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Out-of-distribution (OOD) detection is a critical task for safe deployment of learning systems in the open world setting. In this work, we investigate the use of feature density estimation via normalizing flows for OOD detection and present…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Evan D. Cook , Marc-Antoine Lavoie , Steven L. Waslander

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Despite their success, Machine Learning (ML) models do not generalize effectively to data not originating from the training distribution. To reliably employ ML models in real-world healthcare systems and avoid inaccurate predictions on…

Machine Learning · Computer Science 2023-09-29 Mohammad Azizmalayeri , Ameen Abu-Hanna , Giovanni Ciná

The growing reliance on Artificial Intelligence (AI) in critical domains such as healthcare demands robust mechanisms to ensure the trustworthiness of these systems, especially when faced with unexpected or anomalous inputs. This paper…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Max Gutbrod , David Rauber , Danilo Weber Nunes , Christoph Palm

Out-of-distribution (OOD) detection is crucial for the safety and reliability of artificial intelligence algorithms, especially in the medical domain. In the context of the Medical OOD (MOOD) detection challenge 2023, we propose a pipeline…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Out-of-distribution (OOD) detection is essential for building reliable AI systems, as models that produce outputs for invalid inputs cannot be trusted. Although deep learning (DL) is often assumed to outperform traditional machine learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Jihyeon Baek , Seunghoon Lee , Gitaek Kwon , Doohyun Park

Deep Learning models perform unreliably when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection methods help to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

Unsupervised Out-of-Distribution (OOD) detection consists in identifying anomalous regions in images leveraging only models trained on images of healthy anatomy. An established approach is to tokenize images and model the distribution of…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Sergio Naval Marimont , Vasilis Siomos , Giacomo Tarroni

Since the seminal paper of Hendrycks et al. arXiv:1610.02136, Post-hoc deep Out-of-Distribution (OOD) detection has expanded rapidly. As a result, practitioners working on safety-critical applications and seeking to improve the robustness…

Machine Learning · Statistics 2024-07-11 Paul Novello , Yannick Prudent , Joseba Dalmau , Corentin Friedrich , Yann Pequignot

Deep Learning (DL) models tend to perform poorly when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection helps to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Daria Frolova , Anton Vasiliuk , Mikhail Belyaev , Boris Shirokikh

Detecting out-of-distribution (OOD) data is crucial in machine learning applications to mitigate the risk of model overconfidence, thereby enhancing the reliability and safety of deployed systems. The majority of existing OOD detection…

Artificial Intelligence · Computer Science 2024-08-22 Christos Constantinou , Georgios Ioannides , Aman Chadha , Aaron Elkins , Edwin Simpson

In medical imaging, unsupervised out-of-distribution (OOD) detection offers an attractive approach for identifying pathological cases with extremely low incidence rates. In contrast to supervised methods, OOD-based approaches function…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lemar Abdi , Francisco Caetano , Amaan Valiuddin , Christiaan Viviers , Hamdi Joudeh , Fons van der Sommen

Avoiding out-of-distribution (OOD) data is critical for training supervised machine learning models in the medical imaging domain. Furthermore, obtaining labeled medical data is difficult and expensive since it requires expert annotators…

Computer Vision and Pattern Recognition · Computer Science 2022-10-05 Suraj Kothawade , Akshit Srivastava , Venkat Iyer , Ganesh Ramakrishnan , Rishabh Iyer

Detecting and rejecting unknown out-of-distribution (OOD) samples is critical for deployed neural networks to void unreliable predictions. In real-world scenarios, however, the efficacy of existing OOD detection methods is often impeded by…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Kai Liu , Zhihang Fu , Sheng Jin , Chao Chen , Ze Chen , Rongxin Jiang , Fan Zhou , Yaowu Chen , Jieping Ye

Out-of-distribution (OOD) detection is essential for ensuring the reliability of deep learning models in medical imaging applications. This work is motivated by the observation that class activation maps (CAMs) for in-distribution (ID) data…

Computer Vision and Pattern Recognition · Computer Science 2025-05-14 Yu-Jen Chen , Xueyang Li , Yiyu Shi , Tsung-Yi Ho

Identifying Out-of-distribution (OOD) data is becoming increasingly critical as the real-world applications of deep learning methods expand. Post-hoc methods modify softmax scores fine-tuned on outlier data or leverage intermediate feature…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Saandeep Aathreya , Shaun Canavan

Out-of-distribution detection (OOD) is a pivotal task for real-world applications that trains models to identify samples that are distributionally different from the in-distribution (ID) data during testing. Recent advances in AI,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Chaohua Li , Enhao Zhang , Chuanxing Geng , Songcan Chen

Data outside the problem domain poses significant threats to the security of AI-based intelligent systems. Aiming to investigate the data domain and out-of-distribution (OOD) data in AI quality management (AIQM) study, this paper proposes…

Artificial Intelligence · Computer Science 2023-10-13 Tinghui Ouyang , Isao Echizen , Yoshiki Seo

Out-of-Distribution (OOD) detection, i.e., identifying whether an input is sampled from a novel distribution other than the training distribution, is a critical task for safely deploying machine learning systems in the open world. Recently,…

Machine Learning · Computer Science 2023-01-13 Feng Xue , Zi He , Chuanlong Xie , Falong Tan , Zhenguo Li

Out-of-distribution (OOD) detection is a crucial part of deploying machine learning models safely. It has been extensively studied with a plethora of methods developed in the literature. This problem is tackled with an OOD score…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Jingqiu Zhou , Aojun Zhou , Hongsheng Li
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