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Diabetic Retinopathy (DR), a vision-threatening complication of Dia-betes Mellitus (DM), is a major global concern, particularly in India, which has one of the highest diabetic populations. Prolonged hyperglycemia damages reti-nal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Arpan Maity , Aviroop Pal , MD. Samiul Islam , Tamal Ghosh

Glaucoma, a leading cause of irreversible blindness, necessitates early detection for accurate and timely intervention to prevent irreversible vision loss. In this study, we present a novel deep learning framework that leverages the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-05 Mona Ashtari-Majlan , David Masip

Today, more than 12 million people over the age of 40 suffer from ocular diseases. Most commonly, older patients are susceptible to age related macular degeneration, an eye disease that causes blurring of the central vision due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-03 Ananya Dua , Pham Hung Minh , Sajid Fahmid , Shikhar Gupta , Sophia Zheng , Vanessa Moyo , Yanran Elisa Xue

Age-Related Macular Degeneration (AMD) is an asymptomatic retinal disease which may result in loss of vision. There is limited access to high-quality relevant retinal images and poor understanding of the features defining sub-classes of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Yi-Chieh Liu , Hao-Hsiang Yang , Chao-Han Huck Yang , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , Yi-Chang James Tsai , Jesper Tegner

Diabetic retinopathy (DR) is a leading cause of blindness worldwide and a common complication of diabetes. As two different imaging tools for DR grading, color fundus photography (CFP) and infrared fundus photography (IFP) are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Fan Xiao , Junlin Hou , Ruiwei Zhao , Rui Feng , Haidong Zou , Lina Lu , Yi Xu , Juzhao Zhang

Unified multimodal models (UMMs) have emerged as a powerful paradigm in fundamental cross-modality research, demonstrating significant potential in both image understanding and generation. However, existing research in the face domain…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Junzhe Li , Sifan Zhou , Liya Guo , Xuerui Qiu , Linrui Xu , Delin Qu , Tingting Long , Chun Fan , Ming Li , Hehe Fan , Jun Liu , Shuicheng Yan

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

We present VisionFM, a foundation model pre-trained with 3.4 million ophthalmic images from 560,457 individuals, covering a broad range of ophthalmic diseases, modalities, imaging devices, and demography. After pre-training, VisionFM…

The rapid advance of generative AI is reshaping the strategic vision for R&D across industries. The unique challenges of pharmaceutical R&D will see applications of generative AI deliver value along the entire value chain from early…

Quantitative Methods · Quantitative Biology 2023-12-21 Guy Doron , Sam Genway , Mark Roberts , Sai Jasti

Ocular diseases, including diabetic retinopathy and glaucoma, present a significant public health challenge due to their high prevalence and potential for causing vision impairment. Early and accurate diagnosis is crucial for effective…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Anirudh Prabhakaran , YeKun Xiao , Ching-Yu Cheng , Dianbo Liu

Early detection of eye diseases like glaucoma, macular degeneration, and diabetic retinopathy is crucial for preventing vision loss. While artificial intelligence (AI) foundation models hold significant promise for addressing these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Danli Shi , Weiyi Zhang , Jiancheng Yang , Siyu Huang , Xiaolan Chen , Mayinuer Yusufu , Kai Jin , Shan Lin , Shunming Liu , Qing Zhang , Mingguang He

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

Image and Video Processing · Electrical Eng. & Systems 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

Significance: Access to diagnostic eye care could be expanded with high-throughput and easy-to-use tools. Phase mask-based imaging may improve the fundus camera by enabling computational refocusing with no moving parts. While phase…

Diabetic retinopathy (DR) is a diabetes complication that affects eyes. DR is a primary cause of blindness in working-age people and it is estimated that 3 to 4 million people with diabetes are blinded by DR every year worldwide. Early…

Computer Vision and Pattern Recognition · Computer Science 2019-11-21 Qilei Chen , Xinzi Sun , Ning Zhang , Yu Cao , Benyuan Liu

Despite advances in multimodal AI, current vision-based assistants often remain inefficient in collaborative tasks. We identify two key gulfs: a communication gulf, where users must translate rich parallel intentions into verbal commands…

Human-Computer Interaction · Computer Science 2026-03-16 Zhuyu Teng , Pei Chen , Yichen Cai , Ruoqing Lu , Zhaoqu Jiang , Jiayang Li , Weitao You , Lingyun Sun

Automatic diabetic retinopathy (DR) grading based on fundus photography has been widely explored to benefit the routine screening and early treatment. Existing researches generally focus on single-field fundus images, which have limited…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Junlin Hou , Jilan Xu , Fan Xiao , Rui-Wei Zhao , Yuejie Zhang , Haidong Zou , Lina Lu , Wenwen Xue , Rui Feng

Objectives: To evaluate the performance of an Artificial Intelligence (AI) system (Pegasus, Visulytix Ltd., UK), at the detection of Diabetic Retinopathy (DR) from images captured by a handheld portable fundus camera. Methods: A cohort of…

Image and Video Processing · Electrical Eng. & Systems 2019-08-20 T W Rogers , J Gonzalez-Bueno , R Garcia Franco , E Lopez Star , D Méndez Marín , J Vassallo , V C Lansingh , S Trikha , N Jaccard

We propose FD3, a fundus image enhancement method based on direct diffusion bridges, which can cope with a wide range of complex degradations, including haze, blur, noise, and shadow. We first propose a synthetic forward model through a…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Sehui Kim , Hyungjin Chung , Se Hie Park , Eui-Sang Chung , Kayoung Yi , Jong Chul Ye

Perspective distortion (PD) causes unprecedented changes in shape, size, orientation, angles, and other spatial relationships of visual concepts in images. Precisely estimating camera intrinsic and extrinsic parameters is a challenging task…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Prakash Chandra Chhipa , Meenakshi Subhash Chippa , Kanjar De , Rajkumar Saini , Marcus Liwicki , Mubarak Shah

Fontan palliation for univentricular congenital heart disease progresses to hemodynamic failure with complex flow patterns poorly characterized by conventional 2D imaging. Current assessment relies on fluoroscopic angiography, providing…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Prahlad G Menon
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