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Recent advancements in Large Language Models (LLMs) have demonstrated significant promise in clinical diagnosis. However, current models struggle to emulate the iterative, diagnostic hypothesis-driven reasoning of real clinical scenarios.…

Computation and Language · Computer Science 2026-01-06 Qipeng Wang , Rui Sheng , Yafei Li , Huamin Qu , Yushi Sun , Min Zhu

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Multi-modal large language models (MLLMs) have shown promise in advancing healthcare. However, most existing models remain confined to single-image understanding, which greatly limits their applicability in clinical workflows. In practice,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Zhen Chen , Yihang Fu , Gabriel Madera , Mauro Giuffre , Serina Applebaum , Hyunjae Kim , Hua Xu , Qingyu Chen

Vision-threatening eye diseases pose a major global health burden, with timely diagnosis limited by workforce shortages and restricted access to specialized care. While multimodal large language models (MLLMs) show promise for medical image…

Multimodal Large Language Models (MLLMs) have achieved notable performance in computer vision tasks that require reasoning across visual and textual modalities, yet their capabilities are limited to their pre-trained data, requiring…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Mirco Bonomo , Simone Bianco

Recently, Multimodal Large Language Models (MLLMs) and Vision Language Models (VLMs) have shown great promise in language-guided perceptual tasks such as recognition, segmentation, and object detection. However, their effectiveness in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Xu Cao , Yifan Shen , Bolin Lai , Wenqian Ye , Yunsheng Ma , Joerg Heintz , Jintai Chen , Meihuan Huang , Jianguo Cao , Aidong Zhang , James M. Rehg

Recent advances in large vision-language models (LVLMs) have demonstrated strong performance on general-purpose medical tasks. However, their effectiveness in specialized domains such as dentistry remains underexplored. In particular,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Jing Hao , Yuxuan Fan , Yanpeng Sun , Kaixin Guo , Lizhuo Lin , Jinrong Yang , Qi Yong H. Ai , Lun M. Wong , Hao Tang , Kuo Feng Hung

Recent Large Vision-Language Models (LVLMs) have shown promising reasoning capabilities on text-rich images from charts, tables, and documents. However, the abundant text within such images may increase the model's sensitivity to language.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Xinmiao Yu , Xiaocheng Feng , Yun Li , Minghui Liao , Ya-Qi Yu , Xiachong Feng , Weihong Zhong , Ruihan Chen , Mengkang Hu , Jihao Wu , Dandan Tu , Duyu Tang , Bing Qin

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

Multimodal large language models (MLLMs) have achieved impressive performance across various tasks such as image captioning and visual question answer(VQA); however, they often struggle to accurately interpret depth information inherent in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Hao Yang , Hongbo Zhang , Yanyan Zhao , Bing Qin

With growing interest in recent years, medical visual question answering (Med-VQA) has rapidly evolved, with multimodal large language models (MLLMs) emerging as an alternative to classical model architectures. Specifically, their ability…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Sergio Tascon-Morales , Pablo Márquez-Neila , Raphael Sznitman

We investigate a critical yet under-explored question in Large Vision-Language Models (LVLMs): Do LVLMs genuinely comprehend interleaved image-text in the document? Existing document understanding benchmarks often assess LVLMs using…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Haolong Yan , Kaijun Tan , Yeqing Shen , Xin Huang , Zheng Ge , Xiangyu Zhang , Si Li , Daxin Jiang

Chest X-ray images are commonly used for predicting acute and chronic cardiopulmonary conditions, but efforts to integrate them with structured clinical data face challenges due to incomplete electronic health records (EHR). This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Mai A. Shaaban , Adnan Khan , Mohammad Yaqub

Mammography is the primary imaging tool for breast cancer diagnosis. Despite significant strides in applying deep learning to interpret mammography images, efforts that focus predominantly on visual features often struggle with…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Xin Wei , Yaling Tao , Changde Du , Gangming Zhao , Yizhou Yu , Jinpeng Li

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Large Vision-Language Models (LVLMs) have shown impressive capabilities across a range of tasks that integrate visual and textual understanding, such as image captioning and visual question answering. These models are trained on large-scale…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Xiaomei Zhang , Hanyu Zheng , Xiangyu Zhu , Jinghuan Wei , Junhong Zou , Zhen Lei , Zhaoxiang Zhang

Lately, researchers in artificial intelligence have been really interested in how language and vision come together, giving rise to the development of multimodal models that aim to seamlessly integrate textual and visual information.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Rajat Chawla , Arkajit Datta , Tushar Verma , Adarsh Jha , Anmol Gautam , Ayush Vatsal , Sukrit Chaterjee , Mukunda NS , Ishaan Bhola

The evaluation of Long Video Understanding (LVU) performance poses an important but challenging research problem. Despite previous efforts, the existing video understanding benchmarks are severely constrained by several issues, especially…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Junjie Zhou , Yan Shu , Bo Zhao , Boya Wu , Zhengyang Liang , Shitao Xiao , Minghao Qin , Xi Yang , Yongping Xiong , Bo Zhang , Tiejun Huang , Zheng Liu

Real-world clinical practice demands multi-image comparative reasoning, yet current medical benchmarks remain limited to single-frame interpretation. We present MedFrameQA, the first benchmark explicitly designed to test multi-image medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Suhao Yu , Haojin Wang , Juncheng Wu , Luyang Luo , Jingshen Wang , Cihang Xie , Pranav Rajpurkar , Carl Yang , Yang Yang , Kang Wang , Yannan Yu , Yuyin Zhou