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This study introduces a novel approach for early Type 2 Diabetes Mellitus (T2DM) risk prediction using a tabular transformer (TabTrans) architecture to analyze longitudinal patient data. By processing patients` longitudinal health records…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Sulaiman Khan , Md. Rafiul Biswas , Zubair Shah

Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…

Machine Learning · Computer Science 2024-06-10 Azmine Toushik Wasi

Objective: Numerous glucose prediction algorithm have been proposed to empower type 1 diabetes (T1D) management. Most of these algorithms only account for input such as glucose, insulin and carbohydrate, which limits their performance.…

Tissues and Organs · Quantitative Biology 2024-12-20 Chengyuan Liu , Josep Vehi , Nick Oliver , Pantelis Georgiou , Pau Herrero

Type 1 Diabetes (T1D) is an autoimmune disease leading to insulin insufficiency. Thus, patients require lifelong insulin therapy, which has a side effect of hypoglycemia. Hypoglycemia is a critical state of decreased blood glucose levels…

Machine Learning · Computer Science 2026-01-21 Beyza Cinar , Louisa van den Boom , Maria Maleshkova

Accurately predicting blood glucose (BG) levels of ICU patients is critical, as both hypoglycemia (BG < 70 mg/dL) and hyperglycemia (BG > 180 mg/dL) are associated with increased morbidity and mortality. This study presents a…

Machine Learning · Computer Science 2025-06-24 Hadi Mehdizavareh , Arijit Khan , Simon Lebech Cichosz

Regular monitoring of glycemic status is essential for diabetes management, yet conventional blood-based testing can be burdensome for frequent assessment. The sclera contains superficial microvasculature that may exhibit diabetes related…

Image and Video Processing · Electrical Eng. & Systems 2026-03-16 Muhammad Ahmed Khan , Manqiang Peng , Ding Lin , Saif Ur Rehman Khan

People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Sustained high levels of blood glucose in type 2 diabetes (T2DM) can have disastrous long-term health consequences. An essential component of clinical interventions for T2DM is monitoring dietary intake to keep plasma glucose levels within…

Quantitative Methods · Quantitative Biology 2022-06-24 Zepeng Huo , Bobak J. Mortazavi , Theodora Chaspari , Nicolaas Deutz , Laura Ruebush , Ricardo Gutierrez-Osuna

We develop a new model of insulin-glucose dynamics for forecasting blood glucose in type 1 diabetics. We augment an existing biomedical model by introducing time-varying dynamics driven by a machine learning sequence model. Our model…

Machine Learning · Statistics 2020-08-10 Andrew C. Miller , Nicholas J. Foti , Emily Fox

In this paper, we build a new, simple, and interpretable mathematical model to estimate and forecast physiology related to the human glucose-insulin system, constrained by available data. By constructing a simple yet flexible model class…

Quantitative Methods · Quantitative Biology 2022-09-22 M. Sirlanci , M. E. Levine , C. C. Low Wang , D. J. Albers , A. M. Stuart

In the context of time-series forecasting, we propose a LSTM-based recurrent neural network architecture and loss function that enhance the stability of the predictions. In particular, the loss function penalizes the model, not only on the…

Signal Processing · Electrical Eng. & Systems 2020-09-09 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses…

Machine Learning · Computer Science 2019-07-30 Ramin Ramazi , Christine Perndorfer , Emily Soriano , Jean-Philippe Laurenceau , Rahmatollah Beheshti

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

Due to the sensitive nature of diabetes-related data, preventing them from being shared between studies, progress in the field of glucose prediction is hard to assess. To address this issue, we present GLYFE (GLYcemia Forecasting…

Signal Processing · Electrical Eng. & Systems 2020-06-30 Maxime De Bois , Mehdi Ammi , Mounîm A. El Yacoubi

We consider the question of 30-minute prediction of blood glucose levels measured by continuous glucose monitoring devices, using clinical data. While most studies of this nature deal with one patient at a time, we take a certain percentage…

Machine Learning · Computer Science 2017-07-20 H. N. Mhaskar , S. V. Pereverzyev , M. D. van der Walt

Every year, humanity loses about 1.5 million persons due to diabetic disease. Therefore continuous monitoring of diabetes is highly needed, but the conventional approach, i.e., fingertip pricking, causes mental and physical pain to the…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Abdelrhman Y. Soliman , Ahmed M. Nor , Octavian Fratu , Simona Halunga , Osama A. Omer , Ahmed S. Mubark

Biosensor data has the potential ability to improve disease control and detection. However, the analysis of these data under free-living conditions is not feasible with current statistical techniques. To address this challenge, we introduce…

Applications · Statistics 2021-03-30 Marcos Matabuena , Alexander Petersen , Juan C. Vidal , Francisco Gude

Type 1 diabetes (T1D) management can be significantly enhanced through the use of predictive machine learning (ML) algorithms, which can mitigate the risk of adverse events like hypoglycemia. Hypoglycemia, characterized by blood glucose…

Quantitative Methods · Quantitative Biology 2025-04-02 Beyza Cinar , Jennifer Daniel Onwuchekwa , Maria Maleshkova

Continuous Blood Glucose (CGM) monitors have revolutionized the ability of diabetics to manage their blood glucose, and paved the way for artificial pancreas systems. In this paper we augment CGM data with sensor input collected by a smart…

Human-Computer Interaction · Computer Science 2023-02-06 Sam Royston

Blood glucose prediction is an important component of biomedical technology for managing diabetes with automated insulin delivery systems. Machine learning and deep learning algorithms hold the potential to advance this technology. However,…

Software Engineering · Computer Science 2024-06-14 Miriam K. Wolff , Sam Royston , Anders Lyngvi Fougner , Hans Georg Schaathun , Martin Steinert , Rune Volden