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High-frequency physiological waveform modality offers deep, real-time insights into patient status. Recently, physiological foundation models based on Photoplethysmography (PPG), such as PPG-GPT, have been shown to predict critical events,…

Machine Learning · Computer Science 2025-09-29 Saurabh Kataria , Davood Fattahi , Minxiao Wang , Ran Xiao , Matthew Clark , Timothy Ruchti , Mark Mai , Xiao Hu

Clinical laboratory tests provide essential biochemical measurements for diagnosis and treatment, but are limited by intermittent and invasive sampling. In contrast, photoplethysmogram (PPG) is a non-invasive, continuously recorded signal…

Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models…

Early prediction of pediatric cardiac arrest (CA) is critical for timely intervention in high-risk intensive care settings. We introduce PedCA-FT, a novel transformer-based framework that fuses tabular view of EHR with the derived textual…

Photoplethysmogram (PPG) is increasingly used to provide monitoring of the cardiovascular system under ambulatory conditions. Wearable devices like smartwatches use PPG to allow long term unobtrusive monitoring of heart rate in free living…

Machine Learning · Computer Science 2019-03-22 Shyam A , Vignesh Ravichandran , Preejith S. P , Jayaraj Joseph , Mohanasankar Sivaprakasam

To date, developing a good model for early intensive care unit (ICU) mortality prediction is still challenging. This paper presents a patient based predictive modeling framework (PPMF) to improve the performance of ICU mortality prediction…

Machine Learning · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this…

Machine Learning · Computer Science 2019-02-12 Reza Sadeghi , Tanvi Banerjee , William Romine

Much of the information of breathing is contained within the photoplethysmography (PPG) signal, through changes in venous blood flow, heart rate and stroke volume. We aim to leverage this fact, by employing a novel deep learning framework…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Harry J. Davies , Danilo P. Mandic

Prognostication for comatose post-cardiac arrest patients is a critical challenge that directly impacts clinical decision-making in the ICU. Clinical information that informs prognostication is collected serially over time. Shortly after…

Machine Learning · Computer Science 2025-08-11 Xiaobin Shen , Jonathan Elmer , George H. Chen

Despite the population of the noninvasive, economic, comfortable, and easy-to-install photoplethysmography (PPG), it is still lacking a mathematically rigorous and stable algorithm which is able to simultaneously extract from a…

Neurons and Cognition · Quantitative Biology 2017-09-05 Antonio Cicone , Hau-Tieng Wu

Photoplethysmography (PPG) sensors allow for non-invasive and comfortable heart-rate (HR) monitoring, suitable for compact wrist-worn devices. Unfortunately, Motion Artifacts (MAs) severely impact the monitoring accuracy, causing high…

A wrist-worn PPG sensor coupled with a lightweight algorithm can run on a MCU to enable non-invasive and comfortable monitoring, but ensuring robust PPG-based heart-rate monitoring in the presence of motion artifacts is still an open…

Signal Processing · Electrical Eng. & Systems 2022-03-31 Matteo Risso , Alessio Burrello , Daniele Jahier Pagliari , Simone Benatti , Enrico Macii , Luca Benini , Massimo Poncino

Photoplethysmography (PPG) is one of the most widely captured biosignals for clinical prediction tasks, yet PPG-based algorithms are typically trained on small-scale datasets of uncertain quality, which hinders meaningful algorithm…

Machine Learning · Computer Science 2026-03-24 Mohammad Moulaeifard , Philip J. Aston , Peter H. Charlton , Nils Strodthoff

Objective- Heart rate monitoring using wrist type Photoplethysmographic (PPG) signals is getting popularity because of construction simplicity and low cost of wearable devices. The task becomes very difficult due to the presence of various…

Intensive care unit (ICU) data are highly irregular, heterogeneous, and temporally fragmented, posing challenges for generalizable clinical prediction. We present PULSE-ICU, a self-supervised foundation model that learns event-level ICU…

Machine Learning · Computer Science 2025-12-01 Sejeong Jang , Joo Heung Yoon , Hyo Kyung Lee

Early and accurate diagnosis of pulmonary hypertension (PH) is essential for optimal patient management. Differentiating between pre-capillary and post-capillary PH is critical for guiding treatment decisions. This study develops and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Fubao Zhu , Yang Zhang , Gengmin Liang , Jiaofen Nan , Yanting Li , Chuang Han , Danyang Sun , Zhiguo Wang , Chen Zhao , Wenxuan Zhou , Jian He , Yi Xu , Iokfai Cheang , Xu Zhu , Yanli Zhou , Weihua Zhou

Continuous monitoring and patient acuity assessments are key aspects of Intensive Care Unit (ICU) practice, but both are limited by time constraints imposed on healthcare providers. Moreover, anticipating clinical trajectories remains…

Multi-channel photoplethysmography (PPG) sensors have found widespread adoption in wearable devices for monitoring cardiac health. Channels thereby serve different functions -- whereas green is commonly used for metrics such as heart rate…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Manuel Meier , Berken Utku Demirel , Christian Holz

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

Quantitative Methods · Quantitative Biology 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist…

Machine Learning · Computer Science 2023-10-24 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes , Jun Shen , Jiang Bian
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