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Phylogenetic inference can potentially result in a more accurate tree using data from multiple loci. However, if the loci are incongruent--due to events such as incomplete lineage sorting or horizontal gene transfer--it can be misleading to…

Populations and Evolution · Quantitative Biology 2016-03-10 Kevin Gori , Tomasz Suchan , Nadir Alvarez , Nick Goldman , Christophe Dessimoz

Fitting distances to tree metrics and ultrametrics are two widely used methods in hierarchical clustering, primarily explored within the context of numerical taxonomy. Given a positive distance function…

Data Structures and Algorithms · Computer Science 2025-04-25 Amir Carmel , Debarati Das , Evangelos Kipouridis , Evangelos Pipis

We herein introduce a new method of interpretable clustering that uses unsupervised binary trees. It is a three-stage procedure, the first stage of which entails a series of recursive binary splits to reduce the heterogeneity of the data…

Methodology · Statistics 2011-10-28 Ricardo Fraiman , Badih Ghattas , Marcela Svarc

Metabarcoding on amplicons is rapidly expanding as a method to produce molecular based inventories of microbial communities. Here, we work on freshwater diatoms, which are microalgae possibly inventoried both on a morphological and a…

Quantitative Methods · Quantitative Biology 2016-11-30 J. -M. Frigerio , F. Rimet , A. Bouchez , E. Chancerel , P. Chaumeil , F. Salin , S. Thérond , M. Kahlert , A. Franc

Metaproteomics has become a crucial omics technology for studying microbiomes. In this area, the Unipept ecosystem, accessible at https://unipept.ugent.be, has emerged as an invaluable resource for analyzing metaproteomic data. It offers…

Molecular Networks · Quantitative Biology 2023-11-14 Tim Van Den Bossche , Pieter Verschaffelt , Tibo Vande Moortele , Peter Dawyndt , Lennart Martens , Bart Mesuere

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Monte Carlo Tree Search (MCTS) algorithms have achieved great success on many challenging benchmarks (e.g., Computer Go). However, they generally require a large number of rollouts, making their applications costly. Furthermore, it is also…

Machine Learning · Computer Science 2020-02-27 Anji Liu , Jianshu Chen , Mingze Yu , Yu Zhai , Xuewen Zhou , Ji Liu

Utility mining has emerged as an important and interesting topic owing to its wide application and considerable popularity. However, conventional utility mining methods have a bias toward items that have longer on-shelf time as they have a…

Databases · Computer Science 2020-11-30 Chunkai Zhang , Zilin Du , Yuting Yang , Wensheng Gan , Philip S. Yu

Combinatorial optimization problems for clustering are known to be NP-hard. Most optimization methods are not able to find the global optimum solution for all datasets. To solve this problem, we propose a global optimal path-based…

Machine Learning · Computer Science 2019-09-18 Qidong Liu , Ruisheng Zhang

We propose a new clustering approach, called optimality-based clustering, that clusters data points based on their latent decision-making preferences. We assume that each data point is a decision generated by a decision-maker who…

Optimization and Control · Mathematics 2022-02-15 Zahed Shahmoradi , Taewoo Lee

The primary goal in cluster analysis is to discover natural groupings of objects. The field of cluster analysis is crowded with diverse methods that make special assumptions about data and address different scientific aims. Despite its…

Genomics · Quantitative Biology 2018-06-07 Gary K. Chen , Eric Chi , John Ranola , Kenneth Lange

1) Biological collections house millions of specimens with digital images increasingly available through open-access platforms. However, most imaging protocols were developed for human interpretation without considering automated analysis…

High-dimensional omics datasets are routinely visualized as heatmaps, where color intensities reveal co-expression patterns and correlations. However, modern omics technologies increasingly generate matrices so large that existing visual…

Genomics · Quantitative Biology 2026-04-21 Osho Rawal , Rex Lu , Edgar Gonzalez-Kozlova , Sacha Gnjatic , Zeynep H. Gümüş

Precision and reliability of barcode-based biodiversity assessment can be affected at several steps during acquisition and analysis of the data. Identification of barcodes is one of the crucial steps in the process and can be accomplished…

Populations and Evolution · Quantitative Biology 2017-04-19 Oleksandr Holovachov , Quiterie Haenel , Sarah J. Bourlat , Ulf Jondelius

Designing search algorithms for finding global optima is one of the most active research fields, recently. These algorithms consist of two main categories, i.e., classic mathematical and metaheuristic algorithms. This article proposes a…

Neural and Evolutionary Computing · Computer Science 2018-09-26 Benyamin Ghojogh , Saeed Sharifian , Hoda Mohammadzade

The analysis of data streams has received considerable attention over the past few decades due to sensors, social media, etc. It aims to recognize patterns in an unordered, infinite, and evolving stream of observations. Clustering this type…

Machine Learning · Computer Science 2022-01-14 Mohammed Oualid Attaoui , Hanene Azzag , Mustapha Lebbah , Nabil Keskes

Monte Carlo tree search (MCTS) is one of the most capable online search algorithms for sequential planning tasks, with significant applications in areas such as resource allocation and transit planning. Despite its strong performance in…

Artificial Intelligence · Computer Science 2024-10-31 Ziyan An , Hendrik Baier , Abhishek Dubey , Ayan Mukhopadhyay , Meiyi Ma

Recent studies revealed an important interplay between the detailed structure of fibration symmetric circuits and the functionality of biological and non-biological networks within which they have be identified. The presence of these…

Molecular Networks · Quantitative Biology 2022-04-06 Higor S. Monteiro , Ian Leifer , Saulo D. S. Reis , José S. Andrade, , Hernan A. Makse

Recent results have shown that the MCTS algorithm (a new, adaptive, randomized optimization algorithm) is effective in a remarkably diverse set of applications in Artificial Intelligence, Operations Research, and High Energy Physics. MCTS…

Artificial Intelligence · Computer Science 2015-09-29 S. Ali Mirsoleimani , Aske Plaat , Jaap van den Herik

OPTICS is a density-based clustering algorithm that performs well in a wide variety of applications. For a set of input objects, the algorithm creates a so-called reachability plot that can be either used to produce cluster membership…

Quantitative Methods · Quantitative Biology 2013-09-10 Gabor Ivan , Vince Grolmusz