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Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

Computation and Language · Computer Science 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

Computation and Language · Computer Science 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace

With the advent of large language models (LLMs), the vast unstructured text within millions of academic papers is increasingly accessible for materials discovery, although significant challenges remain. While LLMs offer promising few- and…

Computation and Language · Computer Science 2025-09-30 Amit K Verma , Zhisong Zhang , Junwon Seo , Robin Kuo , Runbo Jiang , Emma Strubell , Anthony D Rollett

Clinicians often need to retrieve patient-specific information from electronic health records (EHRs), a task that is time-consuming and error-prone. We present a locally deployable Clinical Contextual Question Answering (CCQA) framework…

Computation and Language · Computer Science 2026-03-30 Mikko Saukkoriipi , Nicole Hernandez , Jaakko Sahlsten , Kimmo Kaski , Otso Arponen

Large language models (LLMs) have shown considerable promise in clinical natural language processing, yet few domain-specific datasets exist to rigorously evaluate their performance on radiology tasks. In this work, we introduce an…

Computation and Language · Computer Science 2025-11-18 Namu Park , Giridhar Kaushik Ramachandran , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen , Martin Gunn

Radiology reports summarize key findings and differential diagnoses derived from medical imaging examinations. The extraction of differential diagnoses is crucial for downstream tasks, including patient management and treatment planning.…

Computation and Language · Computer Science 2024-10-15 Luoyao Chen , Revant Teotia , Antonio Verdone , Aidan Cardall , Lakshay Tyagi , Yiqiu Shen , Sumit Chopra

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Results from Randomized Controlled Trials (RCTs) establish the comparative effectiveness of interventions, and are in turn critical inputs for evidence-based care. However, results from RCTs are presented in (often unstructured) natural…

Computation and Language · Computer Science 2023-07-19 Somin Wadhwa , Jay DeYoung , Benjamin Nye , Silvio Amir , Byron C. Wallace

There has been a growing effort to replace manual extraction of data from research papers with automated data extraction based on natural language processing, language models, and recently, large language models (LLMs). Although these…

Computation and Language · Computer Science 2024-02-22 Maciej P. Polak , Dane Morgan

Automated testing plays a crucial role in ensuring software security. It heavily relies on formal specifications to validate the correctness of the system behavior. However, the main approach to defining these formal specifications is…

Software Engineering · Computer Science 2025-04-03 Hui Li , Zhen Dong , Siao Wang , Hui Zhang , Liwei Shen , Xin Peng , Dongdong She

Purpose: This study aims to use a large language model (LLM) to automate the generation of summaries from the CT simulation orders and evaluate its performance. Materials and Methods: A total of 607 CT simulation orders for patients were…

Extracting sections from clinical notes is crucial for downstream analysis but is challenging due to variability in formatting and labor-intensive nature of manual sectioning. While proprietary large language models (LLMs) have shown…

Computation and Language · Computer Science 2025-01-27 Joshua Davis , Thomas Sounack , Kate Sciacca , Jessie M Brain , Brigitte N Durieux , Nicole D Agaronnik , Charlotta Lindvall

Purpose: This study aims to evaluate the effectiveness of large language models (LLMs) in automating disease annotation of CT radiology reports. We compare a rule-based algorithm (RBA), RadBERT, and three lightweight open-weight LLMs for…

Large language models (LLMs) have demonstrated remarkable success in NLP tasks. However, there is a paucity of studies that attempt to evaluate their performances on social media-based health-related natural language processing tasks, which…

Computation and Language · Computer Science 2024-03-29 Yuting Guo , Anthony Ovadje , Mohammed Ali Al-Garadi , Abeed Sarker

Recent regulatory initiatives like the European AI Act and relevant voices in the Machine Learning (ML) community stress the need to describe datasets along several key dimensions for trustworthy AI, such as the provenance processes and…

Digital Libraries · Computer Science 2024-05-27 Joan Giner-Miguelez , Abel Gómez , Jordi Cabot

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Objective: This study aims to summarize the usage of Large Language Models (LLMs) in the process of creating a scientific review. We look at the range of stages in a review that can be automated and assess the current state-of-the-art…

Digital Libraries · Computer Science 2025-05-16 Dmitry Scherbakov , Nina Hubig , Vinita Jansari , Alexander Bakumenko , Leslie A. Lenert

The exponential growth of unstructured text data presents a fundamental challenge in modern data management and information retrieval. While Large Language Models (LLMs) have shown remarkable capabilities in natural language processing,…

Artificial Intelligence · Computer Science 2025-05-06 William Brach , Kristián Košťál , Michal Ries

Pathology reports are rich in clinical and pathological details but are often presented in free-text format. The unstructured nature of these reports presents a significant challenge limiting the accessibility of their content. In this…

Computation and Language · Computer Science 2024-11-28 Ethar Alzaid , Gabriele Pergola , Harriet Evans , David Snead , Fayyaz Minhas