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Discrete diffusion models, like continuous diffusion models, generate high-quality samples by gradually undoing noise applied to datapoints with a Markov process. Gradual generation in theory comes with many conceptual benefits; for…

Machine Learning · Computer Science 2025-09-30 Alan N. Amin , Nate Gruver , Andrew Gordon Wilson

Describing particle transport at the macroscopic or mesoscopic level in non-ideal environments poses fundamental theoretical challenges in domains ranging from inter and intra-cellular transport in biology to diffusion in porous media. Yet,…

Statistical Mechanics · Physics 2013-09-11 Marta Galanti , Duccio Fanelli , Francesco Piazza

The main purpose of this work is the mathematical modelling of large populations of cells under different deterministic interactions among themselves, in balance with naturally random diffusion. We focus on cell-cell adhesion mechanisms for…

Analysis of PDEs · Mathematics 2025-03-19 Carlo Giambiagi Ferrari , Francisco Guillen-Gonzalez , Mayte Perez-Llanos , Antonio Suarez

Diffusion models generate high-dimensional data such as images by learning a process that gradually removes noise from corrupted data. Recent studies have shown that the backward dynamics of diffusion models exhibit two characteristic…

Statistical Mechanics · Physics 2026-04-14 Tomoei Takahashi , Takashi Takahashi , Yoshiyuki Kabashima

In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous landscape, where aggregates and dense domains of proteins or lipids obstruct the path of diffusing molecules. In general, hindered motion gives rise to…

Soft Condensed Matter · Physics 2010-06-16 Margaret R. Horton , Felix Höfling , Joachim O. Rädler , Thomas Franosch

Subdiffusion has been proposed as an explanation of various kinetic phenomena inside living cells. In order to fascilitate large-scale computational studies of subdiffusive chemical processes, we extend a recently suggested mesoscopic model…

Analysis of PDEs · Mathematics 2018-02-19 Emilie Blanc , Stefan Engblom , Andreas Hellander , Per Lötstedt

It is known that diffusion provokes substantial changes in continuous absorbing phase transitions. Conversely, its effect on discontinuous transitions is much less understood. In order to shed light in this direction, we study the inclusion…

Statistical Mechanics · Physics 2014-09-25 Carlos E. Fiore , Gabriel T. Landi

The mean-field limit in a weakly interacting stochastic many-particle system for multiple population species in the whole space is proved. The limiting system consists of cross-diffusion equations, modeling the segregation of populations.…

Analysis of PDEs · Mathematics 2019-09-04 Li Chen , Esther S. Daus , Ansgar Jüngel

To explain the differentiation of stem cells in terms of dynamical systems theory, models of interacting cells with intracellular protein expression dynamics are analyzed and simulated. Simulations were carried out for all possible protein…

Cell Behavior · Quantitative Biology 2015-06-15 Yusuke Goto , Kunihiko Kaneko

The replication and differentiation of spots in reaction diffusion equations are studied by extending the Gray-Scott model with self-replicating spots to include many degrees of freedom needed to model systems with many chemicals. By…

Pattern Formation and Solitons · Physics 2009-11-07 Hiroaki Takagi , Kunihiko Kaneko

Intra-tumour phenotypic heterogeneity limits accuracy of clinical diagnostics and hampers the efficiency of anti-cancer therapies. Dealing with this cellular heterogeneity requires adequate understanding of its sources, which is extremely…

Epidemic spreading often occurs in spatially heterogeneous environments, yet how quenched heterogeneity reshapes its onset and critical dynamics remains poorly understood. The diffusive epidemic process, a minimal reaction-diffusion model…

Statistical Mechanics · Physics 2026-03-24 Valentin Anfray , Hong-Yan Shih

Over the past decades, nonlocal models have been widely used to describe aggregation phenomena in biology, physics, engineering, and the social sciences. These are often derived as mean-field limits of attraction-repulsion agent-based…

Cell Behavior · Quantitative Biology 2025-05-14 Carles Falcó , Ruth E. Baker , José A. Carrillo

Diffusion is the macroscopic manifestation of disordered molecular motion. Mathematically, diffusion equations are partial differential equations describing the fluid-like large-scale dynamics of parcels of molecules. Spatially…

Fluid Dynamics · Physics 2018-10-26 F. Sattin , A. Bonato , L. Salasnich

Active transport such as fluid flow is sought in molecular communication to extend coverage, improve reliability, and mitigate interference. Flow models are often over-simplified, assuming one-dimensional diffusion with constant drift.…

Emerging Technologies · Computer Science 2024-10-30 Wayan Wicke , Tobias Schwering , Arman Ahmadzadeh , Vahid Jamali , Adam Noel , Robert Schober

The diffusion coefficient of a circular shaped inclusion in a liquid membrane is investigated by taking into account the interaction between membranes and bulk solvents of arbitrary thickness. As illustrative examples, the diffusion…

Soft Condensed Matter · Physics 2015-05-28 Kazuhiko Seki , Sanoop Ramachandran , Shigeyuki Komura

This paper aims to show that the Dirac equation coupled to an arbitrary inhomogeneous flux field admits separation in manifolds formed from the direct product of bidimensional spaces. As a direct application of these results, we study a…

High Energy Physics - Theory · Physics 2023-02-02 Joás Venâncio , Azadeh Mohammadi

Stochastic models of reaction-diffusion systems are important for the study of biochemical reaction networks where species are present in low copy numbers or if reactions are highly diffusion limited. In living cells many such systems…

Numerical Analysis · Mathematics 2015-06-15 Stefan Hellander

Diffusion models offer appealing properties for language generation, such as parallel decoding and iterative refinement, but the discrete and highly structured nature of text challenges the direct application of diffusion principles. In…

Computation and Language · Computer Science 2025-12-30 Ziqi Jin , Bin Wang , Xiang Lin , Lidong Bing , Aixin Sun

Various molecules exclusively accumulate at the front or back of migrating eukaryotic cells in response to a shallow gradient of extracellular signals. Directional sensing and signal amplification highlight the essential properties in the…

Cell Behavior · Quantitative Biology 2015-06-26 Mikiya Otsuji , Shuji Ishihara , Carl Co , Kozo Kaibuchi , Atsushi Mochizuki , Shinya Kuroda