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Multimodal Large Language Model (MLLM) have demonstrated strong generalization capabilities across diverse distributions and tasks, largely due to extensive pre-training datasets. Fine-tuning MLLM has become a common practice to improve…

Computation and Language · Computer Science 2024-11-19 Wenke Huang , Jian Liang , Zekun Shi , Didi Zhu , Guancheng Wan , He Li , Bo Du , Dacheng Tao , Mang Ye

Large language models (LLMs) have large potential for molecular optimization, as they can gather external chemistry tools and enable collaborative interactions to iteratively refine molecular candidates. However, this potential remains…

Artificial Intelligence · Computer Science 2025-05-28 Hyomin Kim , Yunhui Jang , Sungsoo Ahn

Large Language Models (LLMs) have demonstrated their remarkable capabilities in numerous fields. This survey focuses on how LLMs empower users, regardless of their technical background, to use human languages to automatically generate…

Software Engineering · Computer Science 2025-04-03 Nam Huynh , Beiyu Lin

Large Language Models (LLMs) have made significant strides in natural language processing and are increasingly being integrated into recommendation systems. However, their potential in educational recommendation systems has yet to be fully…

Information Retrieval · Computer Science 2025-04-14 Boxuan Ma , Md Akib Zabed Khan , Tianyuan Yang , Agoritsa Polyzou , Shin'ichi Konomi

Large language models (LLMs) can perform a wide range of tasks by following natural language instructions, without the necessity of task-specific fine-tuning. Unfortunately, the performance of LLMs is greatly influenced by the quality of…

Computation and Language · Computer Science 2023-10-23 Zhihan Zhang , Shuohang Wang , Wenhao Yu , Yichong Xu , Dan Iter , Qingkai Zeng , Yang Liu , Chenguang Zhu , Meng Jiang

Molecular property prediction is a crucial foundation for drug discovery. In recent years, pre-trained deep learning models have been widely applied to this task. Some approaches that incorporate prior biological domain knowledge into the…

Machine Learning · Computer Science 2024-08-20 Tianyu Zhang , Yuxiang Ren , Chengbin Hou , Hairong Lv , Xuegong Zhang

Multimodal Large Language Model (MLLM) relies on the powerful LLM to perform multimodal tasks, showing amazing emergent abilities in recent studies, such as writing poems based on an image. However, it is difficult for these case studies to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Chaoyou Fu , Peixian Chen , Yunhang Shen , Yulei Qin , Mengdan Zhang , Xu Lin , Jinrui Yang , Xiawu Zheng , Ke Li , Xing Sun , Yunsheng Wu , Rongrong Ji , Caifeng Shan , Ran He

Molecular optimization is a key challenge in drug discovery and material science domain, involving the design of molecules with desired properties. Existing methods focus predominantly on single-property optimization, necessitating…

Machine Learning · Computer Science 2024-09-13 Aye Phyu Phyu Aung , Jay Chaudhary , Ji Wei Yoon , Senthilnath Jayavelu

Traditional network management algorithms have relied on prior knowledge of system models and networking scenarios. In practice, a universal optimization framework is desirable where a sole optimization module can be readily applied to…

Networking and Internet Architecture · Computer Science 2024-10-24 Hoon Lee , Mintae Kim , Seunghwan Baek , Namyoon Lee , Merouane Debbah , Inkyu Lee

Large Language Models (LLMs) are revolutionizing software engineering (SE), with special emphasis on code generation and analysis. However, their applications to broader SE practices including conceptualization, design, and other non-code…

Software Engineering · Computer Science 2025-06-16 Fabian C. Peña

Deep learning has significantly advanced molecular modeling and design, enabling efficient understanding and discovery of novel molecules. In particular, large language models (LLMs) introduce a fresh research paradigm to tackle scientific…

Machine Learning · Computer Science 2025-01-06 Pengfei Liu , Jun Tao , Zhixiang Ren

The potential of large language models (LLMs) as decision support tools is increasingly being explored in fields such as business, engineering, and medicine, which often face challenging tasks of decision-making under uncertainty. In this…

Artificial Intelligence · Computer Science 2024-10-14 Ollie Liu , Deqing Fu , Dani Yogatama , Willie Neiswanger

Within the realm of software engineering, specialized tasks on code, such as program repair, present unique challenges, necessitating fine-tuning Large language models~(LLMs) to unlock state-of-the-art performance. Fine-tuning approaches…

Software Engineering · Computer Science 2025-09-23 Boyang Yang , Haoye Tian , Jiadong Ren , Hongyu Zhang , Jacques Klein , Tegawendé F. Bissyandé , Claire Le Goues , Shunfu Jin

Large language models (LLMs) have been widely adopted due to their remarkable performance across various applications, driving the accelerated development of a large number of diverse models. However, these individual LLMs show limitations…

Computation and Language · Computer Science 2025-06-13 Kaushal Kumar Maurya , KV Aditya Srivatsa , Ekaterina Kochmar

Large language models (LLMs) are becoming increasingly better at a wide range of Natural Language Processing tasks (NLP), such as text generation and understanding. Recently, these models have extended their capabilities to coding tasks,…

Machine Learning · Computer Science 2024-10-23 Nishat Raihan , Mohammed Latif Siddiq , Joanna C. S. Santos , Marcos Zampieri

The efficacy of large language models (LLMs) is heavily dependent on the quality of the underlying data, particularly within specialized domains. A common challenge when fine-tuning LLMs for domain-specific applications is the potential…

Computation and Language · Computer Science 2024-03-15 Jianwei Sun , Chaoyang Mei , Linlin Wei , Kaiyu Zheng , Na Liu , Ming Cui , Tianyi Li

Large Language Models (LLMs) aligned with human feedback have recently garnered significant attention. However, it remains vulnerable to jailbreak attacks, where adversaries manipulate prompts to induce harmful outputs. Exploring jailbreak…

Cryptography and Security · Computer Science 2024-12-23 Hongyi Li , Jiawei Ye , Jie Wu , Tianjie Yan , Chu Wang , Zhixin Li

Large Language Models (LLMs) have demonstrated remarkable performance across various domains, motivating researchers to investigate their potential use in recommendation systems. However, directly applying LLMs to recommendation tasks has…

Information Retrieval · Computer Science 2024-06-21 Zhuoxi Bai , Ning Wu , Fengyu Cai , Xinyi Zhu , Yun Xiong

Large Language Models (LLMs) can enhance their capabilities as AI assistants by integrating external tools, allowing them to access a wider range of information. While recent LLMs are typically fine-tuned with tool usage examples during…

Computation and Language · Computer Science 2025-02-27 Jie He , Jennifer Neville , Mengting Wan , Longqi Yang , Hui Liu , Xiaofeng Xu , Xia Song , Jeff Z. Pan , Pei Zhou

Large Language Models (LLMs) and Vision Language Models (VLMs) have recently shown promising capabilities in various scientific domain. In particular, these advances have opened new opportunities in drug discovery, where the ability to…

Artificial Intelligence · Computer Science 2026-05-13 Jueon Park , Wonjune Jang , Jiwoo Lee , Yein Park , Jaewoo Kang
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