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Deploying Large Language Models (LLMs) in medical applications requires fact-checking capabilities to ensure patient safety and regulatory compliance. We introduce MedFact, a challenging Chinese medical fact-checking benchmark with 2,116…

Computation and Language · Computer Science 2025-11-18 Jiayi He , Yangmin Huang , Qianyun Du , Xiangying Zhou , Zhiyang He , Jiaxue Hu , Xiaodong Tao , Lixian Lai

Large language models (LLMs) exhibit extensive medical knowledge but are prone to hallucinations and inaccurate citations, which pose a challenge to their clinical adoption and regulatory compliance. Current methods, such as Retrieval…

In recent years, large language models (LLMs) have demonstrated significant success in performing varied natural language tasks such as language translation, question-answering, summarizing, fact-checking, etc. Despite LLMs' impressive…

Computation and Language · Computer Science 2025-03-03 Bishwamittra Ghosh , Sarah Hasan , Naheed Anjum Arafat , Arijit Khan

Large language models (LLMs) have shown impressive prowess in solving a wide range of tasks with world knowledge. However, it remains unclear how well LLMs are able to perceive their factual knowledge boundaries, particularly under…

Computation and Language · Computer Science 2024-11-20 Ruiyang Ren , Yuhao Wang , Yingqi Qu , Wayne Xin Zhao , Jing Liu , Hao Tian , Hua Wu , Ji-Rong Wen , Haifeng Wang

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

Large language models (LLMs) have demonstrated powerful text generation capabilities, bringing unprecedented innovation to the healthcare field. While LLMs hold immense promise for applications in healthcare, applying them to real clinical…

Computation and Language · Computer Science 2023-10-16 Rui Yang , Edison Marrese-Taylor , Yuhe Ke , Lechao Cheng , Qingyu Chen , Irene Li

Large language models (LLMs) have recently driven striking performance improvements across a range of natural language processing tasks. The factual knowledge acquired during pretraining and instruction tuning can be useful in various…

Computation and Language · Computer Science 2023-10-10 Xuming Hu , Junzhe Chen , Xiaochuan Li , Yufei Guo , Lijie Wen , Philip S. Yu , Zhijiang Guo

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Recent work has showcased the powerful capability of large language models (LLMs) in recalling knowledge and reasoning. However, the reliability of LLMs in combining these two capabilities into reasoning through multi-hop facts has not been…

Computation and Language · Computer Science 2024-06-04 Tianjie Ju , Yijin Chen , Xinwei Yuan , Zhuosheng Zhang , Wei Du , Yubin Zheng , Gongshen Liu

Large language models (LLMs) are widely used, but they often generate subtle factual errors, especially in long-form text. These errors are fatal in some specialized domains such as medicine. Existing fact-checking with grounding documents…

Computation and Language · Computer Science 2025-05-29 Yingjian Chen , Haoran Liu , Yinhong Liu , Jinxiang Xie , Rui Yang , Han Yuan , Yanran Fu , Peng Yuan Zhou , Qingyu Chen , James Caverlee , Irene Li

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

Previous studies have relied on existing question-answering benchmarks to evaluate the knowledge stored in large language models (LLMs). However, this approach has limitations regarding factual knowledge coverage, as it mostly focuses on…

Computation and Language · Computer Science 2023-10-31 Linhao Luo , Thuy-Trang Vu , Dinh Phung , Gholamreza Haffari

Answering complex real-world questions in the medical domain often requires accurate retrieval from medical Textual Knowledge Graphs (medical TKGs), as the relational path information from TKGs could enhance the inference ability of Large…

Computation and Language · Computer Science 2026-04-14 Jiatan Huang , Mingchen Li , Zonghai Yao , Dawei Li , Yuxin Zhang , Zhichao Yang , Yongkang Xiao , Feiyun Ouyang , Xiaohan Li , Shuo Han , Hong Yu

Large language models (LLMs) have demonstrated remarkable capabilities across various domains, although their susceptibility to hallucination poses significant challenges for their deployment in critical areas such as healthcare. To address…

Computation and Language · Computer Science 2024-05-13 Mengjia Niu , Hao Li , Jie Shi , Hamed Haddadi , Fan Mo

Hallucinations in large language models (LLMs) during summarization of patient-clinician dialogues pose significant risks to patient care and clinical decision-making. However, the phenomenon remains understudied in the clinical domain,…

The recent proliferation of large language models (LLMs) holds the potential to revolutionize healthcare, with strong capabilities in diverse medical tasks. Yet, deploying LLMs in high-stakes healthcare settings requires rigorous…

Machine Learning · Computer Science 2025-12-22 Shasha Zhou , Mingyu Huang , Jack Cole , Charles Britton , Ming Yin , Jan Wolber , Ke Li

Recent advancements in Large Language Models (LLMs) have showcased their proficiency in answering natural language queries. However, their effectiveness is hindered by limited domain-specific knowledge, raising concerns about the…

As language models (LMs) become integral to fields like healthcare, law, and journalism, their ability to differentiate between fact, belief, and knowledge is essential for reliable decision-making. Failure to grasp these distinctions can…

Computation and Language · Computer Science 2024-10-29 Mirac Suzgun , Tayfun Gur , Federico Bianchi , Daniel E. Ho , Thomas Icard , Dan Jurafsky , James Zou