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We train a neural network to predict distributional responses in gene expression following genetic perturbations. This is an essential task in early-stage drug discovery, where such responses can offer insights into gene function and inform…

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Deep latent variable models learn condensed representations of data that, hopefully, reflect the inner workings of the studied phenomena. Unfortunately, these latent representations are not statistically identifiable, meaning they cannot be…

Machine Learning · Statistics 2025-06-02 Stas Syrota , Yevgen Zainchkovskyy , Johnny Xi , Benjamin Bloem-Reddy , Søren Hauberg

While deep learning has seen many recent applications to drug discovery, most have focused on predicting activity or toxicity directly from chemical structure. Phenotypic changes exhibited in cellular images are also indications of the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Philip T. Jackson , Yinhai Wang , Sinead Knight , Hongming Chen , Thierry Dorval , Martin Brown , Claus Bendtsen , Boguslaw Obara

Diffusion Generative Models (DGM) have rapidly surfaced as emerging topics in the field of computer vision, garnering significant interest across a wide array of deep learning applications. Despite their high computational demand, these…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Denisha Thakkar , Vincent Quoc-Huy Trinh , Sonal Varma , Samira Ebrahimi Kahou , Hassan Rivaz , Mahdi S. Hosseini

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

This paper presents a novel approach that leverages domain variability to learn representations that are conditionally invariant to unwanted variability or distractors. Our approach identifies both spurious and invariant latent features…

Machine Learning · Computer Science 2023-07-04 Hananeh Aliee , Ferdinand Kapl , Soroor Hediyeh-Zadeh , Fabian J. Theis

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Detecting objects seamlessly blended into their surroundings represents a complex task for both human cognitive capabilities and advanced artificial intelligence algorithms. Currently, the majority of methodologies for detecting camouflaged…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Jianwei Zhao , Xin Li , Fan Yang , Qiang Zhai , Ao Luo , Zicheng Jiao , Hong Cheng

The recent wave of large-scale text-to-image diffusion models has dramatically increased our text-based image generation abilities. These models can generate realistic images for a staggering variety of prompts and exhibit impressive…

Machine Learning · Computer Science 2023-09-14 Alexander C. Li , Mihir Prabhudesai , Shivam Duggal , Ellis Brown , Deepak Pathak

Recent advancements in diffusion models have enabled the generation of realistic deepfakes from textual prompts in natural language. While these models have numerous benefits across various sectors, they have also raised concerns about the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Roberto Amoroso , Davide Morelli , Marcella Cornia , Lorenzo Baraldi , Alberto Del Bimbo , Rita Cucchiara

Recently, diffusion transformers have gained wide attention with its excellent performance in text-to-image and text-to-vidoe models, emphasizing the need for transformers as backbone for diffusion models. Transformer-based models have…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Nithin Gopalakrishnan Nair , Jeya Maria Jose Valanarasu , Vishal M. Patel

Diffusion models (DMs) embark a new era of generative modeling and offer more opportunities for efficient generating high-quality and realistic data samples. However, their widespread use has also brought forth new challenges in model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Jingyao Xu , Yuetong Lu , Yandong Li , Siyang Lu , Dongdong Wang , Xiang Wei

We propose a method to facilitate exploration and analysis of new large data sets. In particular, we give an unsupervised deep learning approach to learning a latent representation that captures semantic similarity in the data set. The core…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Gary B Huang , Huei-Fang Yang , Shin-ya Takemura , Pat Rivlin , Stephen M Plaza

Diffusion models, such as Stable Diffusion, have shown incredible performance on text-to-image generation. Since text-to-image generation often requires models to generate visual concepts with fine-grained details and attributes specified…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Xuehai He , Weixi Feng , Tsu-Jui Fu , Varun Jampani , Arjun Akula , Pradyumna Narayana , Sugato Basu , William Yang Wang , Xin Eric Wang

A change points detection aims to catch an abrupt disorder in data distribution. Common approaches assume that there are only two fixed distributions for data: one before and another after a change point. Real-world data are richer than…

Machine Learning · Computer Science 2022-04-18 Alexander Stepikin , Evgenia Romanenkova , Alexey Zaytsev

Cell detection in microscopy images is important to study how cells move and interact with their environment. Most recent deep learning-based methods for cell detection use convolutional neural networks (CNNs). However, inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Royden Wagner , Karl Rohr

Diffusion Probabilistic Models have recently shown remarkable performance in generative image modeling, attracting significant attention in the computer vision community. However, while a substantial amount of diffusion-based research has…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Yijun Yang , Huazhu Fu , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb , Lei Zhu

Training supervised deep neural networks that perform defect detection and segmentation requires large-scale fully-annotated datasets, which can be hard or even impossible to obtain in industrial environments. Generative AI offers…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Gabriele Valvano , Antonino Agostino , Giovanni De Magistris , Antonino Graziano , Giacomo Veneri
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