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The role of chest X-ray (CXR) imaging, due to being more cost-effective, widely available, and having a faster acquisition time compared to CT, has evolved during the COVID-19 pandemic. To improve the diagnostic performance of CXR imaging a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Xiao Qi , David J. Foran , John L. Nosher , Ilker Hacihaliloglu

Domain-specific knowledge can significantly contribute to addressing a wide variety of vision tasks. However, the generation of such knowledge entails considerable human labor and time costs. This study investigates the potential of Large…

Large-scale vision 2D vision language models, such as CLIP can be aligned with a 3D encoder to learn generalizable (open-vocabulary) 3D vision models. However, current methods require supervised pre-training for such alignment, and the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Amaya Dharmasiri , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Self-supervised contrastive learning between pairs of multiple views of the same image has been shown to successfully leverage unlabeled data to produce meaningful visual representations for both natural and medical images. However, there…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Yen Nhi Truong Vu , Richard Wang , Niranjan Balachandar , Can Liu , Andrew Y. Ng , Pranav Rajpurkar

Despite significant progress in Multi-modal Large Language Models (MLLMs), their clinical reasoning capacity for multi-modal diagnosis remains largely unexamined. Current benchmarks, mostly single-modality data, can't evaluate progressive…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Gui Wang , Zehao Zhong , YongSong Zhou , Yudong Li , Ende Wu , Wooi Ping Cheah , Rong Qu , Jianfeng Ren , Linlin Shen

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large annotated datasets are essential for training robust Computer-Aided Diagnosis (CAD) models for breast cancer detection or risk prediction. However, acquiring such datasets with fine-detailed annotation is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Chest radiograph (or Chest X-Ray, CXR) is a popular medical imaging modality that is used by radiologists across the world to diagnose heart or lung conditions. Over the last decade, Convolutional Neural Networks (CNN), have seen success in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Arsh Verma , Makarand Tapaswi

Self-supervised learning (SSL) has emerged as a powerful paradigm for Chest X-ray (CXR) analysis under limited annotations. Yet, existing SSL strategies remain suboptimal for medical imaging. Masked image modeling allocates substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Wangyu Feng , Shawn Young , Lijian Xu

Existing vision-text contrastive learning like CLIP aims to match the paired image and caption embeddings while pushing others apart, which improves representation transferability and supports zero-shot prediction. However, medical…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Zifeng Wang , Zhenbang Wu , Dinesh Agarwal , Jimeng Sun

Recent advancements in Contrastive Language-Image Pre-training (CLIP) have demonstrated notable success in self-supervised representation learning across various tasks. However, the existing CLIP-like approaches often demand extensive GPU…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Yuexi Du , Brian Chang , Nicha C. Dvornek

Large Vision Language Models (LVLMs) show promise in medical applications, but their inability to faithfully ground responses in visual evidence raises serious concerns about clinical trustworthiness. While visual attribution methods are…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Guangzhi Xiong , Qiao Jin , Sanchit Sinha , Zhiyong Lu , Aidong Zhang

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

Despite the success of Vision-Language Models (VLMs) like CLIP in aligning vision and language, their proficiency in detailed, fine-grained visual comprehension remains a key challenge. We present CLIP-IN, a novel framework that bolsters…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ziteng Wang , Siqi Yang , Limeng Qiao , Lin Ma

Medical image segmentation is crucial for clinical diagnosis, yet existing models are limited by their reliance on explicit human instructions and lack the active reasoning capabilities to understand complex clinical questions. While recent…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Yu Huang , Zelin Peng , Yichen Zhao , Piao Yang , Xiaokang Yang , Wei Shen

Medical images commonly exhibit multiple abnormalities. Predicting them requires multi-class classifiers whose training and desired reliable performance can be affected by a combination of factors, such as, dataset size, data source,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Sameer Antani

Chest X-rays (CXRs) are among the most commonly used medical image modalities. They are mostly used for screening, and an indication of disease typically results in subsequent tests. As this is mostly a screening test used to rule out chest…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Ken C. L. Wong , Mehdi Moradi , Joy Wu , Tanveer Syeda-Mahmood

Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation. We pinpoint a fundamental cognitive misalignment in medical VLMs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chunzheng Zhu , Jiaqi Zeng , Junyu Jiang , Jianxin Lin , Yijun Wang

Classification and segmentation are crucial in medical image analysis as they enable accurate diagnosis and disease monitoring. However, current methods often prioritize the mutual learning features and shared model parameters, while…

Computer Vision and Pattern Recognition · Computer Science 2023-08-03 Kai Ren , Ke Zou , Xianjie Liu , Yidi Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu