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Precision medicine is a paradigm shift in healthcare relying heavily on genomics data. However, the complexity of biological interactions, the large number of genes as well as the lack of comparisons on the analysis of data, remain a…

Segmentation of a colour image composed of different kinds of texture regions can be a hard problem, namely to compute for an exact texture fields and a decision of the optimum number of segmentation areas in an image when it contains…

Artificial Intelligence · Computer Science 2007-05-23 Vitorino Ramos , Fernando Muge

Domain generalization (DG) aims to learn predictive models that can generalize to unseen domains. Most existing DG approaches focus on learning domain-invariant representations under the assumption of conditional distribution shift (i.e.,…

Machine Learning · Computer Science 2026-02-03 Jewon Yeom , Kyubyung Chae , Hyunggyu Lim , Yoonna Oh , Dongyoon Yang , Taesup Kim

Identifying low-dimensional sufficient structures in nonlinear sufficient dimension reduction (SDR) has long been a fundamental yet challenging problem. Most existing methods lack theoretical guarantees of exhaustiveness in identifying…

Machine Learning · Statistics 2025-12-23 Shuntuo Xu , Zhou Yu , Jian Huang

During the past decade, deep neural networks have led to fast-paced progress and significant achievements in computer vision problems, for both academia and industry. Yet despite their success, state-of-the-art image classification…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Aristotelis Ballas , Christos Diou

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

To understand complex biological systems, the research community has produced huge corpus of gene expression data. A large number of clustering approaches have been proposed for the analysis of gene expression data. However, extracting…

Computational Engineering, Finance, and Science · Computer Science 2010-03-28 Swathi. H

In mammalian cells, repair centers for DNA double-strand breaks (DSBs) have been identified. However, previous researches predominantly rely on methods that induce specific DSBs by cutting particular DNA sequences. The clustering and its…

Biological Physics · Physics 2024-10-07 Junyi Chen , Wenzong Ma , Yuqi Ma , Gen Yang

Accurate detection and segmentation of brain tumors is critical for medical diagnosis. However, current supervised learning methods require extensively annotated images and the state-of-the-art generative models used in unsupervised methods…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Wenxin Wang , Zhuo-Xu Cui , Guanxun Cheng , Chentao Cao , Xi Xu , Ziwei Liu , Haifeng Wang , Yulong Qi , Dong Liang , Yanjie Zhu

Geographic Information Systems (GIS) and related technologies have generated substantial interest among statisticians with regard to scalable methodologies for analyzing large spatial datasets. A variety of scalable spatial process models…

Machine Learning · Statistics 2021-09-10 Sudipto Banerjee

Single-cell RNA sequencing allows the quantification of gene expression at the individual cell level, enabling the study of cellular heterogeneity and gene expression dynamics. Dimensionality reduction is a common preprocessing step…

Computation · Statistics 2025-10-14 Cristian Castiglione , Alexandre Segers , Lieven Clement , Davide Risso

We consider the problem of best subset selection (BSS) under high-dimensional sparse linear regression model. Recently, Guo et al. (2020) showed that the model selection performance of BSS depends on a certain identifiability margin, a…

Statistics Theory · Mathematics 2025-04-15 Saptarshi Roy , Ambuj Tewari , Ziwei Zhu

Subspace clustering has become widely adopted for the unsupervised analysis of hyperspectral images (HSIs). Recent model-aware deep subspace clustering methods often use a two-stage framework, involving the calculation of a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Nikos Deligiannis , Aleksandra Pižurica

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

DNA storage technology offers new possibilities for addressing massive data storage due to its high storage density, long-term preservation, low maintenance cost, and compact size. To improve the reliability of stored information, base…

Machine Learning · Computer Science 2024-09-24 Bowen Liu , Jiankun Li

A novel combination of two widely-used clustering algorithms is proposed here for the detection and reduction of high data density regions. The Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm is used for the…

Computational Physics · Physics 2023-07-19 Bart J. J. Kremers , Aaron Ho , Jonathan Citrin , Karel L. van de Plassche

Face anti-spoofing approaches based on domain generalization (DG) have drawn growing attention due to their robustness for unseen scenarios. Previous methods treat each sample from multiple domains indiscriminately during the training…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Shubao Liu , Ke-Yue Zhang , Taiping Yao , Kekai Sheng , Shouhong Ding , Ying Tai , Jilin Li , Yuan Xie , Lizhuang Ma

Dimensionality reduction (DR) methods have attracted extensive attention to provide discriminative information and reduce the computational burden of the hyperspectral image (HSI) classification. However, the DR methods face many challenges…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Ramanarayan Mohanty , S L Happy , Aurobinda Routray

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…

Quantitative Methods · Quantitative Biology 2025-05-15 Tiexin Qin , Mengxu Zhu , Chunyang Li , Terry Lyons , Hong Yan , Haoliang Li

We present a framework for discriminative sequence classification where the learner works directly in the high dimensional predictor space of all subsequences in the training set. This is possible by employing a new coordinate-descent…

Machine Learning · Computer Science 2010-08-04 Georgiana Ifrim , Carsten Wiuf