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Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Human-Computer Interaction · Computer Science 2025-10-03 Mattea Reid , Zuhairah Zainal , Khaing Zin Than , Danielle Chan , Jonathan Chan

Blind face restoration (BFR) is a fundamental and challenging problem in computer vision. To faithfully restore high-quality (HQ) photos from poor-quality ones, recent research endeavors predominantly rely on facial image priors from the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Guoqiang Liang , Qingnan Fan , Bingtao Fu , Jinwei Chen , Hong Gu , Lin Wang

This study evaluated generative methods to potentially mitigate AI bias when diagnosing diabetic retinopathy (DR) resulting from training data imbalance, or domain generalization which occurs when deep learning systems (DLS) face concepts…

Artificial Intelligence · Computer Science 2020-12-03 Philippe Burlina , Neil Joshi , William Paul , Katia D. Pacheco , Neil M. Bressler

Purpose: To investigate the changes in retinal vascular structures associated various stages of myopia by designing automated software based on an artif intelligencemodel. Methods: The study involved 1324 pediatric participants from the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Yinzheng Zhao , Zhihao Zhao , Junjie Yang , Li Li , M. Ali Nasseri , Daniel Zapp

Diabetic macular ischemia (DMI), marked by the loss of retinal capillaries in the macular area, contributes to vision impairment in patients with diabetes. Although color fundus photographs (CFPs), combined with artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Qinghua He , Hongyang Jiang , Danqi Fang , Dawei Yang , Truong X. Nguyen , Anran Ran , Clement C. Tham , Simon K. H. Szeto , Sobha Sivaprasad , Carol Y. Cheung

Glaucoma is an irreversible ocular disease and is the second leading cause of visual disability worldwide. Slow vision loss and the asymptomatic nature of the disease make its diagnosis challenging. Early detection is crucial for preventing…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Gyanendar Manohar , Ruairi O'Reilly

The global population is aging rapidly, and aging is a major risk factor for various diseases. It is an important task to predict how each individual's brain will age, as the brain supports many human functions. This capability can greatly…

Neurons and Cognition · Quantitative Biology 2025-12-05 Yifan Li , Javad Sohankar , Ji Luo , Jing Li , Yi Su

The ultra-widefield (UWF) fundus image is an attractive 3D biomarker in AI-aided myopia screening because it provides much richer myopia-related information. Though axial length (AL) has been acknowledged to be highly related to the two key…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Chong Zhong , Yang Li , Danjuan Yang , Meiyan Li , Xingyao Zhou , Bo Fu , Catherine C. Liu , A. H. Welsh

Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

This paper introduces an innovative software system for fundus image analysis that deliberately diverges from the conventional screening approach, opting not to predict specific diagnoses. Instead, our methodology mimics the diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-27 Dmitry Ryabtsev , Boris Vasilyev , Sergey Shershakov

Glaucoma is one of the leading causes of irreversible but preventable blindness in working age populations. Color fundus photography (CFP) is the most cost-effective imaging modality to screen for retinal disorders. However, its application…

Fundus fluorescein angiography (FFA) is crucial for diagnosing and monitoring retinal vascular issues but is limited by its invasive nature and restricted accessibility compared to color fundus (CF) imaging. Existing methods that convert CF…

Computer Vision and Pattern Recognition · Computer Science 2024-10-21 Weiyi Zhang , Jiancheng Yang , Ruoyu Chen , Siyu Huang , Pusheng Xu , Xiaolan Chen , Shanfu Lu , Hongyu Cao , Mingguang He , Danli Shi

Refractive error, one of the leading cause of visual impairment, can be corrected by simple interventions like prescribing eyeglasses. We trained a deep learning algorithm to predict refractive error from the fundus photographs from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Avinash V. Varadarajan , Ryan Poplin , Katy Blumer , Christof Angermueller , Joe Ledsam , Reena Chopra , Pearse A. Keane , Greg S. Corrado , Lily Peng , Dale R. Webster

Glaucoma is a top cause of irreversible blindness globally, making early detection and longitudinal follow-up pivotal to preventing permanent vision loss. Current screening and progression assessment, however, rely on single tests or…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wenbin Wei , Suyuan Yao , Cheng Huang , Xiangyu Gao

Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Ziyi Shen , Huazhu Fu , Jianbing Shen , Ling Shao

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

Fundus photography (FP) remains the primary imaging modality in screening various retinal diseases including age-related macular degeneration, diabetic retinopathy and glaucoma. FP allows the clinician to examine the ocular fundus…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Shanmukh Reddy Manne , Jose-Alain Sahel , Jay Chhablani , Kiran Kumar Vupparaboinab , Soumya Jana

The long-standing goal of multimodal AI is to build unified models in which visual understanding and visual generation mutually enhance one another. Despite recent works such as BAGEL, BLIP3o achieves remarkable progress; In practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yujun Tong , Dongliang Chang , Zijin Yin , Xintong Liu , Yuanchen Fang , Zhanyu Ma

Glaucoma causes irreversible vision loss due to damage to the optic nerve, and there is no cure for glaucoma.OCT imaging modality is an essential technique for assessing glaucomatous damage since it aids in quantifying fundus structures. To…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Huihui Fang , Fei Li , Huazhu Fu , Junde Wu , Xiulan Zhang , Yanwu Xu