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Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

Compressed sensing MRI is a classic inverse problem in the field of computational imaging, accelerating the MR imaging by measuring less k-space data. The deep neural network models provide the stronger representation ability and faster…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Zhiwen Fan , Liyan Sun , Xinghao Ding , Yue Huang , Congbo Cai , John Paisley

Deep learning has substantially advanced medical image segmentation, yet achieving robust generalization across diverse imaging modalities and anatomical structures remains a major challenge. A key contributor to this limitation lies in how…

Image and Video Processing · Electrical Eng. & Systems 2026-01-23 Shams Nafisa Ali , Taufiq Hasan

This work examines the use of a fully convolutional net (FCN) to find an image segment, given a pixel within this segment region. The net receives an image, a point in the image and a region of interest (RoI ) mask. The net output is a…

Computer Vision and Pattern Recognition · Computer Science 2019-02-26 Sagi Eppel

The research community has witnessed the powerful potential of self-supervised Masked Image Modeling (MIM), which enables the models capable of learning visual representation from unlabeled data. In this paper, to incorporate both the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Wenxuan Wang , Jing Wang , Chen Chen , Jianbo Jiao , Yuanxiu Cai , Shanshan Song , Jiangyun Li

Segmentation of images holds an important position in the area of image processing. It becomes more important whi le typically dealing with medical images where presurgery and post surgery decisions are required for the purpose of…

Computer Vision and Pattern Recognition · Computer Science 2010-05-25 Mrigank Rajya , Sonal Rewri , Swati Sheoran

Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Junhyeok Lee , Han Jang , Heeseong Eum , Joon Jang , Kyu Sung Choi

Nuclei instance segmentation is critical in computational pathology for cancer diagnosis and prognosis. Recently, the Segment Anything Model has demonstrated exceptional performance in various segmentation tasks, leveraging its rich priors…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Jingze Su , Tianle Zhu , Jiaxin Cai , Zhiyi Wang , Qi Li , Xiao Zhang , Tong Tong , Shu Wang , Wenxi Liu

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

Optics · Physics 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Skin lesion segmentation is one of the crucial steps for an efficient non-invasive computer-aided early diagnosis of melanoma. This paper investigates how color information, besides saliency, can be used to determine the pigmented lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Giuliana Ramella

Despite their superior performance, deep-learning methods often suffer from the disadvantage of needing large-scale well-annotated training data. In response, recent literature has seen a proliferation of efforts aimed at reducing the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Ji Yu

Medical image segmentation is crucial for computer-aided diagnosis, yet privacy constraints hinder data sharing across institutions. Federated learning addresses this limitation, but existing approaches often rely on lightweight…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tong Wang , Xingyue Zhao , Linghao Zhuang , Haoyu Zhao , Jiayi Yin , Yuyang He , Gang Yu , Bo Lin

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

Hyperspectral imaging (HSI) enables detailed land cover classification, yet low spatial resolution and sparse annotations pose significant challenges. We present a label-efficient framework that leverages spatial features from a frozen…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Yuzhen Hu , Biplab Banerjee , Saurabh Prasad

Subcellular RNA localization is a critical mechanism for the spatial control of gene expression. Its mechanism and precise functional role is not yet very well understood. Single Molecule Fluorescence in Situ Hybridization (smFISH) images…

Quantitative Methods · Quantitative Biology 2023-02-23 Arthur Imbert , Florian Mueller , Thomas Walter

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

Although deep learning greatly improves the performance of semantic segmentation, its success mainly lies in object central areas without accurate edges. As superpixels are a popular and effective auxiliary to preserve object edges, in this…

Computer Vision and Pattern Recognition · Computer Science 2020-11-25 Zhiwei Xu , Thalaiyasingam Ajanthan , Richard Hartley

Fluorescence microscopy is an essential tool for the analysis of 3D subcellular structures in tissue. An important step in the characterization of tissue involves nuclei segmentation. In this paper, a two-stage method for segmentation of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-10 David Joon Ho , Shuo Han , Chichen Fu , Paul Salama , Kenneth W. Dunn , Edward J. Delp

This paper presents an efficient automatic color image segmentation method using a seeded region growing and merging method based on square elemental regions. Our segmentation method consists of the three steps: generating seed regions,…

Computer Vision and Pattern Recognition · Computer Science 2017-11-28 Hisashi Shimodaira
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