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Breast cancer has the highest incidence and second highest mortality rate for women in the US. Our study aims to utilize deep learning for benign/malignant classification of mammogram tumors using a subset of cases from the Digital Database…

Computer Vision and Pattern Recognition · Computer Science 2017-05-19 Darvin Yi , Rebecca Lynn Sawyer , David Cohn , Jared Dunnmon , Carson Lam , Xuerong Xiao , Daniel Rubin

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

Genomics · Quantitative Biology 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Rushabh Patel

Prostate cancer (PCa) is the second deadliest form of cancer in males, and it can be clinically graded by examining the structural representations of Gleason tissues. This paper proposes \RV{a new method} for segmenting the Gleason tissues…

Computer Vision and Pattern Recognition · Computer Science 2021-07-27 Taimur Hassan , Bilal Hassan , Ayman El-Baz , Naoufel Werghi

Breast cancer remains a leading cause of cancer-related mortality among women worldwide. Ultrasound imaging, widely used due to its safety and cost-effectiveness, plays a key role in early detection, especially in patients with dense breast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mohammad Abbadi , Yassine Himeur , Shadi Atalla , Wathiq Mansoor

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

Computational Engineering, Finance, and Science · Computer Science 2025-05-16 Binesh Sadanandan , Vahid Behzadan

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

Breast cancer is a prevalent form of cancer among women, with over 1.5 million women being diagnosed each year. Unfortunately, the survival rates for breast cancer patients in certain third-world countries, like South Africa, are alarmingly…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Brennon Maistry , Absalom E. Ezugwu

Lung cancer is a significant cause of mortality worldwide, emphasizing the importance of early detection for improved survival rates. In this study, we propose a machine learning (ML) tool trained on data from the PLCO Cancer Screening…

Machine Learning · Computer Science 2023-08-24 Pierre-Louis Benveniste , Julie Alberge , Lei Xing , Jean-Emmanuel Bibault

The high-dimensional feature space of the hyperspectral imagery poses major challenges to the processing and analysis of the hyperspectral data sets. In such a case, dimensionality reduction is necessary to decrease the computational…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Mustafa Ustuner

Prostate cancer (PCa) is a leading cause of cancer-related mortality in men, and accurate identification of clinically significant PCa (csPCa) is critical for timely intervention. Transrectal ultrasound (TRUS) is widely used for prostate…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Zetian Feng , Juan Fu , Xuebin Zou , Hongsheng Ye , Hong Wu , Jianhua Zhou , Yi Wang

Whole gland (WG) segmentation of the prostate plays a crucial role in detection, staging and treatment planning of prostate cancer (PCa). Despite promise shown by deep learning (DL) methods, they rely on the availability of a considerable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Alvaro Fernandez-Quilez , Steinar Valle Larsen , Morten Goodwin , Thor Ole Gulsurd , Svein Reidar Kjosavik , Ketil Oppedal

Background: Artificial intelligence (AI) is improving the efficiency and accuracy of cancer diagnostics. The performance of pathology AI systems has been almost exclusively evaluated on European and US cohorts from large centers. For global…

Magnetic Resonance Imaging (MRI) plays an important role in identifying clinically significant prostate cancer (csPCa), yet automated methods face challenges such as data imbalance, variable tumor sizes, and a lack of annotated data. This…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Alessia Hu , Regina Beets-Tan , Lishan Cai , Eduardo Pooch

The biggest Breast cancer is increasingly a major factor in female fatalities, overtaking heart disease. While genetic factors are important in the growth of breast cancer, new research indicates that environmental factors also play a…

Machine Learning · Computer Science 2023-09-27 Muhammad Shoaib Farooq , Mehreen Ilyas

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Lung cancer, the second leading cause of cancer-related deaths, is primarily linked to long-term tobacco smoking (85% of cases). Surprisingly, 10-15% of cases occur in non-smokers. In 2020, approximately 2 million people were affected…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Imama Ajmi , Abhishek Das