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Large language models (LLMs) demonstrate exceptional performance across a variety of tasks, yet they are often affected by hallucinations and the timeliness of knowledge. Leveraging knowledge graphs (KGs) as external knowledge sources has…

Biomedical knowledge graphs (KGs) hold rich information on entities such as diseases, drugs, and genes. Predicting missing links in these graphs can boost many important applications, such as drug design and repurposing. Recent work has…

Recent advances in large language models (LLMs) have unlocked powerful reasoning and decision-making capabilities. However, their inherent dependence on static parametric memory fundamentally limits their adaptability, factual accuracy, and…

While large language models (LLMs) have made significant progress in processing and reasoning over knowledge graphs, current methods suffer from a high non-retrieval rate. This limitation reduces the accuracy of answering questions based on…

Large Language Models (LLMs) have shown remarkable capabilities across various tasks but remain prone to hallucinations in knowledge-intensive scenarios. Knowledge Base Question Answering (KBQA) mitigates this by grounding generation in…

Integrating structured knowledge from Knowledge Graphs (KGs) into Large Language Models (LLMs) remains a key challenge for symbolic reasoning. Existing methods mainly rely on prompt engineering or fine-tuning, which lose structural fidelity…

Large Language Models (LLMs) have shown unprecedented performance in various real-world applications. However, they are known to generate factually inaccurate outputs, a.k.a. the hallucination problem. In recent years, incorporating…

Large language models have achieved near-expert performance in structured reasoning domains like mathematics and programming, yet their ability to perform compositional multi-hop reasoning in specialized scientific fields remains limited.…

We introduced a methodology to efficiently exploit natural-language expressed biomedical knowledge for repurposing existing drugs towards diseases for which they were not initially intended. Leveraging on developments in Computational…

Large Language Models (LLMs) have achieved impressive results in various tasks but struggle with hallucination problems and lack of relevant knowledge, especially in deep complex reasoning and knowledge-intensive tasks. Knowledge Graphs…

Background Knowledge graphs (KGs), especially medical knowledge graphs, are often significantly incomplete, so it necessitating a demand for medical knowledge graph completion (MedKGC). MedKGC can find new facts based on the exited…

Large Language Models (LLMs) face challenges in knowledge-intensive reasoning tasks like classic multi-hop question and answering, which involves reasoning across multiple facts. This difficulty arises because the chain of thoughts (CoTs)…

Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

The task of multi-hop link prediction within knowledge graphs (KGs) stands as a challenge in the field of knowledge graph analysis, as it requires the model to reason through and understand all intermediate connections before making a…

Retrieval Augmented Generation (RAG) has gradually emerged as a promising paradigm for enhancing the accuracy and factual consistency of content generated by large language models (LLMs). However, existing RAG studies primarily focus on…

Large language models (LLMs) have achieved remarkable performance in natural language understanding and generation tasks. However, they often suffer from limitations such as difficulty in incorporating new knowledge, generating…

Retrieval-augmented generation (RAG) greatly enhances large language models (LLMs) performance in knowledge-intensive tasks. However, naive RAG methods struggle with multi-hop question answering due to their limited capacity to capture…

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Due to the remarkable reasoning ability, Large language models (LLMs) have demonstrated impressive performance in knowledge graph question answering (KGQA) tasks, which find answers to natural language questions over knowledge graphs (KGs).…

Large Language Models (LLMs) demonstrate strong reasoning abilities but face limitations such as hallucinations and outdated knowledge. Knowledge Graph (KG)-based Retrieval-Augmented Generation (RAG) addresses these issues by grounding LLM…