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Related papers: LIDDIA: Language-based Intelligent Drug Discovery …

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Over the years, research in system identification has provided a rich set of methods for learning dynamical models, together with well-established theoretical guarantees. In practice, however, the choice of model class, training algorithm,…

Artificial Intelligence · Computer Science 2026-05-12 Dario Piga , Marco Forgione

In this paper, we describe and benchmark a competitor-discovery component used within an agentic AI system for fast drug asset due diligence. A competitor-discovery AI agent, given an indication, retrieves all drugs comprising the…

The discovery of novel Ionic Liquids (ILs) is hindered by critical challenges in property prediction, including limited data, poor model accuracy, and fragmented workflows. Leveraging the power of Large Language Models (LLMs), we introduce…

Artificial Intelligence · Computer Science 2025-11-17 Yuqi Yin , Yibo Fu , Siyuan Wang , Peng Sun , Hongyu Wang , Xiaohui Wang , Lei Zheng , Zhiyong Li , Zhirong Liu , Jianji Wang , Zhaoxi Sun

Agentic systems for drug discovery have demonstrated autonomous synthesis planning, literature mining, and molecular design. We ask how well they generalize. Evaluating six frameworks against 15 task classes drawn from peptide therapeutics,…

Quantitative Methods · Quantitative Biology 2026-02-12 Edward Wijaya

Scientific experimentation, a cornerstone of human progress, demands rigor in reliability, methodical control, and interpretability to yield meaningful results. Despite the growing capabilities of large language models (LLMs) in automating…

The exponential growth of academic publications poses challenges for the research process, such as literature review and procedural planning. Large Language Models (LLMs) have emerged as powerful AI tools, especially when combined with…

Applied Physics · Physics 2025-02-13 Joaquin Ramirez-Medina , Mohammadmehdi Ataei , Alidad Amirfazli

Clinical trials constitute a critical yet exceptionally challenging and costly stage of drug development (\$2.6B per drug), where protocols are encoded as complex natural language documents, motivating the use of AI systems beyond manual…

Artificial Intelligence · Computer Science 2026-04-06 Sixue Xing , Kerui Wu , Xuanye Xia , Meng Jiang , Jintai Chen , Tianfan Fu

This paper introduces LUCID-MA (Learning and Understanding Crime through Dialogue of Multiple Agents), an innovative AI powered framework where multiple AI agents collaboratively analyze and understand crime data. Our system that consists…

Multiagent Systems · Computer Science 2025-07-22 Syeda Kisaa Fatima , Tehreem Zubair , Noman Ahmed , Asifullah Khan

Artificial intelligence is reshaping scientific exploration, but most methods automate procedural tasks without engaging in scientific reasoning, limiting autonomy in discovery. We introduce Materials Agents for Simulation and Theory in…

Drug discovery is a time-consuming and expensive process, with traditional high-throughput and docking-based virtual screening hampered by low success rates and limited scalability. Recent advances in generative modelling, including…

Artificial Intelligence · Computer Science 2026-03-12 Junkai Ji , Zhangfan Yang , Dong Xu , Ruibin Bai , Jianqiang Li , Tingjun Hou , Zexuan Zhu

Today digital revolution is having a dramatic impact on the pharmaceutical industry and the entire healthcare system. The implementation of machine learning, extreme-scale computer simulations, and big data analytics in the drug design and…

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Artificial intelligence (AI) has sparked immense interest in drug discovery, but most current approaches only digitize existing high-throughput experiments. They remain constrained by conventional pipelines. As a result, they do not address…

Computers and Society · Computer Science 2025-07-29 You Wu , Philip E. Bourne , Lei Xie

Recent advancements in Large Language Models (LLMs) and related technologies such as Retrieval-Augmented Generation (RAG) and Diagram of Thought (DoT) have enabled the creation of autonomous intelligent systems capable of performing cluster…

Artificial Intelligence · Computer Science 2024-11-11 Honghao Shi , Longkai Cheng , Wenli Wu , Yuhang Wang , Xuan Liu , Shaokai Nie , Weixv Wang , Xuebin Min , Chunlei Men , Yonghua Lin

In computational biophysics, where molecular data is expanding rapidly and system complexity is increasing exponentially, large language models (LLMs) and agent-based systems are fundamentally reshaping the field. This perspective article…

Large language models ($\textbf{LLMs}$) have emerged as a powerful method for discovery. Instead of utilizing numerical data, LLMs utilize associated variable $\textit{semantic metadata}$ to predict variable relationships. Simultaneously,…

Machine Learning · Computer Science 2025-04-15 Alex Havrilla , David Alvarez-Melis , Nicolo Fusi

Keeping pace with the rapid growth of academia literature presents a significant challenge for researchers, funding bodies, and academic societies. To address the time-consuming manual effort required for scholarly discovery, we present a…

Machine Learning · Computer Science 2025-09-15 Om Vishesh , Harshad Khadilkar , Deepak Akkil

The rapid growth of scientific publications has made it increasingly difficult to keep literature reviews comprehensive and up-to-date. Though prior work has focused on automating retrieval and screening, the writing phase of systematic…

Computation and Language · Computer Science 2026-03-23 Gregory Hok Tjoan Go , Khang Ly , Anders Søgaard , Amin Tabatabaei , Maarten de Rijke , Xinyi Chen

Agentic systems are becoming more capable: agents define strategies, take actions, and interact with different environments. This autonomy poses serious challenges for overseeing and assessing agent behavior. Most current tools are limited,…

Computation and Language · Computer Science 2026-05-22 Asaf Yehudai , Lilach Eden , Michal Shmueli-Scheuer

Rapid advances in large language models and agentic AI are driving the emergence of the Internet of Agents (IoA), a paradigm where billions of autonomous software and embodied agents interact, coordinate, and collaborate to accomplish…

Networking and Internet Architecture · Computer Science 2026-03-13 Shaolong Guo , Yuntao Wang , Zhou Su , Yanghe Pan , Qinnan Hu , Tom H. Luan
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