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Intelligent medical image segmentation methods are rapidly evolving and being increasingly applied, yet they face the challenge of domain transfer, where algorithm performance degrades due to different data distributions between source and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Andrew Seohwan Yu , Mohsen Hariri , Xuecen Zhang , Mingrui Yang , Vipin Chaudhary , Xiaojuan Li

A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Honghai Zhang , Karan Rao , Milan Sonka

Purpose: To organize a knee MRI segmentation challenge for characterizing the semantic and clinical efficacy of automatic segmentation methods relevant for monitoring osteoarthritis progression. Methods: A dataset partition consisting of 3D…

Manual annotation of volumetric medical images, such as magnetic resonance imaging (MRI) and computed tomography (CT), is a labor-intensive and time-consuming process. Recent advancements in foundation models for video object segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Yuwen Chen , Zafer Yildiz , Qihang Li , Yaqian Chen , Haoyu Dong , Hanxue Gu , Nicholas Konz , Maciej A. Mazurowski

Objective: We evaluate a fully-automated femoral cartilage segmentation model for measuring T2 relaxation values and longitudinal changes using multi-echo spin echo (MESE) MRI. We have open sourced this model and corresponding…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Kevin A. Thomas , Dominik Krzemiński , Łukasz Kidziński , Rohan Paul , Elka B. Rubin , Eni Halilaj , Marianne S. Black , Akshay Chaudhari , Garry E. Gold , Scott L. Delp

Menisci are cartilaginous tissue found within the knee that contribute to joint lubrication and weight dispersal. Damage to menisci can lead to onset and progression of knee osteoarthritis (OA), a condition that is a leading cause of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Oliver Mills , Philip Conaghan , Nishant Ravikumar , Samuel Relton

The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities. In this paper, we present an…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Quan Wang , Dijia Wu , Le Lu , Meizhu Liu , Kim L. Boyer , Shaohua Kevin Zhou

Analyzing knee cartilage thickness and strain under load can help to further the understanding of the effects of diseases like Osteoarthritis. A precise segmentation of the cartilage is a necessary prerequisite for this analysis. This…

The purpose of this work is to develop a deep learning-based method for knee menisci segmentation in 3D ultrashort echo time (UTE) cones magnetic resonance (MR) imaging, and to automatically determine MR relaxation times, namely the T1,…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Michal Byra , Mei Wu , Xiaodong Zhang , Hyungseok Jang , Ya-Jun Ma , Eric Y Chang , Sameer Shah , Jiang Du

The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Chaowei Tan , Zhennan Yan , Shaoting Zhang , Kang Li , Dimitris N. Metaxas

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Knee osteoarthritis is a degenerative joint disease that induces chronic pain and disability. Bone morphological analysis is a promising tool to understand the mechanical aspect of this disorder. This study proposes a 2D bone morphological…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yun Xin Teoh , Alice Othmani , Siew Li Goh , Juliana Usman , Khin Wee Lai

The recently proposed Segment Anything Model (SAM) is a general tool for image segmentation, but it requires additional adaptation and careful fine-tuning for medical image segmentation, especially for small, irregularly-shaped, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Yaxi Chen , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Accurate segmentation of the ventricles from cardiac magnetic resonance images (CMRIs) is crucial for enhancing the diagnosis and analysis of heart conditions. Deep learning-based segmentation methods have recently garnered significant…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Hong Zheng , Yucheng Chen , Nan Mu , Xiaoning Li

Precision medicine in musculoskeletal imaging requires scalable measurement infrastructure. We developed a modular system that converts routine MRI into standardized quantitative biomarkers suitable for clinical decision support. Promptable…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Gabrielle Hoyer , Michelle W Tong , Rupsa Bhattacharjee , Valentina Pedoia , Sharmila Majumdar

Functional MRI (fMRI) is commonly used for interpreting neural activities across the brain. Numerous accelerated fMRI techniques aim to provide improved spatiotemporal resolutions. Among these, simultaneous multi-slice (SMS) imaging has…

Image and Video Processing · Electrical Eng. & Systems 2021-05-11 Omer Burak Demirel , Burhaneddin Yaman , Logan Dowdle , Steen Moeller , Luca Vizioli , Essa Yacoub , John Strupp , Cheryl A. Olman , Kâmil Uğurbil , Mehmet Akçakaya

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

In the current study, our purpose is to evaluate the feasibility of applying deep learning (DL) enabled algorithms to quantify bilateral knee biomarkers in healthy controls scanned at 0.55T and compared with 3.0T. The current study assesses…

Computer Vision and Pattern Recognition · Computer Science 2023-10-27 Rupsa Bhattacharjee , Zehra Akkaya , Johanna Luitjens , Pan Su , Yang Yang , Valentina Pedoia , Sharmila Majumdar

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Ipek Oguz , Honghai Zhang , Milan Sonka

In medical image analysis, automated segmentation of multi-component anatomical structures, which often have a spectrum of potential anomalies and pathologies, is a challenging task. In this work, we develop a multi-step approach using…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Boyeong Woo , Craig Engstrom , William Baresic , Jurgen Fripp , Stuart Crozier , Shekhar S. Chandra
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