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Artificial Intelligence techniques can be used to classify a patient's physical activities and predict vital signs for remote patient monitoring. Regression analysis based on non-linear models like deep learning models has limited…

Artificial Intelligence · Computer Science 2024-10-28 Thanveer Shaik , Xiaohui Tao , Haoran Xie , Lin Li , Juan D. Velasquez , Niall Higgins

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance for diagnosing, monitoring and developing disease modifying…

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

Machine Learning · Computer Science 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

Analyzing vibration data using deep neural network algorithms is an effective way to detect damages in rotating machinery at an early stage. However, the black-box approach of these methods often does not provide a satisfactory solution…

Signal Processing · Electrical Eng. & Systems 2022-07-25 Oliver Mey , Deniz Neufeld

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

The current body of research on Parkinson's disease (PD) screening, monitoring, and management has evolved along two largely independent trajectories. The first research community focuses on multimodal sensing of PD-related biomarkers using…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Hassan Hizeh , Rim Chighri , Muhammad Mahboob Ur Rahman , Mohamed A. Bahloul , Ali Muqaibel , Tareq Y. Al-Naffouri

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…

Machine Learning · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson

We present a computational model that highlights the role of basal ganglia (BG) in generating simple reaching movements. The model is cast within the reinforcement learning (RL) framework with the correspondence between RL components and…

Neurons and Cognition · Quantitative Biology 2011-01-26 K. N. Magdoom , D. Subramanian , V. S. Chakravarthy , B. Ravindran , Shun-ichi Amari , N. Meenakshisundaram

Parkinson's disease (PD), a prevalent neurodegenerative disorder, significantly affects patients' daily functioning and social interactions. To facilitate a more efficient and accessible diagnostic approach for PD, we propose a dynamic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Xiaochen Huang , Xiaochen Bi , Cuihua Lv , Xin Wang , Haoyan Zhang , Wenjing Jiang , Xin Ma , Yibin Li

Parkinson's disease (PD), the second most prevalent neurodegenerative disorder worldwide, frequently presents with early-stage speech impairments. Recent advancements in Artificial Intelligence (AI), particularly deep learning (DL), have…

Sound · Computer Science 2024-09-25 Lisanne van Gelderen , Cristian Tejedor-García

This paper proposes an eXplainable Artificial Intelligence (XAI)-driven methodology to enhance the understanding of cough sound analysis for respiratory disease management. We employ occlusion maps to highlight relevant spectral regions in…

Parkinson's disease (PD) and Alzheimer's disease (AD) are the two most prevalent and incurable neurodegenerative diseases (NDs) worldwide, for which early diagnosis is critical to delay their progression. However, the high dimensionality of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Chengjia Liang , Zhenjiong Wang , Chao Chen , Ruizhi Zhang , Songxi Liang , Hai Xie , Haijun Lei , Zhongwei Huang

In this paper, an interpretable classifier using an interval type-2 fuzzy neural network for detecting patients suffering from Parkinson's Disease (PD) based on analyzing the gait cycle is presented. The proposed method utilizes clinical…

Machine Learning · Computer Science 2022-11-30 Armin Salimi-Badr , Mohammad Hashemi , Hamidreza Saffari

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

Neurons and Cognition · Quantitative Biology 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Diagnosing epilepsy requires accurate seizure detection and classification, but traditional manual EEG signal analysis is resource-intensive. Meanwhile, automated algorithms often overlook EEG's geometric and semantic properties critical…

Signal Processing · Electrical Eng. & Systems 2024-05-17 Arash Hajisafi , Haowen Lin , Yao-Yi Chiang , Cyrus Shahabi

We present a probabilistic programmed deep kernel learning approach to personalized, predictive modeling of neurodegenerative diseases. Our analysis considers a spectrum of neural and symbolic machine learning approaches, which we assess…

Machine Learning · Computer Science 2021-01-13 Alexander Lavin

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

Applications · Statistics 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

In the world, about 7 to 10 million elderly people are suffering from Parkinson's Disease (PD) disease. Parkinson's disease is a common neurological degenerative disease, and its clinical characteristics are Tremors, rigidity, bradykinesia,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-07 Elcin Huseyn

Explainable Artificial Intelligence (XAI) has emerged as a critical tool for interpreting the predictions of complex deep learning models. While XAI has been increasingly applied in various domains within acoustics, its use in bioacoustics,…

Sound · Computer Science 2025-09-11 Zubair Faruqui , Mackenzie S. McIntire , Rahul Dubey , Jay McEntee