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Four-dimensional (4D) Flow MRI can noninvasively measure cerebrovascular hemodynamics but remains underused clinically because current workflows rely on manual vessel segmentation and yield velocity fields sensitive to noise, artifacts, and…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Abhishek Singh , Vitaliy L. Rayz , Pavlos P. Vlachos

A method is presented for the registration of MRA and 4D Flow images, with the goal of calculating blood flow properties using both modalities simultaneously. In particular, the method produces an alignment of segmentations of vessel…

Quantitative Methods · Quantitative Biology 2025-04-28 Dan Lior , Craig G. Rusin , Justin Weigand , Kristina V. Montez , Yimo Wang , Silvana Molossi , Daniel J. Penny , Charles Puelz

In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…

Numerical Analysis · Mathematics 2024-09-25 Suncica Canic , Shihan Guo , Yifan Wang , Xiaohe Yue , Haibiao Zheng

Cerebrovascular pathology significantly contributes to cognitive decline and neurological disorders, underscoring the need for advanced tools to assess vascular integrity. Three-dimensional Time-of-Flight Magnetic Resonance Angiography (3D…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Abrar Faiyaz , Nhat Hoang , Giovanni Schifitto , Md Nasir Uddin

Analyzing the morphological attributes of blood vessels plays a critical role in the computer-aided diagnosis of many cardiovascular and ophthalmologic diseases. Although being extensively studied, segmentation of blood vessels,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yicheng Wu , Chengwei Pan , Shuqi Wang , Ming Zhang , Yong Xia , Yizhou Yu

Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Yo-Chuan Chen , Yi-Chen Lin , Ching-Ping Wang , Chia-Yen Lee , Wen-Jeng Lee , Tzung-Dau Wang , Chung-Ming Chen

Accurate patient diagnoses based on human tissue biopsies are hindered by current clinical practice, where pathologists assess only a limited number of thin 2D tissue slices sectioned from 3D volumetric tissue. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Gan Gao , Andrew H. Song , Fiona Wang , David Brenes , Rui Wang , Sarah S. L. Chow , Kevin W. Bishop , Lawrence D. True , Faisal Mahmood , Jonathan T. C. Liu

Coronary Artery Disease (CAD) diagnostic to be a major global cause of death, necessitating innovative solutions. Addressing the critical importance of early CAD detection and its impact on the mortality rate, we propose the potential of…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Atitaya Phoemsuk , Vahid Abolghasemi

A common problem which is faced by the researchers when dealing with arterial carotid imaging data is the registration of the geometrical structures between different imaging modalities or different timesteps. The use of the "Patient…

Advanced atherosclerosis in the coronary arteries is one of the leading causes of deaths worldwide while being preventable and treatable. In order to image atherosclerotic lesions (plaque), intravascular optical coherence tomography (IVOCT)…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Nils Gessert , Markus Heyder , Sarah Latus , Matthias Lutz , Alexander Schlaefer

In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…

Medical Physics · Physics 2021-04-07 Pepe Eulzer , Monique Meuschke , Carsten Klingner , Kai Lawonn

Providing closed and well-connected boundaries of coronary artery is essential to assist cardiologists in the diagnosis of coronary artery disease (CAD). Recently, several deep learning-based methods have been proposed for boundary…

There is a need to develop Monte Carlo simulations of stroke to run in-silico trials to replace animal models, explore clinical scenarios to develop hypotheses for clinical studies and for interpreting clinical monitoring. We perform…

An accurate planar visualization (curved planar reformation - CPR) of intracranial arteries is mandatory for an improved luminal and mural assessment especially in low resolution Magnetic Resonance Imaging (MRI) data sets acquired in…

Deep learning approaches have achieved state-of-the-art performance in cardiac magnetic resonance (CMR) image segmentation. However, most approaches have focused on learning image intensity features for segmentation, whereas the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Jinming Duan , Ghalib Bello , Jo Schlemper , Wenjia Bai , Timothy J W Dawes , Carlo Biffi , Antonio de Marvao , Georgia Doumou , Declan P O'Regan , Daniel Rueckert

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Accurate hepatic vessel segmentation on ultrasound (US) images can be an important tool in the planning and execution of surgery, however proves to be a challenging task due to noise and speckle. Our method comprises a reduced filter 3D…

Automated patient positioning can improve radiology workflow efficiency by reducing the time required for manual table adjustments and scout-based scan planning. We propose a learning-based framework that predicts 3D organ locations and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Kai Geissler , Daniel Mensing , Julien Senegas , Jochen G. Hirsch , Stefan Heldman , Mattias P. Heinrich

An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Mousumi Roy , Fusheng Wang , George Teodoro , Miriam B Vos , Alton Brad Farris , Jun Kong

We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Aashis Khanal , Saeid Motevali , Rolando Estrada