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Dynamic lateral transport of lipids, proteins, and self-assembled structures in biomembranes plays crucial roles in diverse cellular processes. In this study, we perform a coarse-grained molecular dynamics simulation on a vesicle composed…

Soft Condensed Matter · Physics 2023-11-27 Hiroaki Ito , Naofumi Shimokawa , Yuji Higuchi

Dielectric interfaces are crucial to the behavior of charged membranes, from graphene to synthetic and biological lipid bilayers. Understanding electrolyte behavior near these interfaces remains a challenge, especially in the case of rough…

Soft Condensed Matter · Physics 2024-04-03 Nicholas Pogharian , Alexandre P. dos Santos , Ali Ehlen , Monica Olvera de la Cruz

Mobile charge in an electrolytic solution can in principle be represented as the divergence of ionic polarization. After adding explicit solvent polarization a finite volume of electrolyte can then be treated as a composite non-uniform…

Soft Condensed Matter · Physics 2021-03-03 Michiel Sprik

We propose a very simple but realistic enough model which allows to include a large number of molecules in molecular dynamics MD simulations of these bilayers, but nevertheless taking into account molecular charge distributions, flexible…

Soft Condensed Matter · Physics 2009-11-13 Z. Gamba

We study a phenomenological electropermeabilization model in a periodic medium representing biological tissue. Starting from a cell-level model describing the electric potential and the degree of porosity, we perform dimension analysis to…

Analysis of PDEs · Mathematics 2026-02-03 Tobias Gebäck , Ioanna Motschan-Armen , Irina Pettersson

The effect of AC electric fields on the elasticity of supported lipid bilayers has been investigated at the microscopic level using grazing incidence synchrotron x-ray scattering. A strong decrease in the membrane tension up to 1mN/m and a…

Soft Condensed Matter · Physics 2016-06-08 Arnaud Hemmerle , Thierry Charitat , Giovanna Fragneto , Jean Daillant

An immobile charged species provides a charged medium for transport of charge carriers that is exploited in many applications, such as permselective membranes, doped semiconductors, biological ion channels, as well as porous media and…

Chemical Physics · Physics 2019-10-09 Juhyun Song , Edwin Khoo , Martin Z. Bazant

The Poisson-Nernst-Planck (PNP) diffusional model for the immittance or impedance spectroscopy response of an electrolytic cell in a finite-length situation is extended to a general framework. In this new formalism, the bulk behavior of the…

We report here new electrical laws, derived from nonlinear electro-diffusion theory, about the effect of the local geometrical structure, such as curvature, on the electrical properties of a cell. We adopt the Poisson-Nernst-Planck (PNP)…

Subcellular Processes · Quantitative Biology 2017-11-22 Jerome Cartailler , Zeev Schuss , David Holcman

The distribution of voltage in sub-micron cellular domains remains poorly understood. In neurons, the voltage results from the difference in ionic concentrations which are continuously maintained by pumps and exchangers. However, it not…

Soft Condensed Matter · Physics 2020-03-26 Alexis Tricot , Igor M. Sokolov , David Holcman

We analyze the simplest problem of electrochemical relaxation in more than one dimension - the response of an uncharged, ideally polarizable metallic sphere (or cylinder) in a symmetric, binary electrolyte to a uniform electric field. In…

Materials Science · Physics 2009-11-11 Kevin T. Chu , Martin Z. Bazant

Understanding how electric fields destabilize biological membranes is important for electroporation-based technologies and bioelectronic interfaces. However, theoretical descriptions of this phenomenon remain fragmented. Existing theories…

Soft Condensed Matter · Physics 2026-03-25 Sirui Ning , Yannick A. D. Omar , Karthik Shekhar , Kranthi K. Mandadapu

A diffuse interface (phase field) model for an electrochemical system is developed. We describe the minimal set of components needed to model an electrochemical interface and present a variational derivation of the governing equations. With…

Materials Science · Physics 2007-05-23 J. E. Guyer , W. J. Boettinger , J. A. Warren , G. B. McFadden

In this work, we develop an extended uniform potential (UP) model for a membrane nanopore by including two different charging mechanisms of the pore walls, namely by electronic charge and by chemical charge. These two charging mechanisms…

Chemical Physics · Physics 2019-12-25 L. Zhang , P. M. Biesheuvel , I. I. Ryzhkov

We discuss the electrostatic contribution to the elastic moduli of a cell or artificial membrane placed in an electrolyte and driven by a DC electric field. The field drives ion currents across the membrane, through specific channels, pumps…

Soft Condensed Matter · Physics 2015-05-13 D. Lacoste , G. I. Menon , M. Z. Bazant , J. F. Joanny

An electric double layer capacitor (EDLC) stores energy by modulating the spatial distribution of ions in the electrolytic solution that it contains. We determine the mean-field time scales for planar EDLC relaxation to equilibrium, after a…

We study a model problem on the filtration of a conducting fluid through a porous layer. A porous medium is presented as an assemblage of identical spherical cells. Each cell consists of a porous core and liquid shell. We show the…

Analysis of PDEs · Mathematics 2026-04-20 Yulia Koroleva

Electrochemical devices often consist of multicomponent electrolyte solutions. Two processes influence the overall dynamics of these devices: the formation of electrical double layers and chemical conversion due to redox reactions. However,…

Chemical Physics · Physics 2022-06-20 Nathan Jarvey , Filipe Henrique , Ankur Gupta

Fusion of lipid bilayers in membranes is important in processes from vesicle-cell interactions (as in drug delivery) to exosome-cell signaling, while transient transmembrane electric fields are known to occur spontaneously. Two contacting…

Soft Condensed Matter · Physics 2024-04-09 Yu Zhang , Di Jin , Jacob Klein

We have studied the electrostatic screening effect of NaCl solutions on the interactions between anionic lipid bilayers in the fluid lamellar phase using a Poisson-Boltzmann based mean-field approach with constant charge and constant…

Soft Condensed Matter · Physics 2016-12-28 Bing-Sui Lu , Santosh Gupta , Michal Belička , Rudolf Podgornik , Georg Pabst