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Infectious disease outbreaks can have a disruptive impact on public health and societal processes. As decision making in the context of epidemic mitigation is hard, reinforcement learning provides a methodology to automatically learn…

We present a data-driven optimal control framework that can be viewed as a generalization of the path integral (PI) control approach. We find iterative feedback control laws without parameterization based on probabilistic representation of…

Systems and Control · Computer Science 2016-02-02 Yunpeng Pan , Evangelos A. Theodorou , Michail Kontitsis

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

Machine Learning · Computer Science 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fairness-Aware Interpretable Modeling (FAIM), to improve model…

Machine Learning · Computer Science 2024-03-11 Mingxuan Liu , Yilin Ning , Yuhe Ke , Yuqing Shang , Bibhas Chakraborty , Marcus Eng Hock Ong , Roger Vaughan , Nan Liu

In this study, we present an integro-differential model to simulate the local spread of infections. The model incorporates a standard susceptible-infected-recovered (\textit{SIR}-) model enhanced by an integral kernel, allowing for…

Dynamical Systems · Mathematics 2023-07-20 Moritz Schäfer , Karol Niedzielewski , Thomas Götz , Tyll Krüger

The ongoing pandemic has highlighted the importance of reliable and efficient clinical trials in healthcare. Trial sites, where the trials are conducted, are chosen mainly based on feasibility in terms of medical expertise and access to a…

Machine Learning · Computer Science 2022-04-14 Rakshith S Srinivasa , Cheng Qian , Brandon Theodorou , Jeffrey Spaeder , Cao Xiao , Lucas Glass , Jimeng Sun

A decision maker typically (i) incorporates training data to learn about the relative effectiveness of treatments, and (ii) chooses an implementation mechanism that implies an ``optimal'' predicted outcome distribution according to some…

Econometrics · Economics 2025-05-29 Anders Bredahl Kock , David Preinerstorfer

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Optimization and Control · Mathematics 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

Epidemics of infectious diseases are an important threat to public health and global economies. Yet, the development of prevention strategies remains a challenging process, as epidemics are non-linear and complex processes. For this reason,…

Machine Learning · Computer Science 2020-03-31 Pieter Libin , Arno Moonens , Timothy Verstraeten , Fabian Perez-Sanjines , Niel Hens , Philippe Lemey , Ann Nowé

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…

Optimization and Control · Mathematics 2020-06-03 Ceyda Yaba Best , Amin Khademi , Burak Eksioglu

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

The outbreak of COVID-19 has highlighted the intricate interplay between public health and economic stability on a global scale. This study proposes a novel reinforcement learning framework designed to optimize health and economic outcomes…

Machine Learning · Computer Science 2024-05-01 Maeghal Jain , Ziya Uddin , Wubshet Ibrahim

Machine learning is used to make decisions for individuals in various fields, which require us to achieve good prediction accuracy while ensuring fairness with respect to sensitive features (e.g., race and gender). This problem, however,…

Machine Learning · Computer Science 2021-03-01 Yoichi Chikahara , Shinsaku Sakaue , Akinori Fujino , Hisashi Kashima

In this work we demonstrate how to automate parts of the infectious disease-control policy-making process via performing inference in existing epidemiological models. The kind of inference tasks undertaken include computing the posterior…

Infectious diseases are among the most prominent threats to mankind. When preventive health care cannot be provided, a viable means of disease control is the isolation of individuals, who may be infected. To study the impact of isolation,…

Dynamical Systems · Mathematics 2018-04-10 Stefan Ruschel , Tiago Pereira , Serhiy Yanchuk , Lai-Sang Young

The COVID-19 pandemic underscored the urgent need for fair and effective allocation of scarce resources, from hospital beds to vaccine distribution. In this paper, we study a healthcare rationing problem where identical units of a resource…

Computer Science and Game Theory · Computer Science 2025-05-19 Zhaohong Sun

Artificial intelligence supports healthcare professionals with predictive modeling, greatly transforming clinical decision-making. This study addresses the crucial need for fairness and explainability in AI applications within healthcare to…

Machine Learning · Computer Science 2024-11-27 Chia-Hsuan Chang , Xiaoyang Wang , Christopher C. Yang

Epidemics such as COVID-19 pose serious threats to public health and our society, and it is critical to investigate effective methods to control the spread of epidemics over networks. Prior works on epidemic control often assume complete…

Artificial Intelligence · Computer Science 2023-10-13 Wenxiang Dong , Zhanjiang Chen , H. Vicky Zhao