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Structural variants compose the majority of human genetic variation, but are difficult to assess using current genomic sequencing technologies. Optical mapping technologies, which measure the size of chromosomal fragments between labeled…

Quantitative Methods · Quantitative Biology 2019-10-10 Weiwei Li , Jan Hannig , Corbin Jones

We propose a class of estimators for deconvolution in mixture models based on a simple two-step "bin-and-smooth" procedure applied to histogram counts. The method is both statistically and computationally efficient: by exploiting recent…

Methodology · Statistics 2018-08-01 Oscar Hernan Madrid Padilla , Nicholas G. Polson , James G. Scott

We describe a multi-order spectrograph concept suitable for 8m-class telescopes, using the intrinsic spectral resolution of Superconducting Tunneling Junction detectors to sort the spectral orders. The spectrograph works at low orders, 1-5…

In the rapidly growing field of wearable technology, optical devices are emerging as a significant innovation, offering non-invasive methods for analyzing skin and underlying tissue properties. Despite their promise, progress has been…

Human-Computer Interaction · Computer Science 2024-07-18 Nazim A. Belabbaci , Mohammad Arif Ul Alam

Determining the spectral density of a molecular system immersed in a proteomic scaffold and in contact to a solvent is a fundamental challenge in the coarse-grained description of, e.g., electron and energy transfer dynamics. Once the…

Quantum Physics · Physics 2014-11-04 Leonardo A. Pachon , Paul Brumer

Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…

Optical photothermal microscopy is a powerful, emerging method that overcomes the diffraction limit in infrared hyperspectral imaging by utilizing a visible probe laser beam to detect local temperature-induced modulation at the visible…

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

This article describes the design and construction of a portable, compact, and cost-effective microspectrophotometer (MSP) that operates in the range of (200_800 nm). This microscope spectrophotometer records highresolution absorption and…

Optics · Physics 2025-11-07 Negar Karpourazar , Keyvan Khosh Abady , Peter M. Rentzepis

Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Sohag Kumar Mondal , Md. Simul Hasan Talukder , Mohammad Aljaidi , Rejwan Bin Sulaiman , Md Mohiuddin Sarker Tushar , Amjad A Alsuwaylimi

The knowledge of absolute fluxes of reactive species such as radicals or energetic ions to the surface is crucial for understanding the growth or etching of thin films. These species have due to their high reactivity very low densities and…

Plasma Physics · Physics 2011-05-16 Jan Benedikt , Dirk Ellerweg , Achim von Keudell

A novel THz near-field spectrometer is presented which allows to perform biological and medical studies with high spectral resolution combined with a spatial resolution down to l/100. In the setup an aperture much smaller than the used…

Biological Physics · Physics 2009-11-07 S. Mair , B. Gompf , M. Dressel

Optical flow estimation is very challenging in situations with transparent or occluded objects. In this work, we address these challenges at the task level by introducing Amodal Optical Flow, which integrates optical flow with amodal…

Computer Vision and Pattern Recognition · Computer Science 2024-05-08 Maximilian Luz , Rohit Mohan , Ahmed Rida Sekkat , Oliver Sawade , Elmar Matthes , Thomas Brox , Abhinav Valada

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated…

To design semiconductor-based optical devices, the optical properties of the used semiconductor materials must be precisely measured over a large band. Transmission spectroscopy stands out as an inexpensive and widely available method for…

For a large Hermitian matrix $A\in \mathbb{C}^{N\times N}$, it is often the case that the only affordable operation is matrix-vector multiplication. In such case, randomized method is a powerful way to estimate the spectral density (or…

Numerical Analysis · Mathematics 2015-11-24 Lin Lin

A custom, flat field, extreme ultraviolet EUV spectrometer built specifically for use with low power light sources that operate under ultrahigh vacuum conditions is reported. The spectral range of the spectrometer extends from 4 nm to 40…

We report on the development of a compact (volume $\approx$ 100\:cm$^3$), multimode diffraction-limited Raman spectrograph and probe designed to be compact as possible. The spectrograph uses `off the shelf' optics, a custom 3D-printed…

Instrumentation and Detectors · Physics 2020-03-04 Christopher H. Betters , Joss Bland-Hawthorn , Salah Sukkarieh , Itandehui Gris-Sanchez , Sergio G. Leon-Saval

Aims: We aim to extend our current observational understanding of the integrated planet Earth spectropolarimetry from the optical to the near-infrared wavelengths. Major biomarkers like O$_{\rm 2}$ and water vapor are strong flux absorbents…

Earth and Planetary Astrophysics · Physics 2015-06-18 P. A. Miles-Páez , E. Pallé , M. R. Zapatero Osorio

Deploying deep learning models on embedded systems has been challenging due to limited computing resources. The majority of existing work focuses on accelerating image classification, while other fundamental vision problems, such as object…

Computer Vision and Pattern Recognition · Computer Science 2021-01-27 Zhen Dong , Dequan Wang , Qijing Huang , Yizhao Gao , Yaohui Cai , Tian Li , Bichen Wu , Kurt Keutzer , John Wawrzynek