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Related papers: HistoSmith: Single-Stage Histology Image-Label Gen…

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Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

We present DiffInfinite, a hierarchical diffusion model that generates arbitrarily large histological images while preserving long-range correlation structural information. Our approach first generates synthetic segmentation masks,…

Instance-level image classification tasks have traditionally relied on single-instance labels to train models, e.g., few-shot learning and transfer learning. However, set-level coarse-grained labels that capture relationships among…

Machine Learning · Computer Science 2023-11-21 Renyu Zhang , Aly A. Khan , Yuxin Chen , Robert L. Grossman

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

Multiplex imaging is revolutionizing pathology by enabling the simultaneous visualization of multiple biomarkers within tissue samples, providing molecular-level insights that traditional hematoxylin and eosin (H&E) staining cannot provide.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-06 Hyun-Jic Oh , Junsik Kim , Zhiyi Shi , Yichen Wu , Yu-An Chen , Peter K Sorger , Hanspeter Pfister , Won-Ki Jeong

The digitization of histology slides has revolutionized pathology, providing massive datasets for cancer diagnosis and research. Self-supervised and vision-language models have been shown to effectively mine large pathology datasets to…

Semi-supervised medical image segmentation aims to leverage limited annotated data and rich unlabeled data to perform accurate segmentation. However, existing semi-supervised methods are highly dependent on the quality of self-generated…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Xinyu Liu , Wuyang Li , Yixuan Yuan

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu

The segmentation of histological images is critical for various biomedical applications, yet the lack of annotated data presents a significant challenge. We propose a microscopy pseudo labeling pipeline utilizing unsupervised image…

Image and Video Processing · Electrical Eng. & Systems 2024-12-05 Arthur Boschet , Armand Collin , Nishka Katoch , Julien Cohen-Adad

Significant disparities between the features of natural images and those inherent to histopathological images make it challenging to directly apply and transfer pre-trained models from natural images to histopathology tasks. Moreover, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zhenfeng Zhuang , Min Cen , Yanfeng Li , Fangyu Zhou , Lequan Yu , Baptiste Magnier , Liansheng Wang

Semantic segmentation has made significant progress in recent years thanks to deep neural networks, but the common objective of generating a single segmentation output that accurately matches the image's content may not be suitable for…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Lukas Zbinden , Lars Doorenbos , Theodoros Pissas , Adrian Thomas Huber , Raphael Sznitman , Pablo Márquez-Neila

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng

Latent Diffusion Models (LDMs) can generate high-fidelity images from noise, offering a promising approach for augmenting histopathology images for training cancer grading models. While previous works successfully generated high-fidelity…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Man M. Ho , Elham Ghelichkhan , Yosep Chong , Yufei Zhou , Beatrice Knudsen , Tolga Tasdizen

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib