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This article introduces Bio-Eng-LMM AI chatbot, a versatile platform designed to enhance user interaction for educational and research purposes. Leveraging cutting-edge open-source Large Language Models (LLMs), Bio-Eng-LMM operates as a…

Systems and Control · Electrical Eng. & Systems 2025-04-22 Ali Forootani , Danial Esmaeili Aliabadi , Daniela Thraen

In recent years, Natural Language Processing (NLP) has played a significant role in various Artificial Intelligence (AI) applications such as chatbots, text generation, and language translation. The emergence of large language models (LLMs)…

Computation and Language · Computer Science 2024-07-10 Amanda Kau , Xuzeng He , Aishwarya Nambissan , Aland Astudillo , Hui Yin , Amir Aryani

Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

Artificial Intelligence · Computer Science 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Large Language Models (LLMs) are pre-trained on large-scale corpora and excel in numerous general natural language processing (NLP) tasks, such as question answering (QA). Despite their advanced language capabilities, when it comes to…

Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang

Clinical diagnosis is time-consuming, requiring intensive interactions between patients and medical professionals. While large language models (LLMs) could ease the pre-diagnostic workload, their limited domain knowledge hinders effective…

Computation and Language · Computer Science 2026-03-03 Liwen Sun , Xiang Yu , Ming Tan , Zhuohao Chen , Anqi Cheng , Ashutosh Joshi , Chenyan Xiong

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Retrieval-Augmented Generation (RAG) was introduced to enhance the capabilities of Large Language Models (LLMs) beyond their encoded prior knowledge. This is achieved by providing LLMs with an external source of knowledge, which helps…

Computation and Language · Computer Science 2026-03-11 Hazem Amamou , Stéphane Gagnon , Alan Davoust , Anderson R. Avila

Failure mode and effects analysis (FMEA) is an essential tool for mitigating potential failures, particularly during the ramp-up phases of new products. However, its effectiveness is often limited by the reasoning capabilities of the FMEA…

Information Retrieval · Computer Science 2025-04-01 Lukas Bahr , Christoph Wehner , Judith Wewerka , José Bittencourt , Ute Schmid , Rüdiger Daub

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Large language models (LLMs) have shown impressive capabilities in natural language processing tasks, including dialogue generation. This research aims to conduct a novel comparative analysis of two prominent techniques, fine-tuning with…

Recent advancements in large language models (LLMs) have shown impressive versatility across various tasks. To eliminate their hallucinations, retrieval-augmented generation (RAG) has emerged as a powerful approach, leveraging external…

Computation and Language · Computer Science 2025-05-30 Yuzheng Cai , Zhenyue Guo , Yiwen Pei , Wanrui Bian , Weiguo Zheng

Large Language Models (LLMs) demonstrate remarkable capabilities, yet struggle with hallucination and outdated knowledge when tasked with complex knowledge reasoning, resulting in factually incorrect outputs. Previous studies have attempted…

Computation and Language · Computer Science 2025-01-07 Derong Xu , Xinhang Li , Ziheng Zhang , Zhenxi Lin , Zhihong Zhu , Zhi Zheng , Xian Wu , Xiangyu Zhao , Tong Xu , Enhong Chen

Large language models (LLMs) have gained significant attention in various fields but prone to hallucination, especially in knowledge-intensive (KI) tasks. To address this, retrieval-augmented generation (RAG) has emerged as a popular…

Computation and Language · Computer Science 2024-04-23 Xiaoxi Li , Zhicheng Dou , Yujia Zhou , Fangchao Liu

The generative capabilities of LLM models offer opportunities for accelerating tasks but raise concerns about the authenticity of the knowledge they produce. To address these concerns, we present a computational approach that evaluates the…

Artificial Intelligence · Computer Science 2025-03-25 Ahmed Abdeen Hamed , Alessandro Crimi , Magdalena M. Misiak , Byung Suk Lee

Large Language Models (LLMs) have showcased impressive reasoning abilities, but often suffer from hallucinations or outdated knowledge. Knowledge Graph (KG)-based Retrieval-Augmented Generation (RAG) remedies these shortcomings by grounding…

Information Retrieval · Computer Science 2025-05-29 Martin Böckling , Heiko Paulheim , Andreea Iana

Large Language Models (LLMs) exhibit remarkable capabilities but are prone to generating inaccurate or hallucinatory responses. This limitation stems from their reliance on vast pretraining datasets, making them susceptible to errors in…

Computation and Language · Computer Science 2024-04-02 Chi-Min Chan , Chunpu Xu , Ruibin Yuan , Hongyin Luo , Wei Xue , Yike Guo , Jie Fu