , Hamed Haddadi , Emine Yilmaz

Recent advances in large language models (LLMs) have shown great potential to accelerate drug discovery. However, the specialized nature of biochemical data often necessitates costly domain-specific fine-tuning, posing major challenges.…

Machine Learning · Computer Science 2025-11-17 Namkyeong Lee , Edward De Brouwer , Ehsan Hajiramezanali , Tommaso Biancalani , Chanyoung Park , Gabriele Scalia

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Retrieval-augmented generation (RAG) systems combine large language models (LLMs) with external knowledge retrieval, making them highly effective for knowledge-intensive tasks. A crucial but often under-explored component of these systems…

Computation and Language · Computer Science 2025-05-19 Jiashuo Sun , Xianrui Zhong , Sizhe Zhou , Jiawei Han

Retrieval-augmented generation (RAG) improves the response quality of large language models (LLMs) by retrieving knowledge from external databases. Typical RAG approaches split the text database into chunks, organizing them in a flat…

Computation and Language · Computer Science 2025-11-18 Boyu Chen , Zirui Guo , Zidan Yang , Yuluo Chen , Junze Chen , Zhenghao Liu , Chuan Shi , Cheng Yang

Despite the impressive capabilities of large language models (LLMs) across diverse applications, they still suffer from trustworthiness issues, such as hallucinations and misalignments. Retrieval-augmented language models (RAG) have been…

Artificial Intelligence · Computer Science 2024-07-31 Mintong Kang , Nezihe Merve Gürel , Ning Yu , Dawn Song , Bo Li

Retrieval-augmented generation (RAG) frameworks enable large language models (LLMs) to retrieve relevant information from a knowledge base and incorporate it into the context for generating responses. This mitigates hallucinations and…

Computation and Language · Computer Science 2024-04-09 Pouria Rouzrokh , Shahriar Faghani , Cooper U. Gamble , Moein Shariatnia , Bradley J. Erickson

Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large Language Models (LLMs) are capable of natural language understanding and generation. But they face challenges such as hallucination and outdated knowledge. Fine-tuning is one possible solution, but it is resource-intensive and must be…

Computation and Language · Computer Science 2025-07-01 Shadman Sobhan , Mohammad Ariful Haque

Retrieval-augmented generation (RAG) is a promising method for addressing some of the memory-related challenges associated with Large Language Models (LLMs). Two separate systems form the RAG pipeline, the retriever and the reader, and the…

Computation and Language · Computer Science 2024-11-13 Alexandria Leto , Cecilia Aguerrebere , Ishwar Bhati , Ted Willke , Mariano Tepper , Vy Ai Vo

Recent advancements in large language models (LLMs) and multi-modal LLMs have been remarkable. However, these models still rely solely on their parametric knowledge, which limits their ability to generate up-to-date information and…

Artificial Intelligence · Computer Science 2025-04-22 Zihan Ling , Zhiyao Guo , Yixuan Huang , Yi An , Shuai Xiao , Jinsong Lan , Xiaoyong Zhu , Bo Zheng

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…

Computation and Language · Computer Science 2025-10-21 Yingpeng Ning , Yuanyuan Sun , Ling Luo , Yanhua Wang , Yuchen Pan , Hongfei Lin

Retrieval-Augmented Generation (RAG) is a promising approach to mitigate hallucinations in Large Language Models (LLMs) for legal applications, but its reliability is critically dependent on the accuracy of the retrieval step. This is…

Computation and Language · Computer Science 2025-10-09 Markus Reuter , Tobias Lingenberg , Rūta Liepiņa , Francesca Lagioia , Marco Lippi , Giovanni Sartor , Andrea Passerini , Burcu Sayin

Retrieval-Augmented Generation (RAG) grounds Large Language Models (LLMs) in external knowledge but often suffers from flat context representations and stateless retrieval, leading to unstable performance. We propose Stateful…

Computation and Language · Computer Science 2026-04-17 Qi Dong , Ziheng Lin , Ning Ding

Retrieval-Augmented Generation (RAG) integrates non-parametric knowledge into Large Language Models (LLMs), typically from unstructured texts and structured graphs. While recent progress has advanced text-based RAG to multi-turn reasoning…

Computation and Language · Computer Science 2025-12-11 Yucan Guo , Miao Su , Saiping Guan , Zihao Sun , Xiaolong Jin , Jiafeng Guo , Xueqi Cheng

In our study, we evaluated large language model (LLM) performance on pharmacy licensure-style question-answering tasks and developed an external knowledge integration method to improve accuracy. We benchmarked ten LLMs with varying…

The data and compute requirements of current language modeling technology pose challenges for the processing and analysis of low-resource languages. Declarative linguistic knowledge has the potential to partially bridge this data scarcity…

Computation and Language · Computer Science 2024-10-02 Bhargav Shandilya , Alexis Palmer