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Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Concept-based models aim to explain model decisions with human-understandable concepts. However, most existing approaches treat concepts as numerical attributes, without providing complementary visual explanations that could localize the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Cristiano Patrício , Luís F. Teixeira , João C. Neves

We propose a new attribution method for neural networks developed using first principles of causality (to the best of our knowledge, the first such). The neural network architecture is viewed as a Structural Causal Model, and a methodology…

Machine Learning · Computer Science 2019-07-04 Aditya Chattopadhyay , Piyushi Manupriya , Anirban Sarkar , Vineeth N Balasubramanian

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

A small subset of explainability techniques developed initially for image recognition models has recently been applied for interpretability of 3D Convolutional Neural Network models in activity recognition tasks. Much like the models…

Machine Learning · Computer Science 2020-04-02 Liam Hiley , Alun Preece , Yulia Hicks , Supriyo Chakraborty , Prudhvi Gurram , Richard Tomsett

Artificial intelligence now outperforms humans in several scientific and engineering tasks, yet its internal representations often remain opaque. In this Perspective, we argue that explainable artificial intelligence (XAI), combined with…

Artificial Intelligence · Computer Science 2026-02-17 Ricardo Vinuesa , Steven L. Brunton , Gianmarco Mengaldo

We introduce MATEX (Multi-scale Attention and Text-guided Explainability), a novel framework that advances interpretability in medical vision-language models by incorporating anatomically informed spatial reasoning. MATEX synergistically…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Muhammad Imran , Chi Lee , Yugyung Lee

In the present paper we present the potential of Explainable Artificial Intelligence methods for decision-support in medical image analysis scenarios. With three types of explainable methods applied to the same medical image data set our…

Artificial Intelligence · Computer Science 2021-05-20 Samanta Knapič , Avleen Malhi , Rohit Saluja , Kary Främling

With the increasing adoption of predictive models trained using machine learning across a wide range of high-stakes applications, e.g., health care, security, criminal justice, finance, and education, there is a growing need for effective…

Machine Learning · Computer Science 2020-08-04 Aria Khademi , Vasant Honavar

Deep neural networks for medical image diagnosis often achieve high predictive accuracy while relying on spurious or clinically irrelevant visual cues, limiting their trustworthiness in practice. Post-hoc explanation methods are widely used…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zubair Faruqui , Rahul Dubey

Despite the significant improvements that representation learning via self-supervision has led to when learning from unlabeled data, no methods exist that explain what influences the learned representation. We address this need through our…

We investigate the effect of including domain knowledge about a robotic system's causal relations when generating explanations. To this end, we compare two methods from explainable artificial intelligence, the popular KernelSHAP and the…

Robotics · Computer Science 2021-11-05 Sindre Benjamin Remman , Inga Strümke , Anastasios M. Lekkas

Stroke is one of the leading causes of disability worldwide. The efficacy of recovery is determined by a variety of factors, including patient adherence to rehabilitation programs. One way to increase patient adherence to their…

Human-Computer Interaction · Computer Science 2024-02-20 Alicia Ouskine , Adrian D. C. Chan , Fateme Rajabiyazdi

Concept-based XAI (C-XAI) approaches to explaining neural vision models are a promising field of research, since explanations that refer to concepts (i.e., semantically meaningful parts in an image) are intuitive to understand and go beyond…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jae Hee Lee , Georgii Mikriukov , Gesina Schwalbe , Stefan Wermter , Diedrich Wolter

Recent years have seen a surge of interest in learning high-level causal representations from low-level image pairs under interventions. Yet, existing efforts are largely limited to simple synthetic settings that are far away from…

Machine Learning · Computer Science 2023-04-04 Yuejiang Liu , Alexandre Alahi , Chris Russell , Max Horn , Dominik Zietlow , Bernhard Schölkopf , Francesco Locatello

Explainable Artificial Intelligence (XAI) is essential for the transparency and clinical adoption of Clinical Decision Support Systems (CDSS). However, the real-world effectiveness of existing XAI methods remains limited and is…

Machine Learning · Computer Science 2026-01-26 Alessandro Gambetti , Qiwei Han , Hong Shen , Claudia Soares

This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano

This article discusses how the language of causality can shed new light on the major challenges in machine learning for medical imaging: 1) data scarcity, which is the limited availability of high-quality annotations, and 2) data mismatch,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-23 Daniel C. Castro , Ian Walker , Ben Glocker

While deep neural network models offer unmatched classification performance, they are prone to learning spurious correlations in the data. Such dependencies on confounding information can be difficult to detect using performance metrics if…

Machine Learning · Computer Science 2023-08-09 Susu Sun , Lisa M. Koch , Christian F. Baumgartner

Many high-performance models suffer from a lack of interpretability. There has been an increasing influx of work on explainable artificial intelligence (XAI) in order to disentangle what is meant and expected by XAI. Nevertheless, there is…

Machine Learning · Computer Science 2019-10-23 Adrien Bennetot , Jean-Luc Laurent , Raja Chatila , Natalia Díaz-Rodríguez